Abstract
The global food demand has been rapidly increasing due to expansion in the worldwide populace resulting in the waning of natural resources. The developed and emerging nations are tapping all means to feed the global population. In a run of these measures, many things brought ecological catastrophes and devastation to many organisms. In our farmlands, most of the crops are affected by a specific class of insects called pests. These pests are feeding on our crops, resulting in the collapsing of our agricultural produce. To save these crops from pests, we manufactured chemicals called pesticides which turned out to be very useful in eradicating the pests. Still, in the meantime, the excessive use of these pesticides brought massive devastation in many ways. Notably, most of the crops are dependent on cross-pollination, carried out by various types of insects. Around 80% of the crops worldwide are pollinated by insects (entomophily), especially the bees and other insect species of different families. But, with the frequent utilization of chemical pesticides, these pollinators and other beneficial insects are severely affected, resulting in a threat to their populations. The utilization of chemical pesticides affects insects, but their negative impact is also noticed in humans, aquatic organisms, birds, soil, water and the environment. So, the phytochemicals in botanical extracts are proven to be very much effective in preventing these dreadful crises due to a positive response by non-target organisms and low impact on our habitats and human health.
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5.1 Introduction
Since time immemorial, man has been cultivating and harvesting crops. Agriculture has consistently assumed a key position in boosting the economy of any country (Loizou et al., 2019). In the present world, agriculture is the chief fount of revenue in the nations engaged with agriculture and other farming sectors (Tang-Péronard et al., 2011). The upsurge in the global population has raised the alarm of food demand rising parallel to the worldwide population. The developed and emerging nations are tapping all means to feed the billions of people across the globe. In pest management practices, the advancement in technology has proven to be accompanying farmers to achieving higher amounts of crop yields. However, in our farmlands, most of the yields are being influenced by a particular class of insects called pests. These pests are feeding on our crops, resulting in the collapsing of most of our agricultural produce. The damage prompted to the crops by insect pests varies on the insect pests’ feeding habit (Table 5.1).
Though crops are affected by abiotic stresses, a significant portion of the crops and the harvest are influenced by the biotic stress of the insect pests. The insect pests can damage an entire or an enormous portion of our crop (Sharma et al., 2017). Around 70% of the crop can be lost to the pests if preventive measures are not taken since several species from different taxa include the natural insect predators and parasitoids that control the population of quite a few pest species. However, with the utilization of chemical pesticides, the natural enemies of the pests are becoming vulnerable. These chemical pesticides assume a significant position in agricultural and horticultural productivity (Carvalho, 2017). Pesticides have been assisting farmers by slashing the time and efforts to expel weeds and pests in farm fields for ages physically. However, due to the growing food demand, the utilization of chemical pesticides has risen enormously. Several environmental contaminations have also emerged with the considerable utilization of chemical pesticides. The soil, water and air quality got widely disrupted by the residues of these chemical pesticides. Life in aquatic ecosystems, beneficial insects and other vegetation became affected by the toxicity of these chemical pesticides (Riyaz et al., 2020).
Thus, to reduce the chemical pesticide contamination, carbon outputs, habitat destruction and fragmentation, sustainable agriculture is an effective alternative. Sustainable agricultural practices are way forward to maintain the ecological equilibrium by the eco-friendly techniques to reverse the damage done by large-scale agriculture and allied farming sectors (Slätmo et al., 2017). With a setup of a green environment and the cultivation of the crops, a lot of eco-friendly practices in sustainable farming can be utilized. These involve permaculture (Bhandari & Bista, 2019), aquaponics and hydroponics (AlShrouf, 2017), using renewable energy resources (Dudin, 2018), crop rotation and polycultures (Weißhuhn et al., 2017) and integrated pest management (Dara, 2019) (Fig. 5.1). With these practices, natural resource exploitation can be curbed. Further, diversification in the crops by crop rotation and polycultures can reduce fertilizers and pesticides. Chemical pesticides can be replaced by botanical pesticides, which are safer to handle and assure a low impact on the species of different taxa, their habitats, different ecosystems and human health (Nawaz, Juma, & Hongxia, 2016).
