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Brain Metabolic and Vascular Adaptations to Hypoxia in the Rat

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Oxygen Transport to Tissue XIX

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 428))

Abstract

Prolonged exposure to low oxygen environments provokes systemic adaptations that result in maintained oxygen delivery to the brain, and central cerebrovascular and metabolic adaptations that preserve tissue oxygen and energy supply to support neuronal function. Recently, we have examined a number of aspects of the central nervous system adaptation to mild hypoxia, and though these studies provide a far from complete understanding of the phenomenon, some general conclusions can at least be drawn.

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© 1997 Springer Science+Business Media New York

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La Manna, J.C., Harik, S.I. (1997). Brain Metabolic and Vascular Adaptations to Hypoxia in the Rat. In: Harrison, D.K., Delpy, D.T. (eds) Oxygen Transport to Tissue XIX. Advances in Experimental Medicine and Biology, vol 428. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5399-1_23

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  • DOI: https://doi.org/10.1007/978-1-4615-5399-1_23

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-7465-7

  • Online ISBN: 978-1-4615-5399-1

  • eBook Packages: Springer Book Archive

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