Collection

Adverse Radiation Effects in Neuro-Oncology

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Radiation therapy and radiosurgery are key treatment strategies used for patients with primary and secondary neoplasms of the central nervous system (CNS). Although its use is integral to the treatment paradigms in those with benign and malignant disease, recent advances have further elucidated key details to help further tailor and personalize ionizing radiation approaches. To this end, this special issue will review key topics in patients treated with brain and spine stereotactic radiosurgery and fractionated radiotherapy, with a focus on recent evidence, including the diagnosis and management of radiation necrosis, evaluation of post-treatment imaging including white matter changes and pseudoprogression, review of the impact of radiation dosimetry on neurocognition, and analysis of advanced imaging features in radiation injury. Moreover, unique topics will also be discussed including the effects of particle therapy on the brain, radiosurgery in eloquent areas, and pediatrics effects of radiotherapy. Together, this collection is a comprehensive, evidenced-based, and modern review of the published literature regarding the effects of radiotherapy on the brain and spinal cord.

Editors

  • Daniel M. Trifiletti, MD Daniel M. Trifiletti, MD , 

    Daniel M. Trifiletti, MD

    As an international leader in radiation oncology and stereotactic radiosurgery, the research of Daniel M. Trifiletti, M.D., includes numerous clinical studies involving radiation, surgery and drug therapies in the treatment of tumors.

  • Rupesh Kotecha, M.D. Rupesh Kotecha, M.D.  &

    Rupesh Kotecha, M.D.

    Rupesh Kotecha, M.D., is a board-certified radiation oncologist and Chief of Radiosurgery in the Department of Radiation Oncology and Director of the Central Nervous System (CNS) Metastasis program at Miami Cancer Institute. He is an associate professor in the departments of radiation oncology and translational medicine at the FIU Herbert Wertheim College of Medicine.

  • Joshua D. Palmer, MD Joshua D. Palmer, MD

    Joshua D. Palmer, MD

    Dr. Joshua D. Palmer is a radiation oncologist in Columbus, Ohio and is affiliated with multiple hospitals in the area, including Ohio State University Wexner Medical Center and James Cancer Hospital and Solove Research Institute. He received his medical degree from University of Miami Leonard M. Miller School of Medicine and has been in practice between 6-10 years.

Articles (5 in this collection)