Abstract
History and clinical examination are the main tools of clinical dermatologists. Inspection of the skin is rapid, and the lateral extension and severity of a dermatitis is easily assessed. The disadvantage is that this method is essentially subjective. As a research tool it is open to bias and thus difficult to use. With punch biopsy and microscopy, detailed information about the layers of the skin and their involvement with dermatitis is obtained; however, a punch usually represents only a very small fraction of diseased skin, and processing and staining are a kind of desirable artefact. The result still has a subjective element, related to the pathologist’s examination.
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Serup, J. (1995). Noninvasive Techniques for Quantification of Contact Dermatitis. In: Rycroft, R.J.G., Menné, T., Frosch, P.J. (eds) Textbook of Contact Dermatitis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-03104-9_19
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DOI: https://doi.org/10.1007/978-3-662-03104-9_19
Publisher Name: Springer, Berlin, Heidelberg
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