By introducing sustainable agricultural practices, the innovative technologies have progressed well to conserve the environment, beneficial insect diversity and human health. For eliminating the pests from farmlands, plant extracts are a creative and safe approach. The extracts can be obtained from dried or ground plant materials or crude plant. These plant extracts have been proven to be the best alternative to chemical pesticides as they can remove the pests from the farm fields while improving the quality of soil, water and air by their low impact. The plant extracts used as insecticides have a remarkable place among sustainable agriculture practices as they are safer than synthetic pesticides. In this chapter, sustainability of agriculture, botanical pesticides, their sources, usage, new challenges, prospects and effects of chemical pesticides on beneficial insect diversity, human health and aquatic ecosystems have been addressed in a detailed manner (Isman & Grieneisen, 2014).
5.2 Sustainable Agriculture: A Promise to the Future
Back in the 1970s till now, there has been an enormous rise in environmental devastation brought about by the widespread agricultural activities (Majeed & Mazhar, 2019). Around 12% of the global greenhouse gas emissions are contributed by the activities such as industrial agriculture and other environmental devastations such as deforestation, habitat destruction, pesticide toxification and pollution, and intense carbon outputs caused the large-scale agribusinesses (Yue et al., 2017). Soil erosion can also be triggered by higher demands of agriculture on natural ecosystems (Nearing et al., 2017). There has been a rise in agricultural practices for a higher food demand as well, and for achieving a good result, the crops have been fertilized and sprayed with pesticides to save them from any pest damages. Safeguarding of these crops is only possible when we frequently splash them with pesticides, thereby achieving a good harvest. However, it has such severe implications on the environment and human health. For a good harvest to accomplish without menacing the soil, water, human wellbeing and the surrounding ecosystems, there is a need for eco-friendly and sustainable agriculture.
According to the Food and Agriculture Organization (FAO) of the United Nations, sustainability in agricultural development can be defined as ‘the management and conservation of the natural resource base, and the orientation of technological change in such a manner, to ensure the attainment of continued satisfaction of human needs for present and future generations’ (FAO, 2014). Sustainable farming becomes more substantial among the developed and developing nations engaged in the agriculture sectors (Roberts & Mattoo, 2018). The deployment of sustainable agricultural practices into the farming sectors has proven to an innovative approach towards conserving natural resources like aquatic and terrestrial ecosystems, safeguarding the environment, human health and beneficial insect diversity, including pollinators and natural predators (Saunders, 2018). Sustainable agricultural practices aim to achieve higher crop yields, thus obtaining higher economic profitability (Fig. 5.2). With the advancement in technology, modern techniques can be employed in sustainable agriculture by which eco-friendly practices can be carried out so that there is the least wastage of harvest and natural resources. In sustainable agriculture, not only can we conserve our environment and natural resources but also train and exercise optimization of the usage of pesticides and fertilizers. The farmers implementing sustainable agriculture practices can achieve a higher crop yield and conserve their surrounding ecosystems contaminated by pesticide residues. Dealing with the pests in an agroecosystem and implementing integrated pest management (IPM) in sustainable agriculture are ways forward for dealing with the pests and eventually safeguarding human and environmental health. Integrated pest management (IPM) has emerged as the most ecosystem-based strategy for protecting crop and vegetable cultivations. With IPM, an aggregation of techniques can be employed such as biological, cultural, manual and chemical by implementing resistant varieties of crops and habitat management through which economic, health and environmental risk can be reduced (Peterson et al., 2018).
5.3 The Growing Pest Emergence, Problem and Utilization of Chemical Pesticides
The lower Devonian period marked the dawn of insect evolution. Because of their capability to withstand a wide range of climatic conditions, these species became the dominant creatures the planet has ever witnessed. The insects are the primary animals on the earth that adapted the flight capability, back around 400 million years ago, and dominated all the world’s ecosystems (Riyaz et al., 2018). The flight ability provided immense support to the insect body for grabbing an edge over others and to get acclimatized in every nook and corner of the earth. The ability to flourish in different environmental conditions with flexible body parts helped these animals conquer even the limits of idiosyncratic environmental conditions. The arthropodic origin of insects and their power and life inside invertebrate phyla made them profoundly successful creatures of this planet. While insects flourished in the animal kingdom as dominating creatures, these creatures deliver several ecosystem services to the humankind and their world in a unique style. The pollens got shipped through cross-pollination by flying cargos of insects, and around 80% of crops across the globe are depending on the insects for transportation of their pollen from one flower to the other (McGregor, 1976). The insects have marked a natural establishment across all global ecosystems. Besides rendering the services like nutrient cycling, seed dispersal, fertility and structure of the soil, they are also proven to be a significant food source for other taxa. With all these characteristic roles they play in an ecosystem, a portion of insects turns out to be pests of many crops around the world. Saving the crop yield from the nuisances, there has been a progression in controlling these pests from time to time.
