Summary
Tyromyces sambuceus was cultivated in a stirred tank reactor under semicontinuous conditions for 70 days. Over longer periods of time in submersion, values of 220 and 330 mg·L−1 of 4-decanolide could be maintained; after dispersion of the headspace mycelia, a single peak product concentration of 880 mg·L−1 was attained. The productivity was subject to large variations, peak values were 18 and 11 mg·L−1·h−1. Depending on the culture conditions, specific growth rates of up to 0.05 h−1 were reached.
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Kapfer, G.F., Berger, R.G. & Drawert, F. Production of 4-decanolide by semicontinuous fermentation of Tyromyces sambuceus. Biotechnol Lett 11, 561–566 (1989). https://doi.org/10.1007/BF01040036
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DOI: https://doi.org/10.1007/BF01040036