Abstract
The purpose of the present study was to measure oxygen uptake\((\dot VO_2 )\) at the ventilatory threshold (VT) in patients with congenital heart disease using a progressive exercise protocol on a treadmill and to evaluate the validity and feasibility of this procedure. Eight control subjects and seventeen patients performed a maximal exercise test with breath-by-breath measurement of ventilation and gas exchange variables. VT(VE) was determined by the change in the ventilatory equivalent for\(\dot VO_2 \) and carbon dioxide output, VT(V-sl) by the V-slope method, and the lactate threshold (LT) by the change in blood lactate concentration; these parameters were determined in 100%, 88%, and 96% of subjects, respectively. The interobserver error among three evaluators was not significant, and LT was correlated with each VT (r=0.97, 0.92;p=0.0001) and with peak\(\dot VO_2 \) (r=0.91;p=0.0001). The VTs were correlated with each other when expressed as milliliter per minute and milliliters per kilogram per minute. It was concluded that a progressive exercise protocol on a treadmill was a feasible procedure for determining the VTs in most individuals and that VTs were valid, useful parameters for evaluating submaximal exercise tolerance in patients with congenital heart disease.
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Ohuchi, H., Nakajima, T., Kawade, M. et al. Measurement and validity of the ventilatory threshold in patients with congenital heart disease. Pediatr Cardiol 17, 7–14 (1996). https://doi.org/10.1007/BF02505805
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DOI: https://doi.org/10.1007/BF02505805