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Titanium for Dental Applications (I)

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Titanium in Medicine

Part of the book series: Engineering Materials ((ENG.MAT.))

Abstract

In the 60’s, commercially-pure titanium optical chambers were used to investigate the anatomy and pathophysiology of tissue injury under controlled experimental conditions [1]. These studies indicated the possibility of establishing a firm connection between titanium and bone, if titanium chambers were introduced into bone with minimal trauma. In fact, these chambers could not be removed from the surrounding bone once it had healed. It was believed, prior to these observations, that metals could not become integrated into bone. From this casual observation Professor Brånemark developed a new concept of “osseointegration” which led to oral implants with predicable success and long-term function. The concept of osseointegration stood in contrast to the leading principle of the time, “fibrointegration”, which aimed to encapsulate implants placed in bone with stratified connective tissue. The hypothesis behind the “fibrointegration” concept was that the soft-tissue interface surrounding an oral implant could resemble the highly vascular periodontal ligament of the natural dentition [2] with its shock-absorbing and sensory functions. This was not the case and the less than optimal clinical outcomes of “fibrointegrated” implants forced their abandonment in favor of “osseointegrated” implants. The concept of “osseointegration”, called ankylosis by others [3], revolutionized the practice of clinical dentistry in the 80s as well as other reconstructive disciplines. Oral implant therapy has improved the chewing ability of edentulous and partially dentate patients with all the related psychological implications.

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References

  1. Brånemark PI, Breine U, Johansson B, Roylance PJ, Röckert H,Yoffey JM (1964) Regeneration of bone marrow. Acta Anat 59:1–46

    Article  Google Scholar 

  2. Weiss CM (1987) A comparative analysis of fibro-osteal and osteal integration and other variables that affect long term bone maintenance around dental implants. J Oral Implantol 13:467–487

    CAS  Google Scholar 

  3. Schroeder A, van der Zypen E, Stich H, Sutter F (1981) The reactions of bone, connective tissue, and epithelium to endosteal implants with titanium-sprayed surfaces. J Max-Fac Surg 9:15–25

    Article  CAS  Google Scholar 

  4. Tolman DE (1995) Reconstructive procedures with endosseous implants in grafted bone: A review of the literature. Int J Oral Maxillofac Implants 10:275–294

    CAS  Google Scholar 

  5. Weingart D, Petrin G (1999) Maxillofacial applications of implants in conjunction with bone grafts. In: Lang NP, Karring T, Lindhe J (eds) Proceedings of the 3rd European Workshop on Periodontology. Implant Dentistry. Quintessence Publishing, Berlin, pp 544–556

    Google Scholar 

  6. Buser D, Brägger U, Lang NP, Nyman S (1990) Regeneration and enlargement of jaw bone using guided tissue regeneration. Clin Oral Implants Res 1:22–32

    Article  CAS  Google Scholar 

  7. Hämmerle CHF (1999) Membranes and bone substitutes in guided bone regeneration. In: Lang NP, Karring T, Lindhe J (eds) Proceedings of the 3rd European Workshop on Periodontology . Implant Dentistry. Quintessence Publishing, Berlin, pp 468–499

    Google Scholar 

  8. Simion M (1999) Horizontal and vertical bone volume augmentation of implant sites using guided bone regeneration (GBR). In: Lang NP, Karring T, Lindhe J (eds) Proceedings of the 3rd European Workshop on Periodontology. Implant Dentistry. Quintessence Publishing, Berlin, pp 500–519

    Google Scholar 

  9. Tulasne JF (1992) Osseointegrated fixtures in the pterygoid region. In: Worthington P, Brånemark PI (eds) Advanced Osseointegration Surgery: Applications in the Maxillofacial Region. Quintessence Publishing, Chicago, pp 182–188

    Google Scholar 

  10. Venturelli A (1996) A modified surgical protocol for placing implants in the maxillary tuber-osity: clinical results at 36 months after loading with fixed partial dentures. Int J Oral Maxillo-fac Implants 11:743–749

    CAS  Google Scholar 

  11. Balshi TJ, Wolfinger GJ, Balshi II SF (1999) Analysis of 356 pterygomaxillary implants in edentulous arches for fixed prosthesis anchorage. Int J Oral Maxillofac Implants 14:398–406

    CAS  Google Scholar 

  12. Weischer T, Schettler D, Mohr C (1997) Titanium implants in the zygoma as retaining elements after hemimaxillectomy. Int J Oral Maxillofac Implants 12:211–214

    CAS  Google Scholar 

  13. Higuchi K, Slack JM (1992) The use of titanium fixtures for intraoral anchorage to facilitate orthodontic tooth movement. In: Laney WR, Tolman DE (eds) Tissue Integration in Oral, Orthopedic and Maxillofacial Reconstruction. Proceedings of the Second International Congress on Tissue Integration in the Oral, Orthopedic, and Maxillofacial Reconstruction. Quintessence Publishing, Chicago, pp 303–309

    Google Scholar 

  14. Ödman J, Lekholm U, Jemt T, Thilander B (1994) Osseointegrated implants as orthodontic anchorage in the treatment of partially edentulous adult patients. Eur J Orthod 16: 187–201

    Article  Google Scholar 

  15. Wehrbein H, Merz BR, Diedrich P, Glatzmaier J (1996) The use of palatal implants for orthodontic anchorage. Design and clinical application of the orthosystem. Clin Oral Implants Res 7:410–416

    Article  CAS  Google Scholar 

  16. Sawaki Y, Ohkubo H, Yamamoto H, Ueda M (1996) Mandibular lengthening by intraoral distraction using osseointegrated implants. Int J Oral Maxillofac Implants 11:186–193

    CAS  Google Scholar 

  17. Urbani G, Lombardo G, Santi E, Consolo U (1999) Distraction osteogenesis to achieve mandibular vertical bone regeneration: A case report. Int J Periodont Rest Dent 19:321–331

    CAS  Google Scholar 

  18. Esposito M, Hirsch JM, Lekholm U, Thomsen P (1998) Biological factors contributing to failures of osseointegrated oral implants. (II) Etiopathogenesis. Eur J Oral Sci 106:721–764

    Article  CAS  Google Scholar 

  19. d’Hoedt B, Schulte W (1989) A comparative study of results with various endosseous implant systems. Int J Oral Maxillofac Implants 4:95–105

    Google Scholar 

  20. Salonen MAM, Oikarinen K, Virtanen K, Pernu H (1993) Failures in the osseointegration of endosseous implants. Int J Oral Maxillofac Implants 8:92–97

    CAS  Google Scholar 

  21. Åstrand P, Almfeldt I, Brunell G, Hamp S-E, Hellem S, Karlsson U (1996) Non-submerged implants in the treatment of the edentulous lower jaw. A 2-year longitudinal study. Clin Oral Implants Res 7:337–344

    Article  Google Scholar 

  22. Mericske-Stern R, Zarb GA (1993) Overdentures: An alternative implant methodology for edentulous patients. Int J Prosthodont 6:203–208

    CAS  Google Scholar 

  23. Buser D, Mericske-Stern R, Bernard JP, Behneke A, Behneke N, Hirt HP, Belser UC, Lang NP (1997) Long-term evaluation of non-submerged ITI implants. Part 1: 8-year life table analysis of prospective multi-center study with 2 359 implants. Clin Oral Implants Res 8:161–172

    Article  CAS  Google Scholar 

  24. Truhlar RS, Farish SE, Scheitler LE, Morris HF, Ochi S (1997) Bone quality and implant design-related outcomes through stage II surgical uncovering of spectra-system root form implants. J Oral Maxillofac Surg 55 (Suppl. 5):46–54

    CAS  Google Scholar 

  25. Morris HF, Manz MC, Tarolli JH (1997) Success of multiple endosseous dental implant designs to second-stage surgery across study sites. J Oral Maxillofac Surg 55 (Suppl. 5):76–82

