Overview
- Editors:
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Kewal K. Jain
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Jain PharmaBiotech, Basel, Switzerland
- Contains important drug discovery information
- Concise reference for pharmaceutical physicians and scientists
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About this book
Drug delivery systems (DDS) are an important component of drug development and therapeutics. The field is quite extensive and requires an encyclopedia to describe all the technologies. The aim of this book is to put together descriptions of important selective technologies used in DDS. Important drugs, new technologies such as nanoparticles, as well as important therapeutic applications, are taken into consideration in this selection. This book will be an important source of information for pharmaceutical scientists and pharmacologists working in the academia as well as in the industry. It has useful information for pharmaceutical physicians and scientists in many disciplines involved in developing DDS such as chemical engineering, protein engineering, gene therap y, and so on. This will be an important reference for executives in charge of research and development at several hundred companies that are developing drug delivery technologies. Kewal K. Jain, MD v Contents Preface. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . v Contributors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ix 1 Drug Delivery Systems – An Overview. . . . . . . . . . . . . . . . . . . . . . . . . . 1 Kewal K. Jain 2 The Role of the Adeno-Associated Virus Capsid in Gene Transfer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 51 Kim M. Van Vliet, Veronique Blouin, Nicole Brument, Mavis Agbandje-McKenna, and Richard O. Snyder 3 Delivering Small Interfering RNA for Novel Therapeutics . . . . . . . . . 93 Patrick Y. Lu and Martin C. Woodle 4 Catheters for Chronic Administration of Drugs into Brain Tissue. . . . . . . . . . . . . . . . . . . . . . . . . .. . . . . . . . . . . . . . . . . . 109 Michael Guarnieri, Benjamin S. Carson, Sr. , and George I. Jallo 5 T ransdermal Drug Delivery Systems: Skin Perturbation Devices . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 119 Marc B. Brown, Matthew J. Traynor, Gary P. Martin, and Franklin K.
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Table of contents (11 protocols)
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- Kim M. Van Vliet, Veronique Blouin, Nicole Brument, Mavis Agbandje-McKenna, Richard O. Snyder
Pages 51-91
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- Patrick Y. Lu, Martin C. Woodle
Pages 93-107
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- Michael Guarnieri, Benjamin S. Carson Sr, George I. Jallo
Pages 109-117
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- Marc B. Brown, Matthew J. Traynor, Gary P. Martin, Franklin K. Akomeah
Pages 119-139
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- Pieter J. Gaillard, Albertus G. de Boer
Pages 161-175
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- Youqing Shen, Huadong Tang, Maciej Radosz, Edward Van Kirk, William J. Murdoch
Pages 183-216
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- Sandip B. Tiwari, Ali R. Rajabi-Siahboomi
Pages 217-243
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Back Matter
Pages 245-251
Reviews
"... a powerful reference that provides concise and systematic description of drug delivery technologies ..." - Doody's Book Review
Editors and Affiliations
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Jain PharmaBiotech, Basel, Switzerland
Kewal K. Jain