Abstract
We evaluated a total of 13 cases of Freiberg's disease in patients aged 47–77 years collected over an 8-year period. Seven were associated with diabetes mellitus and one with chronic renal failure; the remainder had no underlying disease. Atrophy of intrinsic small foot muscles secondary to neuropathy, which is prevalent in diabetes mellitus, may play a part in the development of Freiberg's infraction.
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Amano M, Ohsawa S, Saito S, etal. (1990) Multiple osteonecrosis associated with allergic dermatomyositis. Arch Orthop Trauma Surg 109:170
Binek R, Levinsohn EM, Bersani F, et al. (1988) Freiberg's disease complicating unrelated trauma. Orthopedics 11:753
Braddock GTF (1959) Experimental epiphyseal injury and Freiberg's disease. J Bone Joint Surg [Br] 41:154
Cauthier G, Elbaz R (1978) Freiberg's infraction: a subchondral bone fatigue fracture. Clin Orthop 142:93
Cofield RH, Morrison MJ, Beabout TW (1983) Diabetic neuroarthropathy in the foot: patient characteristics and patterns of radiographic change. Foot Ankle 4:15
Freiberg AH (1914) Infraction of the second metatarsal bone. Surg Gynecol Obstet 19:191
Friedman SA, Rakow RB, Brooklyn PD (1990) Osseous lesions of the foot in diabetic neuropathy. Diabetes 20:302
Geoffrey J, Hoeffel TC, Drovin P, etal. (1979) The feet in diabetes. Roentgenographic observation in 1501 cases. Diagnostic Imaging 48:286
Gertner E, Sukenik S, Gladman D, etal. (1990) HLA antigens and nailfold capillary microscopy studies in patients with insulin dependent and non-insulin dependent diabetes mellitus and limited joint mobility. J Rheumatol 17:1375
Gottschalk F, Powell M, Mooney V (1985) Management of the diabetic neurotrophic foot. Cardiovasc Rev Rep 6(11): 1235
Greene DA (1987) Diabetic complications. Somatic neuropathies. Drug Ther 17:91
Hennessy O (1984) Case report 264: diabetic neuropathic disorder with bilateral Lisfranc fracture of feet. Skeletal Radiol 11:155
Mandell GA, Harcke HT (1987) Scintigraphic manifestations of infraction of the second metatarsal (Freiberg's disease). J Nucl Med 28:249
McMaster MJ (1978) The pathogenesis of hallux rigidus. J Bone Joint Surg [Br] 60:82
Newman JH (1979) Spontaneous dislocation in diabetic neuropathy. J Bone Joint Surg [Br] 61:484
Newman JH, Wagner FW (1978) Classification and management of diabetic osteopathy. J Bone Joint Surg [Br] 60:142 (abstr)
Omer GE (1981) Primary articular osteochondroses. Clin Orthop 158:33
Podolsky S (1990) Diabetic complications. The diabetic foot. In: Levin ME. Diabetes mellitus in the elderly. Raven, New York
Pogonowska MJ, Collins LC, Dobson HL (1967) Diabetic osteopathy. Radiology 89:265
Reinhardt K (1981) The radiological residue of healed diabetic arthopathies. Skeletal Radiol 7:167
Resnick D, Niwayama G (1988) Diagnosis of joint and bone disorders, 2nd edn. W.B. Saunders, Philadelphia
Riddle M (1990) Diabetic neuropathies in the elderly: management update. Geriatrics 45:32
Resnick D, Pinepa C, Trudell D (1985) Widespread osteonecrosis of the foot in systemic lupus erythematosus: radiographic and gross pathologic correlation. Skeletal Radiol 13:33
Scartozzi G, Schram A, Janigian T (1989) Freiberg's infraction of the second metatarsal head with formation of multiple loose bodies. J Foot Surg 28:195
Smillie IS (1967) Treatment of Freiberg's infraction. Proc R Soc Lond 60:29
Stanley D, Betts RP, Rowley DI, etal. (1990) Assessment of etiologic factors in the development of Freiberg's disease. J Foot Surg 29:444
Trott AW (1982) Developmental disorders. In: Jahss MH (ed) Disorders of the foot, vol 1. W.B. Saunders, Philadelphia
Walsh HPJ, Dorgan JC (1988) Etiology of Freiberg's disease: trauma. J Foot Surg 27:243
Wiley JJ, Thurston P (1981) Freiberg's disease. J Bone Joint Surg [Br] 63:459
Young JR (1988) Foot problems in diabetic patients. Cleveland Clinic J Med 55:458
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Nguyen, V.D., Keh, R.A. & Daehler, R.W. Freiberg's disease in diabetes mellitus. Skeletal Radiol. 20, 425–428 (1991). https://doi.org/10.1007/BF00191084
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DOI: https://doi.org/10.1007/BF00191084