Abstract
How each microRNA regulates gene expression is unknown problem. Especially, which gene is targeted by each microRNA is mainly depicted via computational method, typically without biological/ experimental validations. In this paper, we propose a computational method to detect gene expression regulation via miRNAs by the use of expression profile data and miRNA target prediction. This method is tested to miRNA transfection experiments to tumor cells and succeeded in inference of transfected miRNA.
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Taguchi, Yh., Yasuda, J. (2010). Inference of Gene Expression Regulation via microRNA Transfection. In: Huang, DS., Zhao, Z., Bevilacqua, V., Figueroa, J.C. (eds) Advanced Intelligent Computing Theories and Applications. ICIC 2010. Lecture Notes in Computer Science, vol 6215. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-14922-1_84
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DOI: https://doi.org/10.1007/978-3-642-14922-1_84
Publisher Name: Springer, Berlin, Heidelberg
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