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Immunologic Aspects of Human Trichomoniasis

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Trichomonads Parasitic in Humans

Abstract

This is a good time to be writing this chapter. The study of human trichomonads has gone through many phases since they were first described over a century ago, and much has been achieved. The three well-established species, Trichomonas vaginalis, Trichomonas tenax, and Pentatrichomonas hominis, are defined and their nomenclature finally settled. Trichomonas vaginalis is accepted as the genuine cause of a common and sometimes serious sexually transmissible disease; reliable diagnostic methods and effective treatments are widely available. All this was true 8 years ago and yet, writing then, we stated that “it cannot really be claimed that the study of the immunology of T. vaginalis is in a particularly fruitful phase, and this may well be the cause of the recent decline in published work on the subject.”1 An enormous amount of work had been done, mainly with the aim of developing serodiagnostic tests, but there was a feeling that progress had come to a halt—and at a very frustrating point where the tests worked but not quite well enough to be clinically useful. In the last 10 years, however, the whole picture has changed, with the explosion of new immunologic and molecular biologic techniques allowing new problems to be tackled and old ones taken up again. I hope that some of the excitement now pervading the field will come through what is, inevitably, still an account based mainly on older results; but there is no doubt that in another 10 years the whole subject will have changed beyond all recognition.

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  1. J. P. Ackers
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Editors and Affiliations

  1. Center for Parasitology Department of Zoology, University of Massachusetts, 01003, Amherst, MA, USA

    B. M. Honigberg PhD (Professor) (Professor)

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Ackers, J.P. (1990). Immunologic Aspects of Human Trichomoniasis. In: Honigberg, B.M. (eds) Trichomonads Parasitic in Humans. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-3224-7_4

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  • DOI: https://doi.org/10.1007/978-1-4612-3224-7_4

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