Control of Biofilm Infections by Signal Manipulation
Overview
- Editors:
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Naomi Balaban
- Provides novel approaches and solutions to biofilm infections that are largly untreatable by using conventional approaches and antibiotics
- Includes supplementary material: sn.pub/extras
About this book
In the well-watered groves of academe, most of us are content to gather worshipful students and technicians in a shady nook to contemplate the eternal verities and to plan extravagant feasts to celebrate our contributions to “knowledge” and to the gradual improvement of the human condition. As one convocation follows another, and as our funding agencies pump billions of dollars into incremental research that ?lls every possible pigeon-hole in which a gene makes a protein, a small number of intellectual athletes seize a pivotal concept and plunge into the real world. It is this small band of nimble and impossibly brave intellectual halfbackswho win gamesin the real world, and this book is the result of the drive and intellectual athleticism of its editor and several of her contributors. Bacteria affect humans more than any other life forms with which we share the blue planet, but our understandingof these invisible companionshas developed in a staggering pattern, crippled by our panic and consequent shifts of emphasis. When our race was threatened by epidemic diseases, we visualized bacteria as swarms of potentially lethal planktoniccells from which we must remain isolated by sanitation and which we had to kill by immunization and chemical antibacterial compounds. By the time this overriding threat had been obviated, we began to examine na- ral and pathogenic ecosystems by direct methods, and we were surprised to ?nd that planktonic bacteria are comparatively rare and that most prokaryotes grow in matrix-enclosedbio?lms.
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Article
Open access
21 August 2015
Article
16 September 2015
Table of contents (10 chapters)
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Front Matter
Pages ii-xvi
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- Naomi Balaban, Dacheng Ren, Michael Givskov, Thomas Bovbjerg Rasmussen
Pages 1-11
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- Michael Givskov, Thomas Bovbjerg Rasmussen, Dacheng Ren, Naomi Balaban
Pages 13-38
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- Robert J.C. McLean, Sandra A. Bryant, Dhiraj A. Vattem, Michael Givskov, Thomas Bovbjerg Rasmussen, Naomi Balaban
Pages 39-50
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- Dacheng Ren, Michael Givskov, Thomas Bovbjerg Rasmussen, Naomi Balaban
Pages 51-77
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- Naomi Balaban, Michael Givskov, Thomas Bovbjerg Rasmussen, Andrea Giacometti, Oscar Cirioni
Pages 109-117
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- Naomi Balaban, Michael Givskov, Thomas Bovbjerg Rasmussen
Pages 119-129
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- M. Dilani Senadheera, Fengxia Qi, Dennis Cvitkovitch
Pages 131-140
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- E. Peter Greenberg, Ehud Banin
Pages 141-156
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Back Matter
Pages 171-175