Abstract
The purpose of the auditory brainstem implant (ABI) is to directly stimulate the cochlear nucleus complex and offer restoration of hearing in patients suffering from profound retrocochlear sensorineural hearing loss. Electrical stimulation of the auditory pathway via an ABI has been proven to be a safe and effective procedure. The function of current ABIs is similar to that of cochlear implants in terms of device hardware with the exception of the electrode array and the sound-signal processing mechanism. The main limitation of ABI is that electrical stimulation is performed on the surface of the cochlear nuclei, thereby making impractical the selective activation of deeper layers by corresponding optimal frequencies. In this article, we review the anatomical, and experimental basis of ABIs and the indications, and surgical technique for their implantation. To the best of our knowledge, we describe the first pathology images of the cochlear nucleus in a patient who had received an ABI.
Access provided by Autonomous University of Puebla. Download to read the full chapter text
Chapter PDF
Similar content being viewed by others
References
Brackmann D, Hitselberger WE, Nelson RA, Moore J, Waring MD, Portillo F, Shannon RV, Telischi FF (1993) Auditory brainstem implant: I. issues in surgical implantation. Otolaryngol Head Neck Surg 108: 624–633
Cant NB, Benson CG (2003) Parallel auditory pathways: projection patterns of the different neuronal populations in the dorsal and ventral cochlear nuclei. Brain Res Bull 60: 457–474
Cervera-Paz FJ (2001) Los núcleos cocleares del primate Macaca fascicularis. Citoarquitectura normal y efectos de la sección bilateral del nervio coclear. University of Navarra, Thesis
Colletti V, Fiorino FG, Carner M, Miorelli V, Guida M, Colletti L (2004) Auditory brainstem implant as a salvage treatment after unsuccessful cochlear implantation. Otol Neurotol 25: 485–496
Colletti V, Shannon RV (2005) Open set speech perception with auditory brainstem implant? Laryngoscope 115: 1974–1978
Colletti V, Carner M, Fiorino F, Sacchetto L, Miorelli V, Orsi A, Cilurzo F, Pacini L (2002) Hearing restoration with auditory brainstem implant in three children with cochlear nerve aplasia. Otol Neurotol 23: 682–693
Frohne C, Matthies C, Lesinki-Schiedat A, Battmer RD, Lenarz T (2000) Extensive monitoring during auditory brainstem implant surgery. J Laryngol Otol 114Suppl 27: 11–14
Grayeli AB, Bouccara D, Kalamarides M, Ambert-Dahan E, Coudert C, Cyna-Gorse F, Sollmann WP, Rey A, Sterkers O (2003) Auditory brainstem implant in bilateral and completely ossified cochleae. Otol Neurotol 24: 79–82
Green JD, Marion MS, Hinojosa R (1991) Labirinthitis ossificans: histopathologic consideration for cochlear implantation. Otolaryngol Head Neck Surg 104: 320–326
Hitselberger W, House WF, Edgerton BJ, Whitaker S (1984) Cochlear nucleus implant. Otolaryngol Head Neck Surg 92: 52–54
Insausti AM, Cruz-Orive LM, Jaúregui I, Manrique M, Insausti R (1999) Stereological assessment of the glial reaction to chronic deafferentation of the cochlear nuclei in the macaque monkey (M. fascicularis). J Comp Neurol 414: 485–494
Insausti AM, Insausti R, Cruz-Orive LM, Manrique M (2000) Stereological analysis of the cochlear nuclei of monkey (Macaca fascicularis) after deafferentation. Image Anal Stereol 19: 133–137
Kalamarides M, Grayeli AB, Bouccara D, Dahan EA, Sollmann WP, Sterkers O, Rey A (2001) Hearing restoration with auditory brainstem implants after radiosurgery for neurofibromatosis type 2. J Neurosurg 95: 1028–1033
Kaltenbach JA, Melica RJ, Falzarano PR (1996) Alterations in the tonotopic map of the cochlear nucleus following cochlear damage. In: Salvi J et al (eds) Auditory system plasticity and regeneration. Thieme Medical Publishers, New York, pp 317–332
Kanowitz SJ, Shapiro WH, Golfinos JG, Cohen NL, Roland JT Jr (2004) Auditory brainstem implantation in patients with neurofibromatosis type 2. Laryngoscope 114: 2135–2146
Kuchta J (2004) Neuroprosthetic hearing with auditory brainstem implants. Biomed Tech (Berl) 49: 83–87