Along with the rise of agriculture in the ancient world, the eradication of the pests came on track back in 3000 BC, when ancient Egyptians employed trained cats and mongooses for controlling the pests of stored grains such as rodents and back in 500 AD in Europe when Ferrets were trained as mousers (Sherman, 2007; Taylor, 2011). Since it was simple to pulverize weeds in the farm fields by either blazing them or by tilling them out. However, with time and safeguarding crops, the ancient Sumerians utilized pesticides before 2000 BC (Pflanzenschutz-Nachrichten, 1973). Essential sulphur dusting was a conspicuously known pesticide and a key component utilized in ancient occasions around 4500 years back before Mesopotamia (Ranga Rao et al., 2007). Till the fifteenth century, toxic synthetic compounds, such as arsenic, mercury and lead, were sprinkled on yields for removing the nuisances. During the seventeenth century, nicotine sulphate from tobacco leaves was removed and utilized as a bug spray (Miller, 2002). With the disclosure of the insecticidal properties of DDT by Paul Muller in 1939, synthetic pesticides began to advance in the market. In 1948, he conceded the Nobel Prize to discover pesticide properties of DDT (Peshin et al., 2009). Eventually, in the 1960s, problems like the resistance of pests to chemicals, threat to biodiversity, aquatic and terrestrial ecosystems, climate and environment began to rise.
5.4 Erroneous Effects of Chemical Pesticides in Agriculture: Hazards to Human Health, Insect Biodiversity and Aquatic Ecosystem
‘For the first time in the history of the world, every human being is now subjected to contact with dangerous chemicals, from the moment of conception until death’ (Rachel Carson, 1962).
Pesticides are the chemical compounds developed for eliminating pests from agricultural fields, storage warehouses, homes, etc. Since time immemorial, man has been utilizing pesticides because their utilization has brought relief to farmers by expelling the pests from the farmlands. However, the large-scale usage of chemical pesticides has proven to be incompatible with the environment. Pesticides are generally used to remove insect pests (insecticides), fungi (fungicides), rodents (rodenticides), unwanted plants/weeds (herbicides/weedicides), nematodes (nematicides) and bacteria (bactericides) (Fig. 5.3). The impact of chemical pesticides on various life forms and different ecosystems has been reported across different world places. The nations engaged in different agricultural and allied sectors are mostly affected by it. With the rise in global population and food requirements, there has been a parallel growth in the large-scale cultivation of high-yielding monocrops. Since crop loss by the pests was controlled by the pesticides, their long-lasting adverse impact on various life forms and the natural environment is a significant challenge to be taken care of. On the contrary, the health of farmers has also declined due to their exposure to the toxicity levels of chemical pesticides. The chemical pesticides have been most devastative on beneficial insect diversity, including pollinators such as honey bees, dipteran pollinators, predators, parasitoids and other useful insects that deliver several ecosystem services. In an agricultural field, several insects can be seen collecting nectar and pollinating the flowers, such as bees, wasps, hoverflies, moths and butterflies and some species checking the populations of insect pests such as parasitic wasps, hornets, beetles, lacewings, etc. While spraying the pesticides (Fig. 5.4) on crops infested with pests, 15 to 40% of an estimated fraction of pesticides are scattered into the atmosphere by either volatilization or spray drift processes (Socorro et al., 2016). After spraying, the pesticides in the atmospheric particulate phase remain in the air for about 7 to 12 days and thoroughly orbit many geographical locations worldwide. The circling of pesticides in the atmosphere alters the air quality and adds more events to climate change (Miller & Spoolman, 1996). The pesticide runoff from the agricultural lands into streams and lakes significantly impacts aquatic life and water contamination. Though runoff can transport pesticides into the aquatic ecosystem, the atmospheric dispersal of pesticides can travel to other places like grazing fields and human settlements, potentially affecting other living organisms and human wellbeing (Fig. 5.5). The impact of synthetic agrochemicals on insect diversity has been well documented across the globe, and there has been a massive decline in insect pollinators from the past few decades due to the large-scale pesticide utilization (; Dudley & Alexander, 2017; Sánchez-Bayo & Wyckhuys, 2019). Some studies have shown that compounds of organophosphates and other pesticides can have poisonous or lethal effects resulting in the disruptions of cellular metabolism that often lead to embryonic changes and mutagenesis (Maurya et al., 2019) on fish species and birds (Tesfahunegny, 2016). Besides the impact of pesticides on the environment (Mahmood et al., 2016), soil (Joko et al., 2017) and water (de Souza et al., 2020; Hallberg, 1987), reports of pesticides influencing wildlife (Moriarty, 1972; Rattner, 2009), amphibians (Islam & Malik, 2018; McCoy & Peralta, 2018), earthworms (Yasmin & D’Souza, 2010), non-target plants (Mitra & Raghu, 1998; Saladin & Clément, 2005) and grazing animals (Choudhary et al., 2018) have also been well documented in the recent past (Fig. 5.6). Many studies worldwide have reported several health-related issues such as brain cancers, breast cancers, testis and ovarian cancers, leukaemias and lymphomas affecting people. A detailed list of health issues and diseases of humans caused by the exposure and poisoning of synthetic pesticides and their classification is given in Table 5.2.