    CAS  Google Scholar 

  26. Malmqvist JP, Sennerby L (1990) Clinical report on the success of 47 consecutively placed Core-Vent implants followed from 3 months to 4 years. Int J Oral Maxillofac Implants 5:53–60

    CAS  Google Scholar 

  27. Esposito M, Hirsch JM, Lekholm U, Thomsen P (1999) Differential diagnosis and treatment strategies for biologic complications and failing oral implants. A review of the literature. Int J Oral Maxillofac Implants 14:473–490

    CAS  Google Scholar 

  28. Melcher GA, Hauke C, Metzdorf A, Perren G, Schlegel U, Ziegler WJ (1996) Infection after intramedullary nailing: An experimental investigation on rabbits. Injury 27 (Suppl. 3):SC23–26

    Google Scholar 

  29. Buser D, Maeglin B (1996) Complications with ITI implants. In: Schroeder A, Sutter F, Buser D, Krekeler G (eds) Oral Implantology. Basics, ITI Hollow Cylinder System. Georg Thieme Verlag, Stuttgart, pp 445–476

    Google Scholar 

  30. Eckert SE, Parein A, Myshin HL, Padilla JL (1997) Validation of dental implant systems through a review of literature supplied by system manufacturers. J Prosthet Dent 77:271–279

    Article  CAS  Google Scholar 

  31. Esposito M, Hirsch JM, Lekholm U, Thomsen P (1998) Biological factors contributing to failures of osseointegrated oral implants. (I) Success criteria and epidemiology. Eur J Oral Sci 106:527–551

    Article  CAS  Google Scholar 

  32. Kasemo B, Lausmaa J (1985) Metal selection and surface characteristics. In: Brånemark PI, Zarb GA, Albrektsson T (eds) Tissue-Integrated Prostheses. Quintessence Publishing, Chicago, pp 99–116

    Google Scholar 

  33. Wennerberg A, Albrektsson T, Andersson B (1993) Design and surface characteristics of 13 commercially available oral implant systems. Int J Oral Maxillofac Implants 8:622–633

    CAS  Google Scholar 

  34. Olefjord I, Hansson S (1993) Surface analysis of four dental implant systems. Int J Oral Maxillofac Implants 8:32–40

    CAS  Google Scholar 

  35. Helsingen AL, Lyberg T (1994) Comparative surface analysis and clinical performance studies of Brånemark implants and related clones. Int J Oral Maxillofac Implants 9:422–430

    Google Scholar 

  36. Mohammadi S, Wictorin L, Ericson LE, Thomsen P (1995) Cast titanium as implant material. J Mater Sci: Mater Med 6:435–444

    Article  CAS  Google Scholar 

  37. Gotfredsen K, Nimb L, Hjörting-Hansen E, Jensen JS, Holmén A (1992) Histomorphometric and removal torque analysis for TiO2-blasted titanium implants. An experimental study on dogs. Clin Oral Implants Res 3:77–84

    Article  CAS  Google Scholar 

  38. De Leonardis D, Garg AK, Pecora GE (1999) Osseointegration of rough acid-etched titanium implants: 5-year follow-up of 100 minimatic implants. Int J Oral Maxillofac Implants 14:384–391

    Google Scholar 

  39. Huré G, Donath K, Lesourd M, Chappard D, Baslé MF (1996) Does titanium surface treatment influence the bone-implant interface? SEM and histomorphometry in a 6-month sheep study. Int J Oral Maxillofac Implants 11:506–511

    Google Scholar 

  40. Buser D, Nydegger T, Oxland T, Cochran DL, Schenk RK, Hirt HP, Snétivy D, Nolte LP (1999) Interface shear strength of titanium implants with a sandblasted and acid-etched surface: A biomechanical study in the maxilla of miniature pigs. J Biomed Mater Res 45:75–83

    Article  CAS  Google Scholar 

  41. Steinemann S (1996) The properties of titanium. In: Schroeder A, Sutter F, Buser D, Krekeler G (eds) Oral Implantology. Basics, ITI Hollow Cylinder System. Georg Thieme Verlag, Stuttgart, pp 37–58

    Google Scholar 

  42. Pilliar RM (1998) Overview of surface variability of metallic endosseous dental implants: textured and porous surface-structured designs. Implant Dent 7:305–314

    Article  CAS  Google Scholar 

  43. Deporter DA, Friedland B, Watson PA, Pilliar RM, Howley TP, Abdulla D, Melcher AH, Smith DC (1987) A clinical and radiographic assessment of a porous-surfaced, titanium alloy dental implant system in dogs. Int J Oral Implantol 4:31–37

    Google Scholar 

  44. Deporter DA, Watson PA, Pilliar RM, Pharoah M, Smith DC, Chipman M, Locker D, Rydall A (1996) A prospective clinical study in humans of an endosseous dental implant partially covered with a powder-sintered porous coating: 3- to 4-year results. Int J Oral Maxillofac Implants 11:87–95

    CAS  Google Scholar 

  45. Quirynen M, van der Mei HC, Bollen CML, Schotte A, Marechal M, Doombusch GI, Naert I, Busscher HJ, van Steenberghe D (1993) An in vivo study of the influence of the surface roughness of implants on the microbiology of supra- and subgingival plaque. J Dent Res 72:1304–1309

    Article  CAS  Google Scholar 

  46. Quirynen M, Bollen CML, Willems G, van Steenberghe D (1994) Comparison of surface characteristics of six commercially pure titanium abutments. Int J Oral Maxillofac Implants 9:71–76

    CAS  Google Scholar 

  47. Friberg B (1996) Sterile operating conditions for the placement of intraoral implants. J Oral Maxillofac Surg 54:1334–1336

    Article  CAS  Google Scholar 

  48. Dent CD, Olson JW, Farish SE, Bellome J, Casino AJ, Morris HF, Ochi S (1997) The influence of preoperative antibiotics on success of endosseous implants up to and including stage II surgery: a study of 2,641 implants. J Oral Maxillofac Surg 55 (Suppl. 5):19–24

    CAS  Google Scholar 

  49. Brunski JB, Moccia AFJ, Pollack SR, Korostoff E, Trachtenberg DI (1979) The influence of functional use of endosseous dental implants on the tissue-implant interface. I. Histological aspects. J Dent Res 58:1953–1969

    Article  CAS  Google Scholar 

  50. Lazzara RJ (1989) Immediate implant placement into extraction sites: Surgical and restorative advantages. Int J Periodont Rest Dent 9:333–343

    Google Scholar 

  51. Fritz ME (1996) Implant therapy II. Ann Periodont 1:796–815

    Article  CAS  Google Scholar 

  52. Rosenquist B, Grenthe B (1996) Immediate placement of implants into extraction sockets: Implant survival. Int J Oral Maxillofac Implants 11:205–209

    CAS  Google Scholar 

  53. Takeshita F, Iyama S, Ayukawa Y, Suetsugu T, Oishi M (1997) Abscess formation around a hydroxyapatite-coated implant placed into the extraction socket with autogenous bone graft. A histological study using light microscopy, image processing, and confocal laser scanning microscopy. J Periodontol 68:299–305

    Article  CAS  Google Scholar 

  54. Becker W, Becker BE, Israelson H, Lucchini JP, Handelsman M, Ammons W, Rosenberg E, Rose L, Tucker LM, Lekholm U (1997) One-step surgical placement of Brånemark implants: a prospective multicenter clinical study. Int J Oral Maxillofac Implants 12:454–462

    CAS  Google Scholar 

  55. Ericsson I, Randow K, Nilner K, Petersson A (1997) Some clinical and radiographical features of submerged and non-submerged titanium implants. A 5-year follow-up study. Clin Oral Implants Res 8:422–426

    Article  CAS  Google Scholar 

  56. Mayfield LJA (1999) Immediate, delayed and late submerged and transmucosal implants. In: Lang NP, Karring T, Lindhe J (eds) Proceedings of the 3rd European Workshop on Periodon-tology . Implant Dentistry. Quintessence Publishing, Berlin, pp 520–534

