Summary
After a single injection, tracer concentration time curves are observed in blood for about 1 minute for determining cardiac output, and for hours or days in obtaining clearance curves. The short term curves resemble skew probability density functions, but the tails cannot be fully observed. By using their inflection triangles such truncated curves are fitted to lognormal, gamma, first passage and local density functions for random walks with drift. These triangles throw light on their geometry, and enable them to be fitted to one another more closely than by equating cumulants.
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© 1975 D. Reidel Publishing Company, Dordrecht-Holland
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Wise, M.E. (1975). Skew Distributions in Biomedicine Including some with Negative Powers of Time. In: Patil, G.P., Kotz, S., Ord, J.K. (eds) A Modern Course on Statistical Distributions in Scientific Work. NATO Advanced Study Institutes Series, vol 17. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-1845-6_18
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DOI: https://doi.org/10.1007/978-94-010-1845-6_18
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