5.5 Botanical Pesticides: A Natural Alternative for Chemical Pesticides
Synthetic pesticides are utilized as a swift remedy to the threat caused by pests in all stages of crop production (Ekeh et al., 2018). They include a wide range of chemicals that are non-biodegradable and persistent, polluting water, air and soil, leading to unintentional hazards to humans, non-target species and the environment, including depletion of the ozone layer (Damalas & Koutroubas, 2015; Lengai et al., 2020; Wimalawansa & Wimalawansa, 2014). Uncontrolled and continuous use of synthetic pesticides can also induce pesticide resistance among pest populations and pest resurgence, yet another disastrous factor in pest management (Shabana et al., 2017). These erroneous human health issues and drastic effects on nature and biodiversity invoked the thought for an alternative (Mahmood et al., 2016). Botanical extracts are biochemical compounds extracted from different plants, biodegradable with lesser shelf life, making them nature-friendly. Plant extracts were used in various fields by human life since time immemorial in many civilizations throughout the history in China, Egypt, Greece and India (Dougoud et al., 2019). The pesticide properties of botanical extracts have shown promising results, making them suitable candidates for integrated pest management (b; Ali et al., 2014; Isman, 2017a; Isman & Grieneisen, 2014; Mkenda et al., 2015; Stevenson et al., 2017). Due to their special attributes like lower toxicity, biodegradability, diverse modes of action, efficacy and obtainability of source materials, botanical pesticides are of greater importance from planting to harvesting and storing crops (Neeraj et al., 2017).
5.5.1 Source of Botanical Pesticides
Botanical pesticides are extracted from plant sources that can kill or control pests (Chengala & Singh, 2017). Every plant in nature has developed certain natural mechanisms in evolution to adapt to various environmental conditions with their pesticide property as one among them. A worldwide estimate of more than 2500 species of plants from 235 families has been noted to possess biochemical with pesticide or deterrent or growth-regulating properties (Das, 2014; Roy et al., 2016). Major plant families with active biomolecules against pests include Apiaceae, Apocynaceae, Asteraceae, Cupressaceae, Caesalpinaceae, Lamiaceae, Lauraceae, Liliaceae, Myrtaceae, Piperaceae, Poaceae, Rutaceae, Sapotaceae, Solanaceae, Zingiberaceae, etc. (Ahmad et al., 2017; Wanzala et al., 2016).
A wide range of common and locally available plants have also been reported to possess some pesticidal biochemical compounds like A. indica (neem), Tanacetum cinerariifolium (pyrethrum), Allium sativum (garlic), Curcuma longa (turmeric), Rosmarinus officinalis (rosemary), Zingiber officinale (ginger) and Thymus vulgaris (thyme) (Castillo-Sánchez, Jiménez-Osornio, Delgado-Herrera , Candelaria-Martínez, & Sandoval-Gío, Castillo-Sánchez et al., 2015). Compounds like azadirachtin from neem and pyrethrin from pyrethrum are common examples of isolated botanicals that have been commercialized due to their efficient results (Kumar et al., 2015). Selected examples of botanical pesticides against different pest groups are shown in Table 5.3.
