Abstract
Radioactivity from orally administered radiolabeled dihomo-γ-linolenic acid (20∶3ω6) was recovered from the liver, plasma and brain lipid fractions. After administration the fatty acid was metabolized to arachidonic acid, the 22 carbon chain length fatty acid, and was also β-oxidized. However, 22 hr after administration of [1-14C]20∶3 between one-third and one-half of the recovered radioactivity was still associated with dihomo-γ-linolenic acid in the liver and plasma lipid fractions. Orally administered dihomo-γ-linolenic acid is incorporated into lipid fractions and is, therefore, available in the metabolic pool for PGE1 synthesis.
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Hassam, A.G., Crawford, M.A. The incorporation of orally administered radiolabeled dihomo γ-linolenic acid (20∶3ω6) into rat tissue lipids and its conversion to arachidonic acid. Lipids 13, 801–803 (1978). https://doi.org/10.1007/BF02533479
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DOI: https://doi.org/10.1007/BF02533479