Summary
In a prospective, controlled randomized study either lyophilized bovine pericardium or lyophilized human dura mater have been used as a patch for the closure of the dura in 102 patients. The aim of this investigation was to compare both materials in terms of immunogenic response of the patients. The rate of post-operative complications was comparably low in both groups (wound infection in 1/51 patients each). In regard of workability, thicknesss of the material and flexibility the pericardium patches were judged to be by far superior. Neither signs of a cellular nor of an intesified humoral response could be detected in patients who received the pericardium implants. Thus, lyophilized bovine pericardium seems to be a superior alternative for the surgical repair of dural defects.
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References
Axhausen W (1962) Die Bedeutung der Individual-und Art-spezifitÄt der Gewebe für die freie Knochenverpflanzung. Hefte Unfallheilk. 72: 1–117
Campbell JB, Bassett CAL, Robertson JW (1958) Clinical use of freeze-dried human dura mater. J Neurosurg 15: 207–214
Cantore G, Guidetti B, Delfini R (1987) Neurosurgical use of human dura mater sterilized by gamma rays and stored in alcohol: long-term results. J Neurosurg 66: 93–95
Crawford FA, Sade RM, Spinal F (1986) Bovine pericardium for correction of congenital heart-defects. Ann Thorac Surg 41: 602–605
Danielson GK, Downing P, Schaff HV, Puga FJ, DiDonato RM, Ritter DG (1987) Replacement of obstructed extracardiac conduits with autogenous tissue reconstructions. J Thorac Cardiovasc Surg 93: 555–559
Frater RWM, Gabbay S, Shore D, Factor S, Strom J (1983) Reproducable replacement of elongated or ruptured mitral valve chordae. Ann Thorac Surg 35: 14–28
Friedebold G, Sparmann M, Zilch H, Noack W (1987) Carbon fibers and conserved dura. Acta Orthop. Belg 53: 348–352
Gallo JI, Artinano E, Duran CMG (1982) Clinical experience with glutaraldehyde-preserved heterologous pericardium for the closure of the pericardium after open heart surgery. Thorac Cardiovasc Surg 30: 306–309
Jaeger M, Wirth CJ (1977) Transplantation of connective tissue (tendon, cutis, fascia, dura). In: Masshoff JM (ed) Handbuch der allgemeinen Pathologie VI. Springer, Berlin Heidelberg New York Tokyo, 1977
Jarrell MA, Malinin TI, Averette HE, Girtanner RE, Harrison CR, Penalver MA (1987) Human dura mater allografts in repair of pelvic floor and abdominal wall defects. Obstet Gynecol 70: 280–285
Jerusalem C, Jap PHK (1977) General pathology of the transplantation reaction in experimental and clinical organ grafts. In: Masshoff JM (ed) Handbuch der allgemeinen Pathologie VI. Springer, Berling Heidelberg New York Tokyo, pp 439–615
Kulakowski A, Ruka W (1987) Dura mater (Lyodura) in reconstruction of the abdominal and chest wall defects after radical excision of soft tissue neoplasms—case reports. Eur J Surg Oncol 13: 63–68
Lehman RAW, Hayes GJ, Martins AN (1967) The use of adhesive and lyophilized dura in the treatment of cerebrospinal rhinorrhea. J Neurosurg 26: 92–95
Longmire WP, Cannon JA, Weber RA (1954) General surgical problems of tissue transplantation. In: Preservation and transplantation of normal tissue (Ciba Foundation). Churchill, London, p 23
Nageotte J (1927) über die Verpflanzung von abgetöteten Bindegewebestücken. Virchows Arch path Anat 263: 69
Park TS, Delashaw JB, Broaddus WC, Vollmer DG (1985–1986) Lyophilized cadaver dura mater for primary repair of myelomeningoceles. Pediatr Neurosci 12: 315–319
Royce PL, Zimmern PE, de Kernion JB (1988) Patch grafting the renal pelvis and ureteropelvic junction. Urol Res 16: 37–41
Steffen C, Timpl R, Wolff J, Furthmayer H, Wick G (1967) Immunbiologie und Immunpathologie des Kollagens. Melsunger Med Mitt 41: 27
Walker WE, Duncan JM, Frazier OH, Livesay JJ, Ott DA, Reul GJ, Cooley DA (1983) Early experience with the Ionescu-Shiley pericardial xenograft valve. J Thorac Cardiovasc Surg 86: 570–575
Weber KA, Knipping J (1966) Zur Anwendung lyophilisierter Dura in der Chirurgie. Zentralbl Chir 18: 682–689
Weickmann F, Steinke HJ (1959) Deckung gro\er Duradefekte mittels lyophilisierter Fremddura. Chirurg 30: 320–322
Yakirevich VS, Abdulali SA, Abbott CR, Ionescu MI (1984) Reconstruction of the pericardial sac with glutaraldehyde-preserved bovine pericardium. Texas Heart Inst J 11: 238–242
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Laun, A., Tonn, J.C. & Jerusalem, C. Comparative study of lyophilized human dura mater and lyophilized bovine pericardium as dural substitutes in neurosurgery. Acta neurochir 107, 16–21 (1990). https://doi.org/10.1007/BF01402607
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DOI: https://doi.org/10.1007/BF01402607