The plant part used for extraction depends on the bioactive compound of interest and its concentration in a particular plant part, including root, rhizome, stem, bark, leaves, flower, fruit, seeds and cloves (Lengai et al., Lengai et al., 2020). The extraction and production of these botanical pesticides are economical and straightforward compared to synthetic pesticides, emitting large amounts of toxic pollutants as by-products or wastes. The process generally involves grinding of dried plant parts followed by extraction using organic solvents that maximize the extraction of target compounds (Chougule & Andoji, 2016). The extract is then concentrated, formulated and tested for evaluation in the lab and field trials (Zarubova et al., 2014).
5.5.2 Benefits of Botanical Pesticides over Synthetic Pesticides
The vast availability of source plants, diverse uses, less toxicity to non-specific targets like pollinators and fish, cheaper costs, effectiveness and reliability are the attributes responsible for the acceptability of the botanical pesticides in sustainable crop production (Castillo-Sánchez et al., 2015; Srijita, 2015). Botanical pesticides have been demonstrated to possess insecticidal properties even in their crude forms (Ali et al., 2014). Target specificity of compounds in plant extracts and essential oils ensures safeguarding non-target species and, more importantly, beneficial species like pollinators and natural predators (Nawaz, Mabubu, & Hua, 2016). The pesticide-pest interaction of botanical pesticides is biochemical, thereby decreasing the probability of pesticide resistance (Lengai et al., 2020). The efficacy of botanical pesticides can be influenced by parameters like a source of plant species, the raw material (fresh or dried) used for extraction, extraction methodology and solvents utilized for extraction (Arafat et al., 2015; Sarkar & Kshirsagar, 2014). Compared to synthetic pesticides, botanical pesticides show diverse modes of action like toxicity, repellence, growth regulation and structural modifications on target species, making them the best fit for integrated pest management (Laxmishree & Nandita, 2017). Botanical extracts, especially metabolites, can interfere with insect behaviour, morphology, metabolic pathways, biochemical processes and physiological activities; blocking of glucose in chemosensory receptor cells in the mouth of lepidopterans by terpenes and chemosterilant activity of some essential oils are a few examples (Lengai et al., 2020).
Utilization of botanical pesticides in pest control guarantees added benefits to farmers like food security, lowering pest intensities and enhanced superiority of harvest, drawing greater demands and higher rates in the market (Nefzi et al., 2016). Organically produced food products are in greater demand in the lucrative market, where consumers are ready to buy these foods at higher rates creating greater market openings for botanical pesticides (Misra, 2014).
5.5.3 Biodegradability of Botanical Pesticides
The botanical pesticides are quickly degraded, with their biological origin preventing their accumulation in the environment and thereby eliminating the chances of air, water and soil pollution (Sokovi’ c, 2010). Exposure to sunlight, high temperature and humidity could break down their constituents depending on their nature, e.g. azadirachtin, isolated from neem (A. indica), has a half-life between 1 day over crops and 2 days in soil, whereas thymol, a compound extracted from Piper nigrum, Satureja hortensis, Thymus vulgaris and Zataria multiflora under sunlight, is proved to survive up to 28 hours to degrade and in soil with a duration of 8 days (Liu et al., 2017; Yan et al., 2017; Yang et al., 2017). The biodegradation process is accelerated by detoxification enzymes secreted by microorganisms present in abundance in natural conditions through oxidative metabolism (Mpumi et al., 2016). Carboxylesterase enzyme-mediated hydrolysis of ester bonds is a common pathway of biodegradation exhibited by microorganisms such as Bacillus cereus and Aspergillus niger (Cycoń & Piotrowska-Seget, 2016). A wide variety of bacterial species are reported to degrade carbamates, organophosphates, organochlorine pesticides and pyrethroids (Cycoń & Piotrowska-Seget, 2016; Porto et al., 2011).
In soil, enzymes produced by microorganisms modify the botanical pesticides into less toxic groups that are breakable, rendering them biologically unavailable and making them non-toxic (Ortiz-Hernández et al., 2013). Microbial degradation is further influenced by physical factors and interaction with pesticides and environmental conditions (Cycoń & Piotrowska-Seget, 2016).
