Abstract
Taurine has been reported to induce a positive inotropy in heart muscle [1–3]. Taurine was also reported to exhibit beneficial effects in the treatment of congestive heart failure [4], and to have protective effects against calcium overload [5,6] and cardiomyopathy [7,8]. Recently, Sperelakis and colleagues reported that taurine also exerts a positive inotropic effect in the perfused embryonic (20-day-old) chick heart, without greatly affecting the slow Ca2+ action potentials accompanying the contractions. They suggested that the positive inotropic effect of taurine was not mediated through an increase in the slow inward Ca2+ current.
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References
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© 1989 Kluwer Academic Publishers, Boston/Dordrecht/London
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Sperelakis, N., Yamamoto, T., Bkaily, G., Sada, H., Sawamura, A., Azuma, J. (1989). Taurine Effects on Action Potentials and Ionic Currents in Chick Myocardial Cells. In: Iwata, H., Lombardini, J.B., Segawa, T. (eds) Taurine and the Heart. Developments in Cardiovascular Medicine, vol 93. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1647-3_1
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DOI: https://doi.org/10.1007/978-1-4613-1647-3_1
Publisher Name: Springer, Boston, MA
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