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Combining the technical push and the business pull for natural flavours

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Biotechnology of Aroma Compounds

Part of the book series: Advances in Biochemical Engineering/Biotechnology ((ABE,volume 55))

Abstract

This paper is an attempt to demonstrate the close interrelationship between the scientific and business aspects of biotechnology and natural flavours, and especially how the market pull and technical push dynamics can be effectively integrated. After all, it is consumers' insistent demand for ‘natural flavours’ and other food ingredients, and also for environmentally friendly products and “green” processes in general, that has greatly stimulated the application of enzymes and microorganisms as catalysts for flavour production. However, this is a highly fragmented and segmented industry; with very many and quite different companies involved, and a very wide range of flavour-conferring molecules, all of which can be permutated or combined creatively so as to meet the requirements of particular product requirements. Hence there are very many diverse and important factors at work which I hope to illustrate in this paper. These include manufacturing, regulatory, patenting, product labelling, raw materials supply and quality, applications and formulation factors that help make this such a challenging and fascinating area to work in. This close interrelationship of scientific and market forces is demonstrated by the following key questions that have to be answered in order for innovation to take place. Can we make the product in good quality and cost-effectively? Is it safe to use? Is there a big enough demand? Can we make and use it exclusively?

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References

  1. Omelianski VL (1923) J Bacteriol 8: 393

    CAS  Google Scholar 

  2. Sell CS (1988) Chem. in Britain Aug 791

    Google Scholar 

  3. Cheetham PSJ (1994) in Applied Biocatalysis (ed Cabral JMS et al.) Harwood Academic Press pp 431

    Google Scholar 

  4. Somogyi LP (1996) Chem and Ind 170

    Google Scholar 

  5. Humphrey A (1993) US Patent 5,185,252

    Google Scholar 

  6. Eaton DC (1994) in Bioprocess Production of Fragrance and Colour Ingredients (ed Gabelman A.) J. Wiley and Sons Inc pp 169 New York, Chichester

    Google Scholar 

  7. Mollet B, Delley M (1990) J Bacteriol 172: 5670

    CAS  Google Scholar 

  8. Germond JE, Lapierre L, Delley M, Mollet B (1995) Mol Gen Genet 248: 407

    Article  CAS  Google Scholar 

  9. Nagodawithana (1994) in Bioprocess production of Fragrance and Colour Ingrediants (ed Gabelman A) J Wiley and Sons Inc pp 135, New York, Chichester

    Google Scholar 

  10. Evenhuis B (1992) Agro-Food Ind High-Tech September/October, 19

    Google Scholar 

  11. Tahara S (1972) Agric Biol Chem 36: 2585

    CAS  Google Scholar 

  12. Takken HJ, Groesbeek NM, Roos, R (1992) in Bioformation of Flavours (Paterson RLS, Charlwood BV, Macleod G and Williams AA eds) pp. 186–200, Royal Society of Chemistry, Cambridge

    Google Scholar 

  13. Farbood MI, Willis BJ (1985) US Patent 4560656

    Google Scholar 

  14. Cheetham PSJ, Maume KA and de Rooij JA (1988) US Patent 5219742

    Google Scholar 

  15. Boog ALGM, van Grinsven AM, Peters ALJ, Roos R, Weig AJ (1990) European Patent Application 0371568.A1

    Google Scholar 

  16. Maume KA, Cheetham PSJ (1991) Biocatalysis 5: 79

    CAS  Google Scholar 

  17. van der Schaft P, Geel I de Jong G, ter Burg N (1994) in Trends in Flavour Research (Maarse H, van der Heij DG eds) Elsevier, Amsterdam 437

    Google Scholar 

  18. Boog ALGM, Peters ALJ, Roos R (1991) European Patent Application 0409321.A1.

    Google Scholar 

  19. Gregory P and Eilerman RG (1989) Patent Convention Application WO8912-134A

    Google Scholar 

  20. Fukuda K (1992) Flav Frag J 20: 35

    CAS  Google Scholar 

  21. Manzoni M, Molinari F, Tirelli A and Aragozzi F (1993) Biotechnol Lett 15: 341

    Article  CAS  Google Scholar 

  22. Page GV, Scire B, Farbood MI (1989) PCT Patent Applic WO89/00 203

    Google Scholar 

  23. Dhavlikar RS and Albroscheit G (1973) Dragoco Rep 20: 251

    Google Scholar 

  24. Cavin JF, Saint C, Divies C (1985) Biotechnol Lett 7: 821

    Article  CAS  Google Scholar 

  25. Kaneuchi CMM, Komagata K (1988) Appl Environ Microbiol 54: 3053

    CAS  Google Scholar 

  26. Cheetham PSJ, Quail MA (1991) US Patent 5007206

    Google Scholar 

  27. Noguchi S, Shimura G, Kimura K, Samejiima H (1976) J Solid-Phase Biochem 1: 105

    CAS  Google Scholar 

  28. Murray WD, Duff SJB (1990) Process Biochm 25: 40

    Google Scholar 

  29. Cooper B (1987) German Patent 3604874

    Google Scholar 

  30. Casey J, Dobb R (1992) Enz Microb Technol 14: 739

    Article  CAS  Google Scholar 

  31. Knuth ME, Sahai OP (1989) Patent Convention Treaty Application WO089/00820

    Google Scholar 

  32. Westcott R, Barraclough J, Cheetham PSJ (1994) Phytochemistry 35: 135

    Article  CAS  Google Scholar 

  33. Hamada T, Sugishita M, Fukushuma Y, Fukase T, Motai H (1991) Process Biochem 26: 39

    Article  CAS  Google Scholar 

  34. Jeffcoat R, Willis BJ (1986) in Developments in Food Science, Proc 10th Int Cong Essential Oils (Lawrence DM, Mookerjee BD, Willis BJ, eds), p. 743–751, Elsevier, London, New York