    Google Scholar 

  57. Adell R, Lekholm U, Brånemark PI (1985) Surgical procedures. In: Brånemark PI, Zarb GA, Albrektsson T (eds) Tissue-Integrated Prostheses. Quintessence Publishing, Chicago, pp 211–232

    Google Scholar 

  58. Chiapasco M, Gatti C, Rossi E, Haefliger W, Markwalder TH (1997) Implant-retained man-dibular overdentures with immediate loading. A retrospective multicenter study on 226 consecutive cases. Clin Oral Implants Res 8:48–57

    Article  CAS  Google Scholar 

  59. Brånemark PI, Engstrand P, Öhrnell LO, Gröndahl K, Nilsson P, Hagberg K, Darle C, Lekholm U (1999) Brånemark Novum: a new treatment concept for rehabilitation of the edentulous mandible. Preliminary results from a prospective clinical follow-up study. Clin Implant Dent Rel Res 1:2–16

    Article  Google Scholar 

  60. Schnitman PA, Wöhrle PS, Rubenstein JE (1990) Immediate fixed interim prostheses supported by two-stage threaded implants: methodology and results. J Oral Implantol 16:96–105

    CAS  Google Scholar 

  61. Tarnow DP, Emtiaz S, Classi A (1997) Immediate loading of threaded implants at stage 1 surgery in edentulous arches: ten consecutive case reports with 1- to 5-year data. Int J Oral Maxillofac Implants 12:319–324

    CAS  Google Scholar 

  62. Randow K, Ericsson I, Nilner K, Petersson A, Glantz PO (1999) Immediate functional loading of Brånemark dental implants. An 18-month clinical follow-up study. Clin Oral Implants Res 10:8–15

    Article  CAS  Google Scholar 

  63. Esposito M, Hirsch JM, Lekholm U, Thomsen P (1997) Failure patterns of four osseointe-grated oral implant systems. J Mater Sci: Mater Med 8:843–847

    Article  CAS  Google Scholar 

  64. Schnitman PA, Shulman LB (1979) Recommendations of the consensus development conference on dental implants. J Am Dent Assoc 98:373–377

    CAS  Google Scholar 

  65. Bergman B (1983) Evaluation of the results of treatment with osseointegrated implants by the Swedish National Board of Health and Welfare. J Prosthet Dent 50:114–115

    Article  CAS  Google Scholar 

  66. Albrektsson T, Zarb G, Worthington P, Eriksson AR (1986) The long-term efficacy of currently used dental implants: A review and proposed criteria of success. Int J Oral Maxillofac Implants 1:11–25

    CAS  Google Scholar 

  67. (1988) NIH consensus conference statement: Dental implants. Int J Oral Maxillofac Implants 3:290–293

    Google Scholar 

  68. Albrektsson T, Isidor F (1994) Consensus report of session IV. In: Lang NP, Karring T (eds) Proceedings of the 1st European Workshop on Periodontology. Quintessence Publishing, London, pp 365–369

    Google Scholar 

  69. Mombelli A (1994) Criteria for success. Monitoring. In: Lang NP, Karring T (eds) Proceedings of the 1st European Workshop on Periodontology. Quintessence Publishing, London, pp 317–325

    Google Scholar 

  70. Proceedings of the 1996 World Workshop in Periodontics (1996) Consensus report. Implant therapy I. Ann Periodont 1:792–795

    Article  Google Scholar 

  71. Roos J, Sennerby L, Lekholm U, Jemt T, Gröndahl K, Albrektsson T (1997) A qualitative and quantitative method for evaluating implant success: a 5-year retrospective analysis of the Brånemark implant. Int J Oral Maxillofac Implants 12:504–514

    CAS  Google Scholar 

  72. Wennström JL, Palmer RM (1999) Consensus report of Session C. In: Lang NP, Karring T, Lindhe J (eds) Proceedings of the 3rd European Workshop on Periodontology. Implant Dentistry. Quintessence Publishing, Berlin, pp 255–259

    Google Scholar 

  73. Johansson P, Strid KG (1994) Assessment of bone quality from cutting resistance during implant surgery. Int J Oral Maxillofac Implants 9:279–288

    Google Scholar 

  74. Friberg B, Sennerby L, Roos J, Lekholm U (1995) Identification of bone quality in conjunction with insertion of titanium implants. A pilot study in jaw autopsy specimens. Clin Oral Implants Res 6:213–219

    Article  CAS  Google Scholar 

  75. Lekholm U, Zarb GA (1985) Patient selection and preparation. In: Brånemark PI, Zarb GA, Albrektsson T (eds) Tissue-Integrated Prostheses. Quintessence Publishing, Chicago, pp. 199–209

    Google Scholar 

  76. Meredith N, Book K, Friberg B, Jemt T, Sennerby L (1997) Resonance frequency measurements of implant stability in vivo. A cross-sectional and longitudinal study of resonance frequency measurements on implants in the edentulous and partially dentate maxilla. Clin Oral Implants Res 8:226–233

    Article  CAS  Google Scholar 

  77. Olivé J, Aparicio C (1990) The periotest method as a measure of osseointegrated oral implant stability. Int J Oral Maxillofac Implants 5:390–400

    Google Scholar 

  78. Chavez H, Ortman LF, DeFranco RL, Medige J (1993) Assessment of oral implant mobility. J Prosthet Dent 70:421–426

    Article  CAS  Google Scholar 

  79. Isidor F (1998) Mobility assessment with the periotest system in relation to histologic findings of oral implants. Int J Oral Maxillofac Implants 13: 377–383

    CAS  Google Scholar 

  80. Sullivan DY, Sherwood RL, Collins TA, Krogh PHJ (1996) The reverse-torque test: A clinical report. Int J Oral Maxillofac Implants 11:179–185

    CAS  Google Scholar 

  81. Strid K-G (1985) Radiographic procedures. In: Brånemark PI, Zarb GA, Albrektsson T (eds) Tissue-Integrated Prostheses. Quintessence Publishing, Chicago, pp 317–327

    Google Scholar 

  82. Strid K-G (1985) Radiographic results. In: Brånemark PI, Zarb GA, Albrektsson T (eds) Tissue-Integrated Prostheses. Quintessence Publishing, Chicago, pp 187–198.

    Google Scholar 

  83. Gröndahl K, Lekholm U (1997) The predictive value of radiographic diagnosis of implant instability. Int J Oral Maxillofac Implants 12:59–64

    Google Scholar 

  84. Isidor F (1997) Histological evaluation of peri-implant bone at implants subjected to occlusal overload or plaque accumulation. Clin Oral Implants Res 8:1–9

    Article  CAS  Google Scholar 

  85. Salvi GE, Bardet P, Lang NP (1999) Clinical parameters in longitudinal implant studies. In: Lang NP, Karring T, Lindhe J (eds) Proceedings of the 3rd European Workshop on Periodon-tology. Implant Dentistry. Quintessence Publishing, Berlin, pp 217–227

    Google Scholar 

  86. Quirynen M, Naert I, van Steenberghe D, Dekeyser C, Callens A (1992) Periodontal aspects of osseointegrated fixtures supporting a partial bridge. An up to 6-years retrospective study. J Clin Periodontol 19:118–126

    Article  CAS  Google Scholar 

  87. Lekholm U, Adell R, Lindhe J, Brånemark PI, Eriksson B, Rockier B, Lindvall AM, Yon-eyama T (1986) Marginal tissue reactions at osseointegrated titanium fixtures. (II) A cross-sectional retrospective study. Int J Oral Maxillofac Surg 15:53–61

    Article  CAS  Google Scholar 

  88. Ericsson I, Lindhe J (1993) Probing depth at implants and teeth. An experimental study in the dog. J Clin Periodontol 20: 623–627

