Abstract
Catalyzed by 10−5 M ionic iron in 80% ethanol,N-acetylcysteine added to linoleic acid hydroperoxide, forming a thiobond. Reaction of a specific isomer of the hydroperoxide, 13-hydroperoxy-trans-11,cis-9-octadecadienoic acid, andN-acetylcysteine, forms a number of products, of which two were identified as addition compounds. One addition product was 9-S-(N-acetylcysteine)-13-hydroxy-10-ethoxy-trans-11-octadecenoic acid, and the other was 9-S-(N-acetylcysteine)-10,13-dihydroxy-trans-11-octadecenoic acid.
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Gardner, H.W., Weisleder, D. & Kleiman, R. Addition ofN-acetylcysteine to linoleic acid hydroperoxide. Lipids 11, 127–134 (1976). https://doi.org/10.1007/BF02532662
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DOI: https://doi.org/10.1007/BF02532662