Abstract
A wealth of information is available on disturbances of growth and sexual maturation in patients with thalassaemia major [10, 14–18], but four hormonal data are available on secondary amenorrhoea (SA), which is a common sequela in transfusion-dependent thalassaemic patients, occurring in 15–25% of Italian thalassaemic patients [3, 13]. Similar figures are available for the United Kingdom [8].
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Similar content being viewed by others
References
Backstom LT, McNeilly AS, Leask RM, Baird DT (1982) Pulsatile secretion of LH, FSH, prolactin, oestradiol and progesterone during the human menstrual cycle. Clin Endocrinol (Oxf) 17: 29
Baird, DT (1983) Factors regulating the growth of the pre-ovulatory follicle in the sheep and the human. J Reprod Fertil 69: 343
Borgna-Pignatti C, De Stefano PL, Zonta MS, Vullo C, De Sanctis V, Melevendi C, Naselli A, Masera G, Terzoli S, Gabutti V, Piga A (1985) Growth and sexual maturation in thalassaemia major. J Paediatr 106: 150
Boyar RM, Finkelstein JW, Roffwarg HP, Kapen S, Weitzman E, Hellman L (1972) Synchronization of augmented luteinizing hormone secretion with sleep during puberty. N Engl J Med 287: 582
Boyar RM, Finkelstein JW, Hoffwarg H, Kapen S, Weitzman ED, Hellman L (1973) Twenty-four hour luteinising hormone and follicle-stimulating hormone secretory patterns in gonadal dysgenesis. J Clin Endocrinol Metab 37: 521
Chatterjee R (1992) Ultradian gonadotrophin profiles in patients with beta-thalassaemia major. PhD thesis, University of London
Chatterjee R, Katz M, Wonke B (1989) Secondary amenorrhoea in patients with thalassaemia major (Abstr 346). 3rd World Congress on Fertility and Sterility, Marrakesh
Chatterjee R, Katz M, Wonke B, Porter JB (1992) Long-term follow-up of hypothalamic-pituitary axis in patients with secondary amenorrhoea (Abstr 10). International Mediterranean Conference on Endocrine Disorders in Thalassaemia, May 7-9, Cosenza
Chatterjee R, Katz M, Cox TF, Porter JB (1993) Prospective study of the hypothalamic-pituitary axis in thalassaemic patients who developed secondary amenorrhoea. Clin Endocrinol (Oxf) 39: 287–296
Chatterjee R, Katz M, Cox TF, Bantock HM (1993) Evaluation of growth hormone in thalassaemic boys with failed puberty: spontaneous versus provocative test. Eur J Paediatr 152: 721–726
Costin G, Logut MD, Hyman CB, Ortega JA (1979) Endocrine abnormalities in thalassaemia major. Am J Dis Child 133: 497
De Sanctis V, Vullo C, Katz M, Wonke B, Hoffbrand AV, Bagni B (1988) Hypothalamic-pituitary-gonadal axis in thalassemic patients with secondary amenorrhoea. Obstet Gynecol 72: 643
De Sanctis V, Pintor C, Ando S et al. (1992) Prevalance of endocrine complications in patients with P-thalassaemia major: an Italian multicenter study (Abstr 1). International Mediterranean Conference on Endocrine Disorders in Thalassaemia, May 7-9, Cosenza
Erlandson ME, Brilliant R, Smith CH (1964) Comparison of sixty-six patients with thalassaemia major and thirteen patients with thalassaemia intermedia including growth, development, maturation and prognosis. Ann NY Acad Sci 119: 727
Johnston FE, Hertzog KP, Malina RM (1966) Longitudinal growth in thalassaemia major. Am J Dis Child 122: 396
Kletzky OA, Costin G, Marrs RP, Bernstein G, March CM, Mishell DR Jr (1979) Gonadotropin insufficiency in thalassaemia major. J Clin Endocrinol Metab 48: 901
Kuo B, Zaino E, Roginsky MS (1968) Endocrine function in thalassaemia major. J Clin Endocrinol Metab 28: 805
Lassman MD, O’Brian RT, Pearson HA, Wise JK, Donabedian RK, Felig R, Genel M (1974) Endocrine evaluation in thalassaemia major. Ann NY Acad Sci 232: 226
Marshal JC, Kelch RP (1979) Low-dose pulsatile gonadotrophin-releasing hormone in anorexia nervosa: a model of human pubertal development. J Clin Endocrinol Metab 49: 712
McNatty KP, Gibb M, Dobson C, Thurley DC (1981) Evidence that changes inluteinsing hormone secretion regulate the growth of the pre-ovulatroy follicle in the ewe. J Endocrinol 90: 375
Merriam GR, Watcher KW (1982) Algorithms for the study of episodic hormone secretion. Am J Physiol 243: E310
Miles LE, Lipseitz DA, Bieber CP, Cook JD (1974) Measurement of serum ferritin by a two-site immunradiometric assay. Ann Biochem 61: 209
Peluso JJ, Gruenberg ML, Steger RW (1984) Regulation of ovarian follicular growth and steroidogenesis by low-amplitude LH pulses. Am J Physiol 15: R184
Pohl CR, Knobil E (1982) The role of the central nervous system in the control of ovarian function in higher primates. Annu Rev Physiol 44: 583–593
Reame N, Sauder SE, Case GD, Kelch RP, Marshall JC (1985) Pulsatile gonadotropin secretion in hypothalamic amenorrhoea: evidence that reduced frequency of gonadotrophin-releasing hormone secretion is the mechanism of persistent anovulation. J. Clin Endocrinol Metab 61: 851
Rebar RW, Yen SSW (1979) Endocrine rhythms in gonadotropins and ovarian steroids with reference to reproductive processes. In: Krieger DT (ed) Rebar RW, Yen SSW, p 259 ( Comprehensive endocrinology Series )
Santen RJ, Bardin CW (1973) Episodic luteinising hormone secretion in man: pulse analysis, clinical interpretation, physiologic mechanisms. J Clin Invest 52: 2617
Spratt DI, Carr DB, Merriam GR, Scully RE, Rao N, Crowley WF (1987) the spectrum of abnormal patterns of gonadotrophin-releasing hormone secretion in men with idiopathic hypogonadotrophic hypogonadism: clinical and laboratory correlations. J Clin Endocrinol Metab 64: 283
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1995 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Chatterjee, R., Katz, M., Porter, J.B. (1995). Long-term Follow-up of Hypothalamic-Pituitary Axis in Thalassaemic Patients with Secondary Amenorrhoea. In: Andò, S., Brancati, C. (eds) Endocrine Disorders in Thalassemia. Springer, Milano. https://doi.org/10.1007/978-88-470-2183-9_5
Download citation
DOI: https://doi.org/10.1007/978-88-470-2183-9_5
Publisher Name: Springer, Milano
Print ISBN: 978-88-470-2185-3
Online ISBN: 978-88-470-2183-9
eBook Packages: Springer Book Archive