    Article  CAS  Google Scholar 

  89. Quirynen M, van Steenberghe D, Jacobs R, Schotte A, Darius P (1991) The reliability of pocket probing around screw-type implants. Clin Oral Implants Res 2:186–192

    Article  CAS  Google Scholar 

  90. Lang NP, Wetzel AC, Stich H, Caffesse RG (1994) Histologic probe penetration in healthy and inflamed peri-implant tissues. Clin Oral Implants Res 5:191–201

    Article  CAS  Google Scholar 

  91. Pontoriero R, Tonelli MP, Carnevale G, Mombelli A, Nyman SR, Lang NP (1994) Experimentally induced peri-implant mucositis. Clin Oral Implants Res 5:254–259

    Article  CAS  Google Scholar 

  92. Kao RT, Curtis DA, Richards DW, Preble J (1995) Increased interleukin-1ß in the crevicular fluid of diseased implants. Int J Oral Maxillofac Implants 10:696–701

    CAS  Google Scholar 

  93. Panagakos FS, Aboyoussef H, Dondero R, Jandinski JJ (1996) Detection and measurement of inflammatory cytokines in implant crevicular fluid: a pilot study. Int J Oral Maxillofac Implants 11:794–799

    CAS  Google Scholar 

  94. Salcetti JM, Moriarty JD, Cooper LF, Smith FW, Collins JG, Socransky SS, Offenbacher S (1997) The clinical, microbial, and host response characteristics of the failing implant. Int J Oral Maxillofac Implants 12:32–42

    CAS  Google Scholar 

  95. Esposito M (1999) On Biological Failures of Osseointegrated Oral Implants. Ph.D. thesis, Institute of Anatomy and Cell Biology, Göteborg University, Göteborg, Sweden

    Google Scholar 

  96. Isidor F (1996) Loss of osseointegration caused by occlusal load of oral implants. A clinical and radiographic study in monkeys. Clin Oral Implants Res 7:143–152

    Article  CAS  Google Scholar 

  97. Esposito M, Thomsen P, Mölne J, Gretzer C, Ericson LE, Lekholm U (1997) Immunohis-tochemistry of soft tissues surrounding late failures of Brånemark implants. Clin Oral Implants Res 8:352–366

    Article  CAS  Google Scholar 

  98. Esposito M, Thomsen P, Ericson LE, Lekholm U (1999) Histopathologic observations on early oral implant failures. Int J Oral Maxillofac Implants 14:798–810

    CAS  Google Scholar 

  99. Mombelli A, Lang NP (1992) Antimicrobial treatment of peri-implant infections. Clin Oral Implants Res 3:162–168

    Article  CAS  Google Scholar 

  100. Tonetti MS (1996) Peri-implantitis: biological considerations. J Parodontol Implantol Oral 15:269–284

    Google Scholar 

  101. Merritt K, Brown SA (1981) Metal sensitivity reactions to orthopedic implants. Int J Derm 20:89–94

    Article  CAS  Google Scholar 

  102. Peters MS, Schroeter AL, van Hale HM, Broadbent JC (1984) Pacemaker contact sensitivity. Contact Dermatitis 11:214–218

    Article  CAS  Google Scholar 

  103. Holgers K-M, Roupe G, Tjellström A, Bjursten LM (1992) Clinical, immunological and bacteriological evaluation of adverse reactions to skin-penetrating titanium implants in the head and neck region. Contact Dermatitis 27:1–7

    Article  CAS  Google Scholar 

  104. Kasemo B, Lausmaa J (1986) Surface science aspects on inorganic biomaterials. CRC Crit Rev Biocomp 2:335–380

    Google Scholar 

  105. Lausmaa J (1996) Surface spectroscopic characterization of titanium implant materials. J Electron Spectrosc Relat Phenom 81:343–361

    Article  CAS  Google Scholar 

  106. Lausmaa J, Kasemo B, Mattsson H (1990) Surface spectroscopic characterization of clinical titanium implant materials. Appl Surf Sci 44:133–146

    Article  CAS  Google Scholar 

  107. Baier RE, Meyer AE, Natiella JR, Natiella RR, Carter JM (1984) Surface properties determine bioadhesive outcomes: methods and results. J Biomed Mater Res 18:337–355

    Article  CAS  Google Scholar 

  108. Kasemo B, Lausmaa J (1988) Biomaterial and implant surfaces: On the role of cleanliness, contamination, and preparation procedures. J Biomed Mater Res 22:145–158

    Article  CAS  Google Scholar 

  109. Baier RE, Meyer AE (1988) Implant surface preparation. Int J Oral Maxillofac Implants 3:9–20

    CAS  Google Scholar 

  110. Klauber C, Lenz LJ, Henry PJ (1990) Oxide thickness and surface contamination of six endosseous dental implants determined by electron spectroscopy for chemical analysis: A preliminary report. Int J Oral Maxillofac Implants 5:264–271

    CAS  Google Scholar 

  111. Smith DC (1991) Surface characterization of implant materials: biological implications. In: Davies JE (ed) The Bone-Biomaterial Interface. University of Toronto Press, Toronto, pp 3–18

    Google Scholar 

  112. Arys A, Philippart C, Dourov N, He Y, Le QT, Pireaux JJ (1998) Analysis of titanium dental implants after failure of osseointegration: Combined histological, electron microscopy, and X-ray photoelectron spectroscopy approach. J Biomed Mater Res Appl Biomater 43:300–312

    Article  CAS  Google Scholar 

  113. Lausmaa J, Kasemo B, Hansson S (1985) Accelerated oxide growth on titanium implants during autoclaving caused by fluorine contamination. Biomaterials 6:23–27

    Article  CAS  Google Scholar 

  114. Bjursten LM, Gould TRL, Skalak R, Baier RE, Beertsen W, Ducheyne P, Kasemo B, Pilliar RE (1986) Basic science committee. In: van Steenberghe D, Albrektsson T, Brånemark PI, Henry PJ, Holt R, Lidén G (eds) Tissue Integration in Oral and Maxillo-facial Reconstruction. Excerpta Medica, Amsterdam, pp 511–513

    Google Scholar 

  115. Binon PP, Weir DJ, Marshall SJ (1992) Surface analysis of an original Brånemark implant and three related clones. Int J Oral Maxillofac Implants 7:168–175

    CAS  Google Scholar 

  116. Brånemark PI, Breine U, Adell R, Hansson BO, Lindström J, Ohlsson A (1969) Intra-osseous anchorage of dental prostheses. I. Experimental studies. Scand J Plast Reconstr Surg 3:81–100

    Article  Google Scholar 

  117. Ameen AP, Short RD, Johns R, Schwach G (1993) The surface analysis of implant materials. 1. The surface composition of a titanium dental implant material. Clin Oral Implants Res 4:144–150

    Article  CAS  Google Scholar 

  118. Ivanoff C-J, Sennerby L, Lekholm U (1996) Influence of soft tissue contamination on the integration of titanium implants. An experimental study in rabbits. Clin Oral Implants Res 7:128–132

    Article  CAS  Google Scholar 

  119. Esposito M, Lausmaa J, Hirsch JM, Thomsen P (1999) Surface analysis of failed titanium oral implants. J Biomed Mater Res Appl Biomater 48:559–568

    Article  CAS  Google Scholar 

  120. Michel R (1987) Trace metal analysis in biocompatibility testing. CRC Crit Rev Biocomp 3:235–317

    CAS  Google Scholar 

  121. Lugowski S, Smith DC, VanLoon JC (1990) Critical aspects of trace element analysis of tissue samples: a review. Clin Mater 6:91–104

    Article  CAS  Google Scholar 

  122. Michel R, Nolte M, Reich M, Löer F (1991) Systemic effects of implanted prostheses made of cobalt-chromium alloys. Arch Orthop Traumat Surg 110:61–74

