Thalassemia and Endocrinopathies: Multicenter Study of 3092 Patients

Abstract

Data regarding the prevalence of endocrine dysfunction in patients with β-thalassaemia major are limited [1, 2], We report the results of a collaborative study of endocrine complications in a large series of patients with β-thalassemia major followed in pediatric and hematology departments throughout Italy.

Steering committee: V. De Sanctis, Department of Pediatrics, S. Anna Hospital, Ferrara; C. Pintor, Department of Pediatric Endocrinology, University of Cagliari, Cagliari. Participants: M. Ughi, Department of Pediatrics, S. Anna Hospital, Ferrara; MC. Aliquo, Microcitemia Center, Rome; S. Anastasi, Microcitemia Center, Catania; S. Ando, Department of Cellular Biology, University of Calabria, Cosenza; C. Brancati, Microcitemia Center, Cosenza; M.A. Bruno, Microcitemia Center, Matera; G.A. Cambosu, Department of Pediatrics, Carbonia; A. Castiota Scanderbeg, Department of Pediatrics, University of Parma, Parma; F. Chiavilli, Blood Bank, Rovigo; C. Ciaccio, Microcitemia Center, Sciacca, Agrigento; C. Cianciulli, Microcitemia Center, S. Eugenio Hospital, University of Rome, Rome; M. Cisternino, Department of Pediatrics, University of Pavia, Pavia; G. D’Ascola, Microcitemia Center, Reggio Calabria; F. Di Gregorio, Department of Pediatrics, University of Catania, Catania; L. Esposito, Department of Pediatrics, Hematology Service, University of Naples, Naples; M.C. Galati, Microcitemia Center, A. Pugliese Hospital, Catanzaro; D. Gallisai, Microcitemia Center, Division of Therapy University of Sassari, Sassari; M.R. Gamberini, Department of Pediatrics, S. Anna Hospital, Ferrara; C. Gerardi, Research Fellow, Department of Pediatries, Agrigento; S. Grimaldi, Microcitemia Center, Crotone; B. Lanzone, Microcitemia Center, Legnago; L. Leardini, Department of Pediatrics, Biella; A. Mangiagli, Department of Pediatrics, Microcitemia Center, Siracusa; C. Melevendi, Department of Pediatrics, Galliera Hospital, Genoa; A. Meo, Department of Pediatrics, Microcitemia Service, University of Messina, Messina; W. Monguzzi, Department of Pediatrics, University of Milan, Monza; R. Naldini, Department of Pediatrics, Adria; A.M. Pasquino, Endocrinology Service, University of Rome, Rome; G. Ponzi, Department of Pediatrics, Casarano; G. Quarta, Microcitemia Center, Brindisi; A. Romondia, Department of Pediatrics, Foggia; L. Ruggiero, Department of Pediatrics, Lecce; A. Saviano, Department of Pediatrics, Cardarelli Hospital, Naples; M.F. Scarfia, Microcitemia Center, Caltanisetta; I. Stefano, Microcitemia Center, SS Annunziata Hospital, Taranto; G. Tamborino, Department of Pediatrics, Gallipoli; S. Terzoli, Department of Pediatrics, University of Milan, Milan