Summary
Field investigations at settlements in Didessa valley and Angar valley in Wollega province, Ethiopia, suggested the presence of drug-resistant strains ofTrypanosoma congolense.
Laboratory experiments using mice confirmed a high incidence of resistance to homidium bromide, a phenanthridinium drug.
Résumé
Des investigations en brousse, dans des établissements de Didessa et d'Angar Vallée, dans la province de Wollega, en Ethiopie, ont suggéré l'existence de souches deTrypanosoma congolense résistantes aux trypanocides.
Les recherches en Laboratoire sur souris ont confirmé leur haut degré de résistance au bromure d'homidium, dérivé de la phenanthridine.
Sumario
Se sospechó la presencia de cepas resistentes deTrypanosoma congolense, a las drogas utilizadas en el campo en investigaciones llevadas a cabo en los caceríos del valle de Didessa y Angar en la provincia de Wollega, Etiopía.
Experimentos con ratones en el laboratorio confirmaron una alta incidencia de la resistencia del tripanosoma al bromuro de homidio y al fenantridinio.
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Scott, J.M., Pegram, R.G. A high incidence ofTrypanosoma congolense strains resistant to homidium bromide in Ethiopia. Trop Anim Health Prod 6, 215–221 (1974). https://doi.org/10.1007/BF02383280
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DOI: https://doi.org/10.1007/BF02383280