Abstract
A systematic investigation covering a wide diversity of yeast species was made on the appearance of respiratory deficient (petite) mutants after treatment with acriflavine. Petite mutants were obtained from certain species only, but in these species all strains were found to have in common the property of giving rise to petite mutants; such species were designated as “petite positive”. Species failing to give rise to petite mutants were accordingly called “petite negative”. The primary action of acriflavine, namely the inhibition of the synthesis of the respiratory system, was shown to occur not only in petite positive yeasts, but also in petite negative ones. Some implications of the results are discussed.
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Bulder, C.J.E.A. Induction of petite mutation and inhibition of synthesis of respiratory enzymes in various yeasts. Antonie van Leeuwenhoek 30, 1–9 (1964). https://doi.org/10.1007/BF02046695
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DOI: https://doi.org/10.1007/BF02046695