Abstract
The design, performance, and projected economics of a new conceptual process for thein situ solvent extraction of butanol within a multiphase fluidized bed bioreactor are discussed. The process appears to have the potential to increase the effective concentration of product over tenfold while maintaining actual concentrations in contact with the organism at 10 g/L, i.e., below the threshold of inhibition. If this performance can be realized in commercial operation, the selling price to yield a 30% pretax return on investment could be reduced from over $1.25 per pound of butanol for the present process to $0.59 per pound for the new process.
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Busche, R.M., Allen, B.R. Technoeconomics of butanol extractive fermentation in a multiphase fluidized bed bioreactor. Appl Biochem Biotechnol 20, 357–374 (1989). https://doi.org/10.1007/BF02936496
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DOI: https://doi.org/10.1007/BF02936496