Collection
Protein-protein interactions
- Submission status
- Open
- Open for submission from
- 01 January 2021
- Submission deadline
- Ongoing
The following articles were selected by the editors as some of the best research recently published in Medicinal Chemistry Research on protein-protein interactions. This list is current to 1 October, 2023.
Articles (13 in this collection)
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Targeting MDM2 for the development of a new cancer therapy: progress and challenges
Authors
- Angelo Aguilar
- Junius E. Thomas
- Shaomeng Wang
- Content type: Review Article
- Published: 23 June 2023
- Pages: 1334 - 1344
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Design, synthesis, and structure–activity relationships of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid derivatives as inhibitors of the programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) immune checkpoint pathway
Authors
- Jeffrey Yang
- Subhadwip Basu
- Longqin Hu
- Content type: Original Research
- Published: 14 July 2022
- Pages: 1716 - 1739
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Molecular glues: enhanced protein-protein interactions and cell proteome editing
Authors (first, second and last of 4)
- Evita G. Weagel
- Jason M. Foulks
- Steven L. Warner
- Content type: Review Article
- Open Access
- Published: 12 May 2022
- Pages: 1068 - 1087
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Sulfonamide derivatives of cis-imidazolines as potent p53-MDM2/MDMX protein-protein interaction inhibitors
Authors (first, second and last of 8)
- Daniil R. Bazanov
- Nikolay V. Pervushin
- Natalia A. Lozinskaya
- Content type: Original Research
- Published: 08 October 2021
- Pages: 2216 - 2227
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Development of structure-based pharmacophore to target the β-catenin-TCF protein–protein interaction
Authors (first, second and last of 4)
- Piyusha P. Pagare
- Andrew Morris
- Yan Zhang
- Content type: Original Research
- Published: 12 January 2021
- Pages: 429 - 439
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Discovery of sultam-containing small-molecule disruptors of the huntingtin–calmodulin protein–protein interaction
Authors (first, second and last of 7)
- Nicholas J. Klus
- Khushboo Kapadia
- Jeffrey Aubé
- Content type: Original Research
- Published: 12 June 2020
- Pages: 1187 - 1198
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Nrf2 activation through the inhibition of Keap1–Nrf2 protein–protein interaction
Authors
- Sumi Lee
- Longqin Hu
- Content type: Review Article
- Published: 10 April 2020
- Pages: 846 - 867
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Network pharmacology and bioinformatics approach reveals the hypolipidemic mechanism of Dan Tian Jiang Zhi pill
Authors (first, second and last of 5)
- Yanjiao Qi
- Rongxing Zang
- Zhongren Ma
- Content type: Original Research
- Published: 27 November 2019
- Pages: 243 - 254
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Fluorophenols bearing nitrogenated heterocycle moieties, a class of novel Keap1-Nrf2 protein-protein interaction inhibitors: synthesis, antioxidant stress screening and molecular docking
Authors (first, second and last of 5)
- Xiu E Feng
- De Peng Kong
- Qing Shan Li
- Content type: Original Research
- Published: 06 June 2019
- Pages: 1319 - 1337
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The discovery of purine-based agents targeting triple-negative breast cancer and the αB-crystallin/VEGF protein–protein interaction
Authors (first, second and last of 5)
- Nelly A. Fosu-Mensah
- Wen Jiang
- Andrew D. Westwell
- Content type: Original Research
- Open Access
- Published: 21 December 2018
- Pages: 182 - 202
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Combination therapy with p53–MDM2 binding inhibitors for malignancies
Authors (first, second and last of 4)
- Zegao Jin
- Jianfeng Shen
- Chunqi Hu
- Content type: Review Article
- Published: 02 September 2014
- Pages: 1369 - 1379
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Design of lead peptide drugs from mushroom targeting cysteine proteases
Authors (first, second and last of 4)
- Debamitra Chakravorty
- Sumit Singh
- Sanjukta Patra
- Content type: Original Research
- Published: 28 August 2012
- Pages: 2038 - 2049