Abstract
Fungi are encountered in two major settings: (1) surface dwellers and colonizers (e.g., mucocutaneous candidiasis and fungus ball, respectively) and (2) infections involving visceral organs/soft tissue. The latter category includes two types of fungi: (1) opportunistic (occurring in immunocompromised host) vs. pathogenic (able to infect immunocompetent host). Classic opportunistic fungi include Pneumocystis and Zygomycetes. Classic pathogenic fungi include dimorphic fungi, which exist as molds in nature and yeast in tissue: Histoplasma, Blastomyces, Coccidioides, and Paracoccidioides. Cryptococcus is predominantly opportunistic. When you encounter a fungus in visceral organs, your DDx should vary according to a patient’s immune status.
By Natasha Rekhtman, Youran Zou, Marina K Baine, Justin A. Bishop
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Rekhtman, N., Baine, M.K., Bishop, J.A. (2019). Potpourri of Quick Morphologic References. In: Quick Reference Handbook for Surgical Pathologists. Springer, Cham. https://doi.org/10.1007/978-3-319-97508-5_14
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DOI: https://doi.org/10.1007/978-3-319-97508-5_14
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