Abstract
Technetium-99m sulfur colloid (SC) and Technetium-99m pyrophosphate (PYP) scintigrams in a patient with idiopathic systemic amyloidosis were abnormal. Hepatic SC distribution was nonhomogeneous. Spleen showed reduced SC uptake and a large focal defect at its upper pole. Splenic localization of PYP was seen on a bone scan. On histologic examination the abnormal scintigraphic sites showed heavy amyloid deposition. Splenic localization of skeletal radiotracer due to amyloidosis has not been previously reported.
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Rao, B.K., Padmalatha, C., Buchon, J.A. et al. Hepatic and splenic scintigraphy in idiopathic systemic amyloidosis. Eur J Nucl Med 6, 143–146 (1981). https://doi.org/10.1007/BF00253162
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DOI: https://doi.org/10.1007/BF00253162