5.5.4 Botanical Pesticides for Integrated Pest Management
Integrated pest management (IPM) aims to achieve sustainable pest management through environment-friendly strategies for reducing pests and attaining highly profitable yields (Alam et al., 2016). Botanical pesticides are eco-friendly natural compounds effective against different pests like viruses, bacteria, fungi, nematodes and insects with varied modes of action (Feyisa et al., 2015; Todorov et al., 2015). Alongside crop , security approaches like host plant resistance or tolerance, the introduction of natural enemies like parasitoids and predators, improved agricultural practices, use of microbial pesticides and reduced use of chemical pesticides, application of botanical pesticides also serve as a critical component in IPM (Muthomi et al., 2017; Wegulo et al., 2015). Compounds extracted from plant sources are effective against a major group of pests like viruses, bacteria, fungi, nematodes and insects (Elbeshehy et al., 2015; Ingle et al., 2017; Neeraj et al., 2017; Sales et al., 2016; Salhi et al., 2017). This wide variety of botanical pesticides and their results using crude form, extractions and formulations opens a wide scope for complete replacement of synthetic pesticide with these eco-friendly pesticides, which immensely contributes to integrated pest management and sustainable agriculture for a healthy future (Fig. 5.7).
5.6 Prospects of Botanical Pesticides: Discussion and Conclusion
The large-scale utilization of chemical pesticides has affected the pollinators and other beneficial insects, but its negative impacts have also been noticed on human health, aquatic organisms, birds, wildlife, grazing animals, earthworms, soil, air, water and the environment. The phytochemicals in botanical extracts are proven to be much effective in preventing these dreadful crises due to a positive response by non-target organisms and low impact on the environment and human health. Even with great scope, botanical pesticides are not much represented in the pesticide market (Kekuda et al., 2016). Plants that are being used for food are less preferred for pesticide production by farmers due to a greater demand for food security (Srijita, 2015). Farmers have shown interest in synthetic pesticides over botanicals due to their unrestricted availability and established production facilities, leading to cheaper rates in the market, longer shelf life and simpler application methods (Lengai et al., 2020). Little awareness among farmers, complex regulatory procedures for production, chances of biodegradability with physical factors, reported rare side effects on non-target species, dependency on extraction methodology for promising results, etc. diminish the presence of botanical pesticides in agricultural fields, which needs to be addressed with comprehensive future research (Ekpo et al., 2017; Okunlola & Akinrinnola, 2014; Sales et al., 2016; Stevenson & Belmain, 2017).
In light of these facts, the governments by implementing agricultural laws utilizing natural pesticides in economic ways for farmers could bring around eco-friendly farming practices. Considering the drastic effects of synthetic pesticides and the benefits of botanical pesticides, it is an environmental emergency to replace synthetic pesticides with botanicals and other organic pesticides. With technological advancements and the exploration of more plants with pesticide effects, botanical pesticides could eventually replace synthetic pesticides for safer, environment-friendly and sustainable agriculture soon. This could also bring about the use of these plants and plant products as a source of income for many societies, especially the rural and tribal, which will direct towards eradicating unemployment and sustainable utilization of available natural resources contributing to the development of the country and humanity.
References
Abtew, A., Subramanian, S., Cheseto, X., Kreiter, S., Garzia, G. T., & Martin, T. (2015). Repellency of plant extracts against the legume flower thrips Megalurothrips sjostedti (Thysanoptera: Thripidae). Insects, 6(3), 608–625. https://doi.org/10.3390/insects6030608
Agriculture Organization (Ed.). (2014). Opportunities and challenges. Food and agriculture org. State of World Fisheries and Aquaculture, 2014.
Ahmad, W., Shilpa, S., & Sanjay, K. (2017). Phytochemical screening and antimicrobial study of Euphorbia hirta extracts. Journal of Medicinal Plants Studies, 2, 183–186.
Alam, M. Z., Haque, M. M., Islam, M. S., Hossain, E., Hasan, S. B., Hasan, S. B., & Hossain, M. S. (2016). Comparative study of integrated pest management and farmers practices on sustainable environment in the rice ecosystem. International Journal of Zoology, 2016, 1–12. https://doi.org/10.1155/2016/7286040
Ali, S., Muhammad, S. M. H., Muneer, A., Faisal, H., Muhammad, F., Dilbar, H., … Abdul, G. (2014). Insecticidal activity of turmeric (Curcuma longa) and garlic (Allium sativum) extracts against red flour beetle, Tribolium castaneum: A safe alternative to insecticides in stored commodities. Journal of Entomology and Zoology Studies, 3, 201–205.