    Article  CAS  Google Scholar 

  123. Keller JC, Young FA, Hansel B (1985) Systemic effects of porous Ti dental implants. Dent Mater 1:41–42

    Article  CAS  Google Scholar 

  124. Osborn JF, Willich P, Meenen N (1990) The release of titanium into human bone from a titanium implant coated with plasma-sprayed titanium. In: Heimke G, Soltész U, Lee AJC (eds) Clinical Implant Materials. Advances in Biomaterials. Elsevier, Amsterdam, pp 75–80

    Google Scholar 

  125. Lugowski SJ, Smith DC, McHugh AD, Van Loon JC (1991) Release of metal ions from dental implant materials in vivo: determination of Al, Co, Cr, Mo, Ni, V, and Ti in organ tissue. J Biomed Mater Res 25:1443–1458

    Article  CAS  Google Scholar 

  126. Smith D, Lugowski S, McHugh A, Deporter D, Watson PA, Chipman M (1997) Systemic metal ion levels in dental implant patients. Int J Oral Maxillofac Implants 12:828–834

    CAS  Google Scholar 

  127. Woodman JL, Jacobs JJ, Galante JO, Urban RM (1984) Metal ion release from titanium-based prosthetic segmental replacements of long bones in baboons: a long-term study. J Orthop Res 1:421–430

    Article  CAS  Google Scholar 

  128. Ducheyne P, Willems G, Martens M, Helsen J (1984) In vivo metal-ion release from porous titanium-fiber material. J Biomed Mater Res 18:293–308

    Article  CAS  Google Scholar 

  129. Revell PA, Al-Saffar N, Kobayashi A (1997) Biological reaction to debris in relation to joint prostheses. Proc Instn Mech Engrs 211:187–196

    Article  CAS  Google Scholar 

  130. Haynes DR, Rogers SD, Hay S, Pearcy MJ, Howie DW (1993) The differences in toxicity and release of bone-resorbing mediators induced by titanium and cobalt-chromium-alloy wear particles. J Bone Joint Surg 75-A:825–834

    Google Scholar 

  131. Maloney WJ, Smith RL (1995) Periprosthetic osteolysis in total hip arthroplasty: the role of particulate wear debris. J Bone Joint Surg 77-A:1448–1461

    Google Scholar 

  132. Katou F, Andoh N, Metegi K, Nagura H (1996) Immuno-inflammatory responses in the tissue adjacent to titanium miniplates used in the treatment of mandibular fractures. J Cranio-maxillofac Surg 24:155–162

    Article  CAS  Google Scholar 

  133. Barth E, Sullivan T (1992) Complement fixation by polymethyl methacrylate and titanium, and the impact on macrophage migration. In: Laney WR, Tolman DE (eds) Tissue Integration in Oral, Orthopedic and Maxillofacial Reconstruction. Proceedings of the Second International Congress on Tissue Integration in the Oral, Orthopedic and Maxillofacial Reconstruction. Quintessence Publishing, Chicago, pp 33–36

    Google Scholar 

  134. Perala D, Chapman R, Gelfand J (1991) Complement activation by dental implants. Int J Oral Maxillofac Implants 6:136–141

    CAS  Google Scholar 

  135. Weingart D, Steinemann S, Schilli W, Strub JR, Hellerich U, Assenmacher J, Simpson J (1994) Titanium deposition in regional lymph nodes after insertion of titanium screw implants in maxillofacial region. Int J Oral Maxillofac Surg 23:450–452

    Article  CAS  Google Scholar 

  136. Schliephake H, Reiss G, Urban R, Neukam FW, Guckel S (1993) Metal release from titanium fixtures during placement in the mandible: An experimental study. Int J Oral Maxillofac Implants 8:502–511

    CAS  Google Scholar 

  137. Rae T (1986) The biological response to titanium and titanium-aluminium-vanadium alloy particles. II. Long-term animal studies. Biomaterials 7:37–40

    Article  CAS  Google Scholar 

  138. Howie DW, Vernon-Roberts B (1988) Long-term effects of intraarticular cobalt-chrome alloy wear particles in rats. J Arthroplasty 3:327–336

    Article  CAS  Google Scholar 

  139. Goodman SB (1994) The effects of micromotion and particulate materials on tissue differentiation. Bone chamber studies in rabbits. Acta Orthop Scand 65 (Suppl. 258):l–43

    Google Scholar 

  140. Lüthy H, Strub JR, Schärer P (1987) Analysis of plasma flame-sprayed coatings on endos-seous oral titanium implants exfoliated in man: preliminary results. Int J Oral Maxillofac Implants 2:197–202

    Google Scholar 

  141. Lüthy H, Strub JR (1988) Thickness of plasma flame-sprayed coatings on titanium implants exfoliated in dogs. Int J Oral Maxillofac Implants 3:269–273

    Google Scholar 

  142. Kuliralo M, Pireaux JJ, Caudano R, Dourov N (1991) Surface studies on titanium IMZ implants. J Biol Buccale 19:247–253

    CAS  Google Scholar 

  143. Steinemann SG (1998) Titanium - the material of choice? Periodontol 2000 17:7–21

    Article  CAS  Google Scholar 

  144. Morgan MJ, James DF, Pilliar R (1993) Fractures of the fixture component of an osseointe-grated implant. Int J Oral Maxillofac Implants 8:409–414

    CAS  Google Scholar 

  145. Balshi TJ (1996) An analysis and management of fractured implants: A clinical report. Int J Oral Maxillofac Implants 11:660–666

    CAS  Google Scholar 

  146. Rangert B, Krogh PHJ, Langer B, Van Roekel N (1995) Bending overload and implant fracture: A retrospective clinical analysis. Int J Oral Maxillofac Implants 10:326–334

    CAS  Google Scholar 

  147. Wang RR, Fenton A (1996) Titanium for prosthodontic applications: a review of the literature. Quintessence Int 27:401–408

    CAS  Google Scholar 

  148. Lide DR (1999) CRC Handbook of Chemistry and Physics. CRC Press, Boca Raton.

    Google Scholar 

  149. Miyakawa O, Watanabe K, Okawa S, Nakano S, Kobayashi M, Shiokawa N (1989) Layered structure of cast titanium surface. Dent Mater J 8:175–185

    Article  CAS  Google Scholar 

  150. Wictorin L, El-Mahallawy N, Taha MA, Fredriksson H (1992) Metallographic studies of cast titanium - an experimental study of metal/mould reaction. Cast Metals 4:182–187

    Google Scholar 

  151. Hamanaka H, Doi H, Yoneyama T, Okuno O (1989) Dental casting of titanium and Ni-Ti alloys by a new casting machine. J Dent Res 68:1529–1533

    Article  CAS  Google Scholar 

  152. Bessing C, Bergman M (1992) The castability of unalloyed titanium in three different casting machines. Swed Dent J 16:109–113

    CAS  Google Scholar 

  153. Bridgeman JT, Marker VA, Hummel SK, Benson BW, Pace LL (1997) Comparison of titanium and cobalt-chromium removable partial denture clasps. J Prosthet Dent 78:187–193

    Article  CAS  Google Scholar 

  154. Mori T, Togaya T, Jean-Louis M, Yabugami M (1997) Titanium for removable dentures. I. Laboratory procedures. J Oral Rehabil 24:338–341

    Article  CAS  Google Scholar 

  155. Kimura H, Horng CJ, Okazaki M, Takahashi J (1990) Oxidation effects on porcelain-titanium interface reactions and bond strength. Dent Mater J 9:91–99

    Article  CAS  Google Scholar 

  156. Blackman R, Barghi N, Tran C (1991) Dimensional changes in casting titanium removable partial denture frameworks. J Prosthet Dent 65:309–315

    Article  CAS  Google Scholar 

  157. Togaya T, Suzuki M, Tsutsumi S, Ida K (1983) An application of pure titanium to the metal porcelain system. Dent Mater J 2:210–219

    Article  CAS  Google Scholar 

  158. Adachi M, Mackert JRJ, Parry EE, Fairhurst CW (1990) Oxide adherence and porcelain bonding to titanium and Ti-6A14V alloy. J Dent Res 69:1230–1235

