Abstract
A new cardiac contractility index derived from pump flow (IQ) has been developed for rotary blood pumps (RBPs) recipients, to determine preservation and eventual recovery of the remaining cardiac function. Pulse flow indices were used for comparison with IQ during pump speed changes.
Pump flow was recorded in animal experiments and clinically in RBP recipients (MicroMed DeBakey LVAD®) at different pump speeds. IQ was derived from the maximal derivative of pump flow versus QP2P relationship (dQ/dtmax vs. QP2P) during speed variations. IQ was compared to classical indices. Further, simple currently used parameters such as peak to peak of pump flow (QP2P) and pulsation index (PI = QP2P divided by mean pump flow) were calculated.
IQ was speed-independent for both pumps, and correlated well in animal experiments with classical invasively measured contractility index. Simple parameters (QP2P and PI) depended on speed and could be used only for estimation of percentage of support, but not for characterization of cardiac contractility.
In conclusion the cardiac contractility index IQ can be derived from pump flow (IQ) only. It allows easy and noninvasive continuous access to cardiac function.
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© 2009 Springer-Verlag Berlin Heidelberg
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Naiyanetr, P., Moscato, F., Vollkron, M., Zrunek, P., Wieselthaler, G., Schima, H. (2009). Cardiac Contractility Assessment in Rotary Blood Pump Recipients Derived from Pump Flow. In: Dössel, O., Schlegel, W.C. (eds) World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany. IFMBE Proceedings, vol 25/7. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-03885-3_121
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DOI: https://doi.org/10.1007/978-3-642-03885-3_121
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-03884-6
Online ISBN: 978-3-642-03885-3
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