Laszig R, Kuzma J, Seifert V, Lehnhardt E (1991) The Hannover auditory brainstem implant: a multiple-electrode prosthesis. Eur Arch Otorhinolaryngol 248: 420–421
Leake PA, Snyder RL, Hradek GT (2002) Postnatal refinement of auditory nerve projections to the cochlear nucleus in cats. J Comp Neurol 448: 6–27
Liu X, McPhee G, Seldon HL, Clark GM (1997) Acute study on the neuronal excitability of the cochlear nuclei of the guinea pig following electrical stimulation. Acta Otolaryngol 117: 363–375
Liu X, McPhee G, Seldon HL, Clark GM (1997) Histological and physiological effects of the central auditory prosthesis: surface versus penetrating electrodes. Hear Res 114: 264–274
Manrique M, Cervera-Paz FJ, Jaúregui I, Vanaclocha V, Pérez N (2000) Auditory brainstem implantation in primates: lessons learned for human surgery and application. J Laryngol Otol Suppl 27: 18–22
Manrique M, Jauregui I, Insausti A, Insausti R, Cervera-Paz FJ, Perez N, Vanaclocha V (2000) Experimental study following inactive implantation of an auditory brainstem implant in nonhuman primates. Ann Otol Rhinol Laryngol 109: 163–169
Manrique M (2001) New perspectives in auditory brainstem stimulation with penetrating electrodes. 3rd International symposium on auditory brainstem implant. Freiburg, Germany
Manrique M (2003) Penetrating electrodes for auditory brainstem implant. 4th International symposium on electronic implants in otology and conventional hearing aids. Tolouse, France
McCreery DB, Shannon RV, Moore JK, Chatterjee M (1998) Accessing the tonotopic organization of the ventral cochlear nucleus by intranuclear microstimulation. IEEE Trans Rehabil Eng 6: 391–399
McElveen JT, Hitselberger WE, House WF (1987) Surgical accessibility of the cochlear complex in man: surgical landmarks. Otolaryng Head Neck 96: 135–140
Nevison B, Laszig R, Sollmann WP, Lenarz T, Sterkers O, Ramsden R, Fraysse B, Manrique M, Rask-Andersen H, Garcia-Ibanez E, Colletti V, von Wallenberg E (2002) Results from a European clinical investigation of the nucleus multichannel auditory brainstem implant. Ear Hear 23: 170–183
Ni D, Seldon HL, Shepherd RK, Clark GM (1993) Effect of chronic electrical stimulation on cochlear nucleus neuron size in normal hearing kittens. Acta Otolaryngol 113: 489–497
Niparko JK, Altschuler RA, Xue XL, Wiler JA, Anderson DJ (1989) Surgical implantation and biocompatibility of central nervous system auditory prostheses. Ann Otol Rhinol Laryngol 98: 965–970
Otto SR, Brackmann DE, Hitselberger W (2004) Auditory brainstem implantation in 12-to 18-year-olds. Arch Otolaryngol Head Neck Surg 130: 656–659
Ramsden RT (2002) Cochlear implants and brain stem implants. Br Med Bull 63: 183–193
Rauschecker JP, Shannon RV (2002) Sending sound to the brain. Science 8:295: 1025–1029
Shannon RV (2004) Psychophysical and speech results from the first patients with the penetrating auditory brainstem implant (PABI). VIII International cochlear implant conference. Indianapolis, USA
Wu H, Kalamarides M, Bouccara D, Dahan EA, Viala P, Sollmann WP, Rey A, Sterkers O (2000) Auditory brainstem implant (Nucleus 21-channel) in neurofibromatosis type 2 patients previously operated on: preliminary results. Adv Otorhinolaryngol 57: 236–239
Yuen TGH, Agnew WF, Bullara LA, Jacques S, McCreery DB (1981) Histological evaluation of neural damage from electrical stimulation: considerations for the selection of parameters for clinical application. Neurosurgery 9: 292–299
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2007 Springer-Verlag/Wien
About this chapter
Cite this chapter
Cervera-Paz, F.J., Manrique, M.J. (2007). Auditory brainstem implants: past, present and future prospects. In: Sakas, D.E., Simpson, B.A. (eds) Operative Neuromodulation. Acta Neurochirurgica Supplements, vol 97/2. Springer, Vienna. https://doi.org/10.1007/978-3-211-33081-4_50
Download citation
DOI: https://doi.org/10.1007/978-3-211-33081-4_50
Publisher Name: Springer, Vienna
Print ISBN: 978-3-211-33080-7
Online ISBN: 978-3-211-33081-4
eBook Packages: MedicineMedicine (R0)