Summary
Inocula, used for the production of penicillin and griseofulvin, giving different yields, were investigated. Biochemical factors, such as the level of enzyme activity and efficiency, were at least as important as morphology in determining yield, being carried forward from the inoculum to the production stage.
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Smith, G.M., Calam, C.T. Variations in inocula and their influence on the productivity of antibiotic fermentations. Biotechnol Lett 2, 261–266 (1980). https://doi.org/10.1007/BF00239854
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DOI: https://doi.org/10.1007/BF00239854