    Article  CAS  Google Scholar 

  159. Boening KW, Walter MH, Reppel PD (1992) Non-cast titanium restorations in fixed prosth-odontics. J Oral Rehabil 19:281–287

    Article  CAS  Google Scholar 

  160. Walter M, Boning K, Reppel P-D (1994) Clinical performance of machined titanium restorations. J Dent 22:346–368

    Article  CAS  Google Scholar 

  161. Pang IC, Gilbert JL, Chai J, Lautenschlager EP (1995) Bonding characteriastics of low-fusing porcelain bonded to pure titanium and palladium-copper alloy. J Prosthet Dent 73:17–25

    Article  CAS  Google Scholar 

  162. Chai J, McGivney GP, Munoz CA, Rubenstein JE (1997) A multicenter longitudinal clinical trial of a new system for restorations. J Prosthet Dent 77:1–11

    Article  CAS  Google Scholar 

  163. Kaus T, Pröbster L, Weber H (1996) Clinical follow-up study of ceramic veneered titanium restorations - Three-year results. Int J Prosthodont 9:9–15

    CAS  Google Scholar 

  164. Jemt T, Lindén B (1992) Fixed implant-supported prostheses with welded titanium frameworks. Int J Periodont Rest Dent 12:177–183

    CAS  Google Scholar 

  165. Berg E (1997) Dentists’ opinions on aspects of cast titanium restorations. J Dent 25:113–117

    Article  CAS  Google Scholar 

  166. Sjögren G, Andersson M, Bergman M (1988) Laser welding of titanium in dentistry. Acta Odontol Scand 46:247–253

    Article  Google Scholar 

  167. Bergendal B, Palmqvist S (1999) Laser-welded titanium frameworks for implant-supported fixed prostheses: a 5-year report. Int J Oral Maxillofac Implants 14:69–71

    CAS  Google Scholar 

  168. Örtorp A, Linden B, Jemt T (1999) Clinical experiences with laser-welded titanium frameworks supported by implants in the edentulous mandible: a 5-year follow-up study. Int J Prosthodont 12:65–72

    Google Scholar 

  169. Jemt T, Bergendal B, Arvidsson K, Bergendal T, Karlsson U, Linden B, Palmqvist S, Rund-crantz T, Bergström C (1998) Laser-welded titanium frameworks supported by implants in the edentulous maxilla: a 2-year prospective multicenter study. Int J Prosthodont 11:551–557

    CAS  Google Scholar 

  170. Riedy SJ, Lang BR, Lang BE (1997) Fit of implant frameworks fabricated by different techniques. J Prosthet Dent 78:596–604

    Article  CAS  Google Scholar 

  171. Jemt T (1995) Three-dimensional distortion of gold alloy castings and welded titanium frameworks. Measurements of the precision of fit between completed implant prostheses and the master casts in routine edentulous situations. J Oral Rehabil 22:557–564

    Article  CAS  Google Scholar 

  172. Andersson M (1996) Procera, a New System for Fabrication of Artificial Dental Crowns. Process-Related and Clinical Studies. Ph.D. thesis, Department of Prosthetic Dentistry, Umeå University, Umeå, Sweden

    Google Scholar 

  173. Andersson M, Carlsson L, Persson M, Bergman B (1996) Accuracy of machine milling and spark erosion with a CAD/CAM system. J Prosthet Dent 76:187–193

    Article  CAS  Google Scholar 

  174. Leong D, Chai J, Lautenschlager E, Gilbert J (1994) Marginal fit of machine-milled titanium and cast titanium single crowns. Int J Prosthodont 7:440–447

    CAS  Google Scholar 

  175. Lövgren R, Andersson B, Bergovist S, Carlsson GE, Ekström PF, Ödman P, Sundqvist B (1997) Clinical evaluation of ceramic veneered titanium restorations according to the Procera technique. Swed Dent J 21:1–10

    Google Scholar 

  176. Smedberg JI, Ekenbäck J, Lothigius E, Arvidson K (1998) Two-year follow-up study of Procera-ceramic fixed partial dentures. Int J Prosthodont 11:145–149

    CAS  Google Scholar 

  177. Milleding P, Haag P, Neroth B, Renz I (1998) Two years of clinical experience with Procera titanium crowns. Int J Prosthodont 11:224–232

    CAS  Google Scholar 

  178. Bergman B, Nilson H, Andersson M (1999) A longitudinal clinical study of Procera ceramic-veneered titanium copings. Int J Prosthodont 12:135–139

    CAS  Google Scholar 

  179. Bergman B, Bessing C, Ericson G, Lundquist P, Nilson H, Andersson M (1990) A 2-year follow-up study of titanium crowns. Acta Odontol Scand 48:113–117

    Article  CAS  Google Scholar 

  180. Ida K, Tani Y, Tsutsumi S, Togaya T, Nambu T, Suese K, Kawazoe T, Nakamura M, Wada H (1985) Clinical application of pure titanium crowns. Dent Mater J 4:191–195

    Article  CAS  Google Scholar 

  181. Yamauchi M, Sakai M, Kawano J (1988) Clinical application of pure titanium for cast plate dentures. Dent Mater J 7:39–47

    Article  CAS  Google Scholar 

  182. Wang RR, Boyle AM (1993) A simple method for inspection of porosity in titanium castings. J Prosthet Dent 70:275–276

    Article  CAS  Google Scholar 

  183. Latta GHJ, McDougal S, Bowles III WF (1993) Response of known nickel-sensitive patient to a removable partial denture with a titanium alloy framework: a clinical report. J Prosthet Dent 70:109–110

    Article  Google Scholar 

  184. Könönen M, Rintanen J, Waltimo A, Kempainen P (1995) Titanium framework removable partial denture used for patient allergic to other metals: a clinical report and literature review. J Prosthet Dent 73:4–7

    Article  Google Scholar 

  185. Thomas CJ, Lechner S, Mori T (1997) Titanium for removable dentures. II. Two-year clinical observations. J Oral Rehabil 24:414–4l8

    Article  CAS  Google Scholar 

  186. Wakabayashi N, Ai M (1997) A short-term clinical follow-up study of superplastic titanium alloy for major connectors of removable partial dentures. J Prosthet Dent 77:583–537

    Article  CAS  Google Scholar 

  187. Campbell JB, Bassett CAL (1956) The surgical application of monomolecular filters (milli-pore) to bridge gaps in peripheral nerves and to prevent neuroma formation. Surg Forum 7:570–574

    Google Scholar 

  188. Dahlin C (1994) Scientific background of guided bone regeneration. In: Buser D, Dahlin C, Schenk RK (eds) Guided Bone Regeneration in Implant Dentistry, Quintessence Publishing, Chicago, pp 31–48

    Google Scholar 

  189. Simion M, Trisi P, Piattelli A (1994) Vertical ridge augmentation using a membrane technique associated with osseointegrated implants. Int J Periodont Rest Dent 14:497–511

    Google Scholar 

  190. Jovanovic SA, Schenk RK, Orsini M, Kenney EB (1995) Supracrestal bone formation around dental implants: an experimental dog study. Int J Oral Maxillofac Implants 10:23–31

    CAS  Google Scholar 

  191. Jovanovic SA, Nevins M (1995) Bone formation utilizing titanium-reinforced barrier membranes. Int J Periodont Rest Dent 15:57–69

    Google Scholar 

  192. Tinti C, Parma-Benfenati S, Polizzi G (1996) Vertical ridge augmentation: what is the limit? Int J Periodont Rest Dent 16:221–229

    Google Scholar 

  193. Tinti C, Parma-Benfenati S (1998) Vertical ridge augmentation: surgical protocol and retrospective evaluation of 48 consecutively inserted implants. Int J Periodont Rest Dent 18:435–443

