Dupuytren’s Disease

Abstract

Dupuytren’s disease is a common disease of the hand and fingers. Specific fascial structures are involved in the disease process. Mild forms of the disease may be monitored, while more severe forms inhibiting function require intervention. Surgical intervention is often required.

What cells play a primary role in Dupuytren’s disease?	Myofibroblasts
What two fingers are most commonly involved with Dupuytren’s disease?	Small and ring fingers
What physical exam test can be used to determine severity of Dupuytren’s disease?	Palm to table test
What type of enzyme may be injected to treat Dupuytren’s disease?	Collagenase
Contracture of what tissue is the cause of Dupuytren’s disease?	Fascia
Fascial bands become cords in Dupuytren’s disease. What cords may develop?	Pretendinous cord, spiral cord, natatory cord, retrovascular cord
The spiral cord causes the neurovascular bundle to displace in what direction?	Centrally and superficial to the A-1 pulley
What is the most common surgical treatment for Dupuytren’s disease?	Fasciectomy
What is the most common complication of Dupuytren’s surgical excision?	Wound edge necrosis, hematoma formation
In Dupuytren’s disease, the thickening of tissue on the dorsum of the PIP joints is known as what?	Garrod’s pads (knuckle pads)