Abstract
Taurine, a sulfur containing ß-amino acid, is present in high concentrations in most mammalian tissues. Although taurine is not a constituent of mammalian proteins, it plays an important role in the pathophysiology of cardiovascular and nervous systems1,2 and conjugation of bile acids3. The beneficial effects of taurine against oxidant-induced tissue injury have been attributed to its ability to stabilize biomembranes4,5 and scavenge reactive oxygen species (ROS) including hypochlorous acid6–8. Several effects of taurine on the cardiovascular and central nervous systems may be related to calcium redistribution since taurine alters calcium transport9,10. It has been demonstrated that exogenously administered taurine would offer protection against oxidant-induced lung damage11,12 In addition, Nakashima et a1.13 reported therapeutic and prophylactic effects of taurine on experimentally-induced liver injury.
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Giri, S.N., Wang, Q. (1992). Taurine and Niacin Offer a Novel Therapeutic Modality in Prevention of Chemically-Induced Pulmonary Fibrosis in Hamsters. In: Lombardini, J.B., Schaffer, S.W., Azuma, J. (eds) Taurine. Advances in Experimental Medicine and Biology, vol 315. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-3436-5_39
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DOI: https://doi.org/10.1007/978-1-4615-3436-5_39
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