Summary
The effect of lidocaine on the increase of intraocular pressure induced by succinylcholine was studied in patients 6 to 85 years of age. Three groups of patients were studied. One group of eight patients received lidocaine 1 mg·kg-1 before succinylcholine and a control group of ten patients did not have lidocaine. Anaesthesia was induced with thiopentone 5 mg·kg-1 and maintained with nitrous oxide 50 per cent with oxygen and halothane 1.0-1.5 per cent. The tracheae of all patients were intubated.
Lidocaine in doses of 1.0 to 2.0 mg·kg-1 did not prevent transient rise in intraocular pressure following administration of succinylcholine and tracheal intubation.
Résumé
Ľétude porte sur trois groupes de patients et évalue ľeffet de ľinjection de lidocaíne sur ľaugmentation de la tension intraoculaire dgmentationclenchgmentatione par la succinylcholine. Un premier groupe de huit patients a reçu lidocaíne 1 mg·kg-1 avant la succinylcholine, un deuxième de dix patients, lidocaíne 2 mg·kg1 avant la succinylcholine, et un troisième de dix patients n’a reçu que la succinylcholine et a servi de contrôle. Ľanesthísie fut réalisée avec du thiopental 5 mgékg-1 suivi de protoxyde ďazote-oxygène à 50 pour cent avec halothane 1.0 à 1.5 pour cent. Tous les patients furent intubés.
La lidocaíne aux doses de 1.0 à 2.0 mg·kg-1 n’a pas empêché ľaugmentation transitoire de la tension intraoculaire provoquée par ľadministration de succinylcholine et ľintubation trachéale.
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References
Usubiaga, J.E., Wlkinski, J.A., Usubiaga, L.E. &Molina, F. Intravenous lidocaine in the prevention of postoperative muscle pain caused by succinylcholine administration. Anes. Anal.46: 225, (1967).
Sharma, H.R. Role of xylocaine in the prevention of postsuxamethonium muscle pain. Abstract F8/95 from the World Federation of Anesthesiologists. Japan, 1972.
Lincoff, H.A., Ellis, C.H., DeVoe, A.G., DeBeer, E.J., Impastanto, D.J., Berg, S., Orkin, L. &Magda, J. The effect of succinylcholine on intraocular pressure. Amer. J. Ophthal.40: 501 (1955).
Wynands, J.E. &Crowell, D.E. Intraocular tension in association with succinylcholine and endotracheal intubation: a preliminary report. Canad. Anaesth.Soc. J.7: 39(1960).
Taylor, T.H., Mulcahy, M. &Nightingale, D.A. Suxamethonium chloride in intraocular surgery. Brit. J. Anaesth.40: 113 (1968).
Pandey, K., Badola, R.P. &Kumar, S. Time course of intraocular hypertension produced by suxamethonium. Brit. J. Anaesth.44: 191 (1972).
Sobel, A.M. Hexafluorenium, succinylcholine, and intraocular tension. Anes. Anal.41: 399(1962).
Miller, R.D., Walter, L.W. &Hickey, R.F. Inhibition of succinylcholine-induced increased intraocular pressure by non-depolarizing muscle relaxants. Anesthesiology29: 123(1968).
Carballo, A.S. Succinylcholine and acetazolamide (Diamox) in anaesthesia for ocular surgery. Can. Anaes. Soc. J.12: 486(1965).
Craythorne, N.W.B., Rottenstein, H.S. &Dripps, R.D. The effect of succinylcholine on the intraocular pressure in adults, infants and children during general anesthesia. Anesthesiology21: 59 (1960).
Miller, R.D. &Walter, L.W. Inhibition of succinylcholine induced increased intragastric pressure by non-depolarizing muscle relaxants and lidocaine. Anesthesiology34: 185(1971).
Davanger, M. The difference in ocular pressure in the two eyes of the same person. Acta Ophthalmologica43: 299 (1965).
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Smith, R.B., Babinski, M. & Leano, N. The effect of lidocaine on succinylcholine-induced rise in intraocular pressure. Canad. Anaesth. Soc. J. 26, 482–483 (1979). https://doi.org/10.1007/BF03006161
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DOI: https://doi.org/10.1007/BF03006161