Abstract
A review is provided of contact-printing technologies for the fabrication of planar protein microarrays. The key printing performance parameters for creating protein arrays are reviewed. Solid pin and quill pin technologies are described and their strengths and weaknesses compared.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
References
Ramachandran, N., Hainsworth, E., Bhullar, B., Eisenstein, S., Rosen, B., Lau, AY., Walter, J. C., LaBaer, J. (2004) Self-assembling protein microarrays, Science, Jul 2, 305(5680), 86–90.
Schena, M., Shalon, D., Davis, R. W., Brown, P. O. (1995) Quantitative monitoring of gene expression with a complementary-cDNA microarray, Science, Vol. 270, Page 467–470.
Schena, M., Shalon, D., Heller, R., Chai, A., Davis, R. (1996) Parallel human genome analysis: microarray-based expression monitoring of 1000 genes, PNAS, Oct 1, Vol. 93, No. 20, 10614–10619.
Brown, P., Botstein, D., Exploring the new world of the genome with DNA microarrays, Nat. Genet. Suppl., 21:33–37.
Cheung, V., Morley, M., Aguilar, F., Massimi, A., Kucherlapati, R., Childs, G., Making and reading microarrays, Nat. Genet. (Suppl.), 21:15–19.
Brown, P., Shalon, D., Methods of fabricating microarrays of biological substances, (1998), U.S. Patent 5,807,522.
Available at the Brown Lab website at Stanford: cmgm.stanford.edu/pbrown/mguide/index.html.
Aushon BioSystems website: www.aushon.com
Aushon BioSystems website: http://www.aushon.com/2470-Arrayer.php.
Schena, M. (editor), Microarray Biochip technology, (2000), Eaton Publishing; ISBN 1-88299-37-6.
Hitachi Software Engineering America website: http://www.miraibio.com/download-document/spbio-ii-spotting-pin-evaporation-1.html.
Mundinger, G., Espina, V., Liotta, L., Petricoin, E., Clinical phosphoproteomic profiling for personalized targeted medicine using reverse phase protein microarrays, (2006) Targ. Oncol., DOI 10.1007/s11523-006-0025-2, Springer-Verlag.
Wulfkuhle, J., Edmiston, K., Liotta, L., Petricoin, E. (2006) Technology Insight: pharmacoproteomics for cancer – promises of patient-tailored medicine using protein microarrays, Nature Clinical Practice – Onocology, May, Vol 3, No 5.
Nishizuka, S., Spurrier, B., Honkanen, P., Austin, J., Wakabayashi, G. (2008) Application of quantitative proteomic analysis for cancer therapy using “reverse-phase” protein lysate microarrays, Cancer & Chemotherapy, 35(2):200–5.
Nishizuka, S., Spurrier, B. (2008) Experimental validation for quantitative protein network models, Current Opinion in Biotechnology,19(1):41–9.
Spurrier, B., Honkanen, P., Holway, A., Kumamoto, K., Terashima, M., Takenoshita, S., Wakabayashi, G., Austin, J., Nishizuka, S. (2008) Protein and lysate array technologies in cancer research, Biotechnology Advances, 26(4):361–9.
Spurrier, B., Ramalingam, S., Nishizuka, S. (2008) Reverse-phase protein lysate microarrays for cell signaling analysis, Nature Protocols 3, 1796–1808.
Array-It Corporation website: http://arrayit.com/
Parallel Synthesis website: http://www.parallel-synthesis.com/.
Gulati, R. (2004) Testing and establishing optimal protein array conditions to be applied towards the DARPP-32 Phosphoprotein model system, University of New Haven, MD 690, Research Project, Spring.
LabNext website: http://www.labnext.com/xtend_MP_microarray_pins.htm.
Clark, S., Hamilton, G., Nordmeyer, R., Uber, D., Cornell, E., Brown, N., Segraves, R., Davis, R., Albertson, D., Pinkel, D. (2008) High-efficiency microarray printer using fused-silica capillary tube printing pins, Analytical Chemistry, 80(19):7639–42.
NanoInk website: http://www.nanoink.net/.
Taha, H. et al. (2003) Protein printing with an atomic force sensing nanofountainpen, Applied Physics Letters, Volume 83, 1041–1043.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2011 Springer Science+Business Media, LLC
About this protocol
Cite this protocol
Austin, J., Holway, A.H. (2011). Contact Printing of Protein Microarrays. In: Korf, U. (eds) Protein Microarrays. Methods in Molecular Biology, vol 785. Humana Press. https://doi.org/10.1007/978-1-61779-286-1_25
Download citation
DOI: https://doi.org/10.1007/978-1-61779-286-1_25
Published:
Publisher Name: Humana Press
Print ISBN: 978-1-61779-285-4
Online ISBN: 978-1-61779-286-1
eBook Packages: Springer Protocols