It has long been known that certain antibiotic-producing soil microorganisms are inhibitory to plant pathogens, both in the laboratory and in the field (Stallings 1954). The exploitation of these natural antagonistic interactions has been a driving force in research on the biological control of plant pathogens over the past century, but only in recent decades has pathogen control by antibiotics produced at biologically relevant levels in the environment been demonstrated conclusively. This progress, resulting from conceptual and technological advances made initially in the laboratory and then extended to the field, has set new standards for biocontrol research involving antibiotics. More generally, the approaches used in these studies may be useful in exploring the significance of other bioactive metabolites produced by microorganisms in their native habitats.
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Keywords
- Pseudomonas Fluorescens
- Antibiotic Production
- Appl Environ
- Rhizosphere Microbe
- Veterinary Pharmaceutical
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Thomashow, L.S., Bonsall, R.F., Weller, D.M. (2008). Detection of Antibiotics Produced by Soil and Rhizosphere Microbes In Situ. In: Karlovsky, P. (eds) Secondary Metabolites in Soil Ecology. Soil Biology, vol 14. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-74543-3_2
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