Abstract
The underlying principles of nuclear medicine imaging involve the use of unsealed sources of radioactivity which are administered in the form of radiopharmaceuticals; the ionizing radiations which accompany the decay of the administered radioactivity can be detected and measured with specially designed instruments (e.g., survey meters, gamma cameras). In order to appreciate the scientific and technical basis of nuclear medicine imaging, this chapter reviews atomic and nuclear structure, radioactivity and radioactive decay, and interactions of radiation with matter. This is followed by a discussion of techniques for detection and measurement of radiation, design and operating principles of detection and imaging instruments, instrument quality control, and radiation protection.
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Keywords
- Count Rate
- Gamma Camera
- Positron Emission Tomography Scanner
- National Electrical Manufacturer Association
- National Electrical Manufacturer Association
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Further Reading
Bendriem B, Townsend DW (eds) (1998) The theory and practice of 3D PET. Kluwer Academic, Dordrecht
Cherry SR, Sorenson JA, Phelps ME (2003) Physics in nuclear medicine, 3rd edn. Saunders, Philadelphia, PA, pp 325–359
Zanzonico PB (1995) Technical requirements for SPECT: Equipment and quality control. In: Kramer EL, Sanger JJ (eds) Clinical applications in SPECT. Raven Press, New York, pp 7–41
Zanzonico P (2000) Internal radionuclide radiation dosimetry: A review of basic concepts and recent developments. J Nucl Med 41:297–308
Zanzonio P (2002) The intraoperative probe: design, operation, and safety. In: Cody HS III (ed) Sentinel node biopsy. Martin Dunitz, London
Zanzonico P (2004) Positron emission tomography: A review of basic principles, scanner design and performance, and current systems. Semin Nucl Med 34:87–111
Zanzonico P, Heller S (2000) The intraoperative gamma probe: Basic principles and choices available. Semin Nucl Med 30:33–48
Zanzonico P, Siegel J, St Germain J (2000) A generalized algorithm for determining the time of release and the duration of post-release radiation precautions following radionuclide therapy. Health Phys 6:648–659
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© 2007 Springer-Verlag Berlin Heidelberg
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Zanzonico, P., Heller, S. (2007). Physics, Instrumentation, and Radiation Protection. In: Biersack, HJ., Freeman, L.M. (eds) Clinical Nuclear Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-28026-2_1
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DOI: https://doi.org/10.1007/978-3-540-28026-2_1
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-28025-5
Online ISBN: 978-3-540-28026-2
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