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Structure of Collagen

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Fibrous Proteins

Part of the book series: Methods in Molecular Biology ((MIMB,volume 2347))

Abstract

Collagen is the most abundant fibrous protein in nature and widely exists in tissues such as connective tissue, tendon, skin, bone, and cartilage. On the one hand, collagen provides mechanical support in tissues, and on the other hand, plays an important role in controlling cell adhesion, cell migration, and tissue repair. A systematic understanding of the structure of collagen can promote the understanding of the biological functions of collagen scaffolds, and also provide theoretical guidance for applications of these natural fibrous protein materials. Therefore, this chapter centers on introducing the structure of collagen. As collagen has a typical hierarchical structure, the introduction to its structure will also be divided into different structural levels, from primary structure to quaternary structure. Due to the diversity of collagen types, this chapter will mainly focus on type I collagen.

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Acknowledgments

This work was supported by the National Natural Science Foundation of China [grant numbers. 51973116, U1832109, 21935002], the Users with Excellence Program of Hefei Science Center CAS [grant number 2019HSC-UE003], the starting grant of ShanghaiTech University, and State Key Laboratory for Modification of Chemical Fibers and Polymer Materials.

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Authors and Affiliations

  1. School of Physical Science and Technology, ShanghaiTech University, Shanghai, China

    Chenxi Zhao, Shengjie Ling & Jing Ren

  2. School of Materials Science and Engineering, Zhengzhou University, Zhengzhou, China

    Yuelong Xiao & Ying Pei

Authors
  1. Chenxi Zhao
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  2. Yuelong Xiao
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  3. Shengjie Ling
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  4. Ying Pei
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  5. Jing Ren
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Corresponding author

Correspondence to Jing Ren .

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Editors and Affiliations

  1. School of Physical Science and Technology, ShanghaiTech University, Shanghai, China

    Shengjie Ling

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Zhao, C., Xiao, Y., Ling, S., Pei, Y., Ren, J. (2021). Structure of Collagen. In: Ling, S. (eds) Fibrous Proteins. Methods in Molecular Biology, vol 2347. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-1574-4_2

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  • DOI: https://doi.org/10.1007/978-1-0716-1574-4_2

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  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-0716-1573-7

  • Online ISBN: 978-1-0716-1574-4

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