Abstract
The host cells and the events in the cells during Torque teno (TT) virus infection are at present unknown. Replicating TT virus DNA has been detected in liver, in peripheral blood mononuclear cells (PBMC), and in bone marrow. By alternative splicing this small virus generates three mRNA species, from which by alternative translation initiation at least six proteins are produced. The functions of the proteins are not yet fully understood. However, functions associated with, e.g., DNA replication, immunomodulation, and apoptosis have been suggested to reside in the multifunctional proteins of anelloviruses.
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Keywords
- Peripheral Blood Mononuclear Cell
- Torque Teno Virus
- ORF2 Protein
- Chicken Anemia Virus
- Alternative Translation Initiation
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Kakkola, L., Hedman, K., Qiu, J., Pintel, D., S”derlund-Venermo, M. (2009). Replication of and Protein Synthesis by TT Viruses. In: de Villiers, EM., Hausen, H.z. (eds) TT Viruses. Current Topics in Microbiology and Immunology, vol 331. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-70972-5_4
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DOI: https://doi.org/10.1007/978-3-540-70972-5_4
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