Summary
A carcinoid tumour occurred in the uterine fundus causing an enlargement (12–14 weeks size). The patient did not have the carcinoid syndrome, despite elevated urinary 5-hydroxyindole acetic acid levels. The tumour had a typical organoid pattern with argentaffin-positive cells. Whilst a metastasis from an occult primary lesion cannot be entirely excluded, it is felt that this is a primary tumour most likely arising from resident endocrine cells in the endometrium.
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Albores-Saavedra J, Larraza O, Poucell S, Martinez HAR (1976) Carcinoid of the uterine cervix. Cancer 38:2328–2342
Albores-Saavedra J, Rodriguez-Martinez HA, Larraza-Hernandez O (1979) Carcinoid tumours of the cervix. Pathol Annu 14:273–291
Bannatyne E, Russell P, Willis EJ (1983) Argyrophilia and endometrial carcinoma. Int J Gynecol Pathol 2:235–254
Cheng H, Leblond CP (1974) Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine. III. Endocrine cells. Am J Anat 141:503–520
Fetissof F, Arbeille B, Buchet C, Rigal J, Lansac J (1987) Malignant mixed mesodermal tumour with endocrine cells of the corpus uteri. Ann Pathol 7:311–314
Habib A, Kaneko M, Cohen CJ, Walker J (1979) Carcinoid of the cervix. Cancer 43:535–538
Inoue M, Ueda G, Yamasaki M, Tanaka Y, Hiramatsu K (1984) Immunohistochemical demonstration of peptide hormones in endometrial carcinomas. Cancer 54:2127–2131
Mullins JD, Hilliard GD (1981) Cervical carcinoid (“argyrophil cell” carcinoma) associated with an endocervical carcinoma: a light and ultrastructural study. Cancer 47:785–790
Nogales F (1987) Germ cell tumours of the ovary. In: Fox H (ed) Haines and Taylor Obstetrical and gynaecological pathology. Churchill Livingstone, London, pp 637–675
Satake T, Matsuyama M (1987) Argyrophil cell in normal endometrial glands. Virchows Arch [A] 410:449–454
Scully RE, Agiurre P, DeLellis RA (1984) Argyrophilia, serotonin and peptide hormones in the female genital tract and its tumours. Int J Gynecol Pathol 3:51–70
Vittoria A, Paino G, LaMura E, Budetta G, Cecio A (1989) Chromogranin- and somatostatin-containing neuroendocrine cells in the porcine uterus. An immunocytochemical study. Anat Histol Embryol 18:136–142
Wang T (1989) Human fetal endometrium-light and electron microscopic study. Arch Gynecol Obstet 246:169–179
Wick MR, Stanley M, Cherwitz DL, Savage JE (1986) Concomitant neuropeptide-producing endometrial carcinomas and ileal carcinoid tumors. Am J Clin Pathol 85:406–410
Wilander E, Grimelius L, Lundqvist G, Skoog V (1979) Polypeptide hormones in argentaffin and argyrophil gastroduodenal endocrine tumours. Am J Pathol 96:519–530
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Chetty, R., Clark, S.P. & Bhathal, P.S. Carcinoid tumour of the uterine corpus. Vichows Archiv A Pathol Anat 422, 93–95 (1993). https://doi.org/10.1007/BF01605139
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DOI: https://doi.org/10.1007/BF01605139