    Google Scholar 

  35. Uemura N, Taoka A, Takagi M (1988) in Proceedings of the World Conference on Biotechnology for the Fats and Oils Industry (Applewhite TH, ed) pp 148–152 American Oil Chemists' Society

    Google Scholar 

  36. Van Grinsven AM, Peters ALJ, Roos R (1991) European Application 0 443 211 A1

    Google Scholar 

  37. Seitz EW (1994) in Bioprocess Production of Fragrance and Colour Ingredients (ed Gabelman A) J Wiley and Sons Inc pp 95, New York, Chichester

    Google Scholar 

  38. Stump B, Abraham WR, Kieslich K (1982) Ger Pat Applic 3243090

    Google Scholar 

  39. Farbood MI, Morris JA, Seitz EW (1987) US Patent 468307

    Google Scholar 

  40. Farbood MI, Willis BJ, Christenson PA (1989) US Patent 4798799

    Google Scholar 

  41. Hasegawa S, Pelton UA (1983) J Agric Food Chem 31: 178.

    Article  CAS  Google Scholar 

  42. Tada S, Takeuchi T, Sone H, Yamano S, Schofield MA, Hammond, JRM, Inoune T (1995) Proc Eur Brewery Conv Cong Brussels 369

    Google Scholar 

  43. Kielland-Brandt MC, Gjermansen C, Nilsson-Tilgren T, Holmberg S (1989) Proc Eur Brewing Conv Cong Zurich 37

    Google Scholar 

  44. Vila KD, Lee S, Goossens E, Debourg A, Masschelein CA (1995) J Amer Soc Brewing Chemists 53: 49

    Google Scholar 

  45. Miyagawa K, Kanzaku N, Kimura H, Sumino Y, Akiyama S, Nakao (1989) Biotechnology 7: 821

    Article  CAS  Google Scholar 

  46. Yasuyuki M, Yoshinori K, Mitsungi K, Yoshiki Y, Toshio T, Fumio H, Hiroshi N (1989) Jpn Nokai Tokkyo Koho 7p 01, 10,957

    Google Scholar 

  47. Lindsey K, Yeoman MM, Black GM, Mavituna F (1983) FEBS 155: 143

    Article  CAS  Google Scholar 

  48. Lindsey K, Yeoman MM (1980) Proc Eng Aspects Immob Cell Systems (ed Webb C et al.) 1. Chem Eng

    Google Scholar 

  49. Abraham B, Krings U, Berger RG (1993) Chem Mikrobiol Technol Lebensm 15: 178

    CAS  Google Scholar 

  50. Miyazaki JM, Crotean R (1990) Eng Microb Technol 12: 841

    Article  CAS  Google Scholar 

  51. Cheetham PSJ (1991) in Biotechnology—The Science and the Business (Moses V and Cape RE eds) pp. 481–506 Harwood Academic Press, Chur, London, Paris, NY

    Google Scholar 

  52. Cheetham PSJ (1995) in Handbook of Enz. Biotechnol. (ed Wiseman A), Ellis Horwood Academic Publishers, Henel Hampstead, UK, third edition, 83

    Google Scholar 

  53. Drawert F, Barton H (1978) J Agric Food Chem 26: 765

    Article  CAS  Google Scholar 

  54. Cheetham PSJ (1993) TIBTECH 11: 478

    CAS  Google Scholar 

  55. Allen DH (1980) A guide to the economic evaluation of projects. Inst Chem Engs, Rugby, UK

    Google Scholar 

  56. Levitt T (1986) The Marketing Imagination, Collier Macmillan Publishers London

    Google Scholar 

  57. Russell KA (1991) in Biotechnology—The Science and the Business (ed Moses V, Cape RE) Harwood Academic Press pp 9–27

    Google Scholar 

  58. Berger RG (1995) Aroma biotechnology. Springer, Berlin, Heidelberg, New York

    Google Scholar 

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R. G. Berger (Volume Editor)W. Babel H. W. Blanch Ch. L. Cooney S. -O. Enfors K. -E. L. Eriksson A. Fiechter A. M. Klibanov B. Mattiasson S. B. Primrose H. J. Rehm P. L. Rogers H. Sahm K. Schügerl G. T. Tsao K. Venkat J. Villadsen U. von Stockar C. Wandrey

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To my fathers heroes, “the old country people” who lived and worked their lives with nature.

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© 1997 Springer-Verlag

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Cheetham, P.S.J. (1997). Combining the technical push and the business pull for natural flavours. In: Berger, R.G., et al. Biotechnology of Aroma Compounds. Advances in Biochemical Engineering/Biotechnology, vol 55. Springer, Berlin, Heidelberg. https://doi.org/10.1007/BFb0102061

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  • DOI: https://doi.org/10.1007/BFb0102061

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  • Online ISBN: 978-3-540-68602-6

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