AlShrouf, A. (2017). Hydroponics, aeroponic and aquaponic as compared with conventional farming. American Scientific Research Journal for Engineering, Technology and Sciences (ASRJETS), 27(1), 247–255.
Arafat, Y., Shahida, K., Wenxiong, L., Changxun, F., Sehrish, S., Niaz, A., & Saadia, A. (2015). Allelopathic evaluation of selected plants extract against broad and narrow leaves weeds and their associated crops, Acad. Journal of Agricultural Research, 10, 226–234.
Badr, A. M. (2020). Organophosphate toxicity: Updates of malathion potential toxic effects in mammals and potential treatments. Environmental Science and Pollution Research International, 27(21), 26036–26057. https://doi.org/10.1007/s11356-020-08937-4
Baron, R. L., & Merriam, T. L. (1988). Toxicology of aldicarb. In Reviews of environmental contamination and toxicology (Vol. 105, pp. 1–70). Springer. https://doi.org/10.1007/978-1-4612-3876-8_1
Bates, L., Clifford, H., Coyle, R., Ertz, S., McClure, V., McKenzie, A., . . . Butler, C. D. (2008). Dieldrin and breast cancer: A literature [review], 1–22.
Beane Freeman, L. E., Bonner, M. R., Blair, A., Hoppin, J. A., Sandler, D. P., Lubin, J. H., … Alavanja, M. C. (2005). Cancer incidence among male pesticide applicators in the agricultural health study cohort exposed to diazinon. American Journal of Epidemiology, 162(11), 1070–1079. https://doi.org/10.1093/aje/kwi321
Bhandari, D., & Bista, B. B. (2019). Permaculture: A key driver for sustainable agriculture in Nepal. International Journal of Applied Sciences and Biotechnology, 7(2), 167–173. https://doi.org/10.3126/ijasbt.v7i2.24647
Byard, J. L., Paulsen, S. C., Tjeerdema, R. S., & Chiavelli, D. (2015). DDT, chlordane, toxaphene and PCB residues in Newport Bay and watershed: Assessment of hazard to wildlife and human health. In Reviews of environmental contamination and toxicology (Vol. 235, pp. 49–168). Springer. https://doi.org/10.1007/978-3-319-10861-2_3
Carson, R. (1962). Silent spring (1st ed.). Houghton Mifflin Harcourt.
Carvalho, F. P. (2017). Pesticides, environment, and food safety. Food and Energy Security, 6(2), 48–60. https://doi.org/10.1002/fes3.108
Castillo-Sánchez, L. E., Jiménez-Osornio, J. J., Delgado-Herrera, M. A., Candelaria-Martínez, B., & Sandoval-Gío, J. J. (2015). Effects of the hexanic extract of neem Azadirachta indica against adult whitefly Bemisia tabaci. Journal of Entomology and Zoology Studies, 5, 95–99.
Chen, G. (2014). Methoxychlor. In P. Wexler (Ed.), Encyclopedia of toxicology (3rd ed., pp. 254–255). Academic Press.
Chengala, L., & Singh, N. (2017). Botanical pesticides—A major alternative to chemical pesticides: A review. International Journal of Life Sciences, 5(4), 722–729.
Choudhary, S., Yamini, N. R., Yadav, S. K., Kamboj, M., & Sharma, A. (2018). A review: Pesticide residue: Cause of many animal health problems. Journal of Entomology and Zoology Studies, 6(3), 330–333.
Chougule, P. M., & Andoji, Y. S. (2016). Antifungal activity of some common medicinal plant extracts against soil borne phytopathogenic fungi Fusarium oxysporum causing wilt of tomato. International Journal of Development Research, 6(3), 7030–7033.
Cohn, B. A., La Merrill, M., Krigbaum, N. Y., Yeh, G., Park, J. S., Zimmermann, L., & Cirillo, P. M. (2015). DDT exposure in utero and breast cancer. Journal of Clinical Endocrinology and Metabolism, 100(8), 2865–2872. https://doi.org/10.1210/jc.2015-1841
Cook, M. B., Trabert, B., & McGlynn, K. A. (2011). Organochlorine compounds and testicular dysgenesis syndrome: Human data. International Journal of Andrology, 34(4 pt. 2), e68–e84; discussion e84. https://doi.org