    Google Scholar 

  194. Simion M, Jovanovic SA, Trisi P, Scarano A, Piattelli A (1998) Vertical ridge augmentation around dental implants using a membrane technique and autogenous bone or allografts in humans. Int J Periodont Rest Dent 18:8–23

    CAS  Google Scholar 

  195. Simion M, Dahlin C, Blair K, Schenk RK (1999) Effect of different microstructures of e-PTFE membranes on bone regeneration and soft tissue response: a histologic study in canine mandible. Clin Oral Implants Res 10:73–84

    Article  CAS  Google Scholar 

  196. von Arx T, Hardt N, Wallkamm B (1996) The TIME technique: a new method for localized alveolar ridge augmentation prior to placement of dental implants. Int J Oral Maxillofac Implants 11:387–394

    Google Scholar 

  197. von Arx T, Wallkamm B, Hardt N (1998) Localized ridge augmentation using a micro titanium mesh: a report on 27 implants followed from 1 to 3 years after functional loading. Clin Oral Implants Res 9:123–130

    Article  Google Scholar 

  198. von Arx T, Kurt B (1998) Implant placement and simultaneous peri-implant bone grafting using a micro titanium mesh for graft stabilization. Int J Periodont Rest Dent 18:117–127

    Google Scholar 

  199. Malchiodi L, Scarano A, Quaranta M, Piattelli A (1998) Rigid fixation by means of titanium mesh in edentulous ridge expansion for horizontal ridge augmentation in the maxilla. Int J Oral Maxillofac Implants 13:701–705

    CAS  Google Scholar 

  200. Leghissa GC, Zaffe D, Assenza B, Botticelli AR (1999) Guided bone regeneration using titanium grids: report of 10 cases. Clin Oral Implants Res 10:62–68

    Article  CAS  Google Scholar 

  201. von Arx T, Kurt B (1999) Implant placement and simultaneous ridge augmentation using autogenous bone and a micro titanium mesh: a prospective clinical study with 20 implants. Clin Oral Implants Res 10:24–33

    Article  Google Scholar 

  202. Celletti R, Davarpanah M, Etienne D, Pecora G, Tecucianu J-F, Donath K (1994) Guided tissue regeneration around dental implants in immediate extraction sockets: comparison of e-PTFE and a new titanium membrane. Int J Periodont Rest Dent 14:243–253

    Google Scholar 

  203. Schliephake H, Lehmann H, Kunz U, Schmelzeisen R (1993) Ultrastructural findings in soft tissues adjacent to titanium plates used in jaw fracture treatment. Int J Oral Maxillofac Surg 22:20–25

    Article  CAS  Google Scholar 

  204. Torgersen S, Gjerdet NR, Erichsen ES, Bang G (1995) Metal particles and tissue changes adjacent to miniplates. A retrieval study. Acta Odontol Scand 53:65–71

    Article  CAS  Google Scholar 

  205. Torgersen S, Moe G, Jonsson R (1995) Immunocompetent cells adjacent to stainless steel and titanium maniplates and screws. Eur J Oral Sci 103:46–54

    Article  CAS  Google Scholar 

  206. Waters NE (1992) Superelastic nickel-titanium wires. Br J Orthod 19:319–322

    CAS  Google Scholar 

  207. Cobb III NW, Kula KS, Phillips C, Proffit WR (1998) Efficiency of multi-strand steel, super-elastic Ni-Ti and ion-implanted Ni-Ti archwires for initial alignment. Clin Orthod Res 1:12–19

    Google Scholar 

  208. Rudner EJ, Clendenning WE, Epstein E, Fisher AA, Jillson OF, Jordan WP, Kanof N, Larsen W, Maibach H, Mitchell JC, O’Quinn SE, Schorr WF, Sulzberger MB (1973) Epidemiology of contact dermatitis in North America: 1972. Arch Dermatol 108:537–540

    Article  Google Scholar 

  209. Rudner EJ, Clendenning WE, Epstein E, Fisher AA, Jillson OF, Jordan WP, Kanof N, Larsen W, Maibach H, Mitchell JC, O’Quinn SE, Schorr WF, Sulzberger MB (1975) The frequency of contact sensitivity in North America 197274. Contact Dermatitis 1:277–280

    Article  Google Scholar 

  210. Bass JK, Fine H, Cisneros GJ (1993) Nickel hypersensitivity in the orthodontic patient. Am J Orthod Dentofac Orthop 103:280–285

    Article  CAS  Google Scholar 

  211. Kim H, Johnson JW (1999) Corrosion of stainless steel, nickel-titanium, coated nickel-titanium, and titanium orthodontic wires. Angle Orthod 69:39–44

    CAS  Google Scholar 

  212. Jones TK, Hansen CA, Singer MT, Kessler HP (1986) Dental implications of nickel hypersensitivity. J Prosthet Dent 56:507–509

    Article  CAS  Google Scholar 

  213. Hamula DW, Hamula W, Sernetz F (1996) Pure titanium orthodontic brackets. J Clin Orthod 30:140–144

    CAS  Google Scholar 

  214. Pettiette MT, Metzger Z, Phillips C, Trope M (1999) Endodontic complications of root canal therapy performed by dental students with stainless-steel K-files and nickel-titanium hand files. J Endodon 25:230–234

    Article  CAS  Google Scholar 

  215. Berry KA, Loushine RJ, Primack PD, Runyan DA (1998) Nickel-titanium versus stainless-steel finger spreaders in curved canals. J Endodon 24:752–754

    Article  CAS  Google Scholar 

  216. Schäfer E (1997) Root canal instruments for manual use: a review. Endod Dent Traumatol 13:51–64

    Article  Google Scholar 

  217. Tepel J, Schäfer E (1997) Endodontic hand instruments: cutting efficiency, instrumentation of curved canals, bending and torsional properties. Endod Dent Traumatol 13:201–210

    Article  CAS  Google Scholar 

  218. Weine FS, Frank AL (1993) Survival of the endodontic endosseous implant. J Endodon 19:524–528

    Article  CAS  Google Scholar 

  219. Larsen RM, Patten JR, Wayman BE (1989) Endodontic endosseous implants: Case reports and update of material. J Endodon 15:496–500

    Article  CAS  Google Scholar 

  220. Messing JJ (1980) The use of titanium cones and apical tips as root filling materials. A clinical evaluation. Br Dent J 148:41–44

    Article  CAS  Google Scholar 

  221. Goss JM, Wright WJJ, Bowles III WF (1992) Radiographic appearance of titanium alloy prefabricated posts cemented with different luting materials. J Prosthet Dent 67:632–637

    Article  CAS  Google Scholar 

  222. Kleier DJ, Shibilski K, Averbach RE (1999) Radiographic appearance of titanium posts in endodontically treated teeth. J Endodon 25:128–131

    Article  CAS  Google Scholar 

  223. Sundgren J-E, Bodö P, Lundström I (1986) Auger electron spectroscopic studies of the interface between human tissue and implants of titanium and stainless steel. J Colloid Interface Sci 10:9–20

    Article  Google Scholar 

  224. Eliades T (1997) Passive film growth on titanium alloys: physicochemical and biologic considerations. Int J Oral Maxillofac Implants 12:621–627

    CAS  Google Scholar 

  225. Gabriel BL, Gold J, Gristina AG, Kasemo B, Lausmaa J, Harrer C, Myrvik QN (1994) Site-specific adhesion of Staphylococcus epidermidis (RP12) in Ti-Al-V metal systems. Biomaterials 15:628–634

    Article  CAS  Google Scholar 

  226. Chang CC, Merritt K (1994) Infection at the site of implanted materials with and without preadhered bacteria. J Orthop Res 12:526–531

    Article  CAS  Google Scholar 

  227. Cordero J, Munuera L, Folgueira MD (1994) Influence of metal implants on infection. An experimental study in rabbits. J Bone Joint Surg 76-B:717–720

    Google Scholar 

  228. Arens S, Schlegel U, Printzen G, Ziegler W, Perren H (1996) Influence of materials for fixation implants on local infection. An experimental study of steel versus titanium DCP in rabbits. J Bone Joint Surg 78-B:647–651

    Google Scholar 

  229. Søballe K, Hansen ES, Brockstedt-Rasmussen H, Pedersen CM, Bünger C (1990) Hydroxyapatite coating enhances fixation of porous coated implants. A comparison in dogs between press fit and noninterference fit. Acta Orthop Scand 61:299–306

    Article  Google Scholar 

  230. Søballe K, Hansen ES, Brockstedt-Rasmussen H, Hjortdal VE, Juhl GI, Pedersen CM, Hvid I, Bünger C (1991) Gap healing enhanced by hydroxyapatite coating in dogs. Clin Orthop 272:300–307

    Google Scholar 

  231. Søballe K, Hansen ES, Brockstedt-Rasmussen H, Bünger C (1993) Hydroxyapatite coating converts fibrous tissue to bone loaded implants. J Bone Joint Surg 75-B:270–278

    Google Scholar 

  232. Geesink RG, de Groot K, Klein CP (1987) Chemical implant fixation using hydroxyl-apatite coatings. The development of a human total hip prosthesis for chemical fixation to bone using hydroxyl-apatite coatings on titanium substrates. Clin Orthop 147–170

    Google Scholar 

  233. Weyant RJ, Burt BA (1993) An assessment of survival rates and within-patient clustering of failures for endosseous oral implants. J Dent Res 72:2–8

    Article  CAS  Google Scholar 

  234. Wheeler S (1996) Eight-year clinical retrospective study of titanium plasma-sprayed and hydroxyapatite-coated cylinder implants. Int J Oral Maxillofac Implants 11:340–350

    CAS  Google Scholar 

  235. Weinlaender M, Beumer III J, Kenney EB, Moy PK (1992) Raman microprobe investigation of the calcium phosphate phases of three commercially available plasma-flame sprayed hydroxyapatite-coated dental implants. J Mater Sci: Mater Med 3:397–401

    Article  CAS  Google Scholar 

  236. Ducheyne P, Beight J, Cuckler J, Evans B, Radin S (1990) Effect of calcium phosphate coating characteristics on early post-operative bone tissue ingrowth. Biomaterials 11:531–540

    Article  CAS  Google Scholar 

  237. Müller-Mai CM, Voigt C, Gross U (1990) Incorporation and degradation of hydroxyapatite implants of different surface roughness and surface structure in bone. Scanning Microsc 4:613–624

    Google Scholar 

  238. Ellingsen JE (1995) Pre-treatment of titanium implants with fluoride improves their retention in bone. J Mater Sci: Mater Med 6:749–753

    Article  CAS  Google Scholar 

  239. Bessho K, Carnes DL, Cavin R, Chen H-Y, Ong JL (1999) BMP stimulation of bone response adjacent to titanium implants in vivo. Clin Oral Implants Res 10:212–218

    Article  CAS  Google Scholar 

  240. Xiang W, Baolin L, Yan J, Yang X (1993) The effect of bone morphogenetic protein on osseointegration of titanium implants. J Oral Maxillofac Surg 51:647–651

    Article  CAS  Google Scholar 

  241. Lynch SE, Buser D, Hernandez RA, Weber HP, Stich H, Fox CH, Williams RC (1991) Effects of the platelet-derived growth factor/insulin-like growth factor-I combination on bone regeneration around titanium dental implants. Results of a pilot study in beagle dogs. J Periodontol 62:710–716

    Article  CAS  Google Scholar 

  242. Jemt T (1994) Fixed implant-supported prostheses in the edentulous maxilla. A five-year follow-up report. Clin Oral Implants Res 5:142–147

    Article  CAS  Google Scholar 

  243. Henry PJ, Bower RC, Wall CD (1995) Rehabilitation of the edentulous mandible with osseointegrated dental implants: 10 year follow-up. Aust Dent J 40:1–9

    Article  CAS  Google Scholar 

  244. Lindquist LW, Carlsson GE, Jemt T (1996) A prospective 15-year follow-up study of man-dibular fixed prostheses supported by osseointegrated implants. Clinical results and marginal bone loss. Clin Oral Implants Res 7:329–336

    Article  CAS  Google Scholar 

  245. Zarb GA, Schmitt A (1996) The edentulous predicament I: a prospective study of the effectiveness of implant-supported fixed prostheses. J Am Dent Assoc 127:59–65

    CAS  Google Scholar 

  246. Friberg B, Nilson H, Olsson M, Palmquist C (1997) Mk II: the self-tapping Brånemark implant: 5-year results of a prospective 3-center study. Clin Oral Implants Res 8:279–285

    Article  CAS  Google Scholar 

  247. Jemt T, Lekholm U (1995) Implant treatment in edentulous maxillae: A 5-year follow-up report on patients with different degrees of jaw resorption. Int J Oral Maxillofac Implants 10:303–311

    CAS  Google Scholar 

  248. Jemt T, Chai J, Harnett J, Heath MR, Hutton JE, Johns RB, McKenna S, McNamara DC, van Steenberghe D, Taylor R, Watson RM, Herrmann I (1996) A 5-year prospective multicenter follow-up report on overdentures supported by osseointegrated implants. Int J Oral Maxillo-fac Implants 11:291–298

    CAS  Google Scholar 

  249. Naert I, Gizani S, Vuylsteke M, van Steenberghe D (1998) A 5-year randomized clinical trial on the influence of splinted and unsplinted oral implants in the mandibular overdenture therapy. Part I: Peri-implant outcome. Clin Oral Implants Res 9:170–177

    Article  CAS  Google Scholar 

  250. Jemt T, Lekholm U (1993) Oral implant treatment in posterior partially edentulous jaws: A 5-year follow-up report. Int J Oral Maxillofac Implants 8:635–640

    CAS  Google Scholar 

  251. Lekholm U, van Steenberghe D, Herrmann I, Bolender C, Folmer T, Gunne J, Henry P, Higuchi K, Laney WR, Lindén U (1994) Osseointegrated implants in the treatment of partially edentulous jaws: A prospective 5-year multicenter study. Int J Oral Maxillofac Implants 9:627–635

    Google Scholar 

  252. Gunne J, Åstrand P, Lindh T, Borg K, Olsson M (1999) Tooth-implant and implant supported fixed partial dentures: a 10-year report. Int. J. Prostodont 12:216–221

    CAS  Google Scholar 

  253. Wennerberg A, Jemt T (1999) Complications in partially edentulous implant patients: a 5-year retrospective follow-up study of 133 patients supplied with unilateral maxillary prostheses. Clin Implant Dent Rel Res 1:49–56

    Article  CAS  Google Scholar 

  254. Henry PJ, Laney WR, Jemt T, Harris D, Krogh PHJ, Polizzi G, Zarb GA, Herrmann I (1996) Osseointegrated implants for single-tooth replacement: A prospective 5-year multicenter study. Int J Oral Maxillofac Implants 11:450–455

    CAS  Google Scholar 

  255. Andersson B, Ödman P, Lindvall AM, Brånemark PI (1998) Cemented single crowns on osseointegrated implants after 5 years: results from a prospective study on CeraOne. Int J Prosthodont 11:212–218

    CAS  Google Scholar 

  256. Andersson B, Ödman P, Lindvall AM, Brånemark PI (1998) Five-year prospective study of prosthodontic and surgical single-tooth implant treatment in general practices and at a specialist clinic. Int J Prosthodont 11:351–355

    CAS  Google Scholar 

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  1. Institute of Anatomy & Cell Biology, Göteborg University, Göteborg, Sweden

    Marco Esposito

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© 2001 Springer-Verlag Berlin Heidelberg

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Esposito, M. (2001). Titanium for Dental Applications (I). In: Titanium in Medicine. Engineering Materials. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-56486-4_24

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  • DOI: https://doi.org/10.1007/978-3-642-56486-4_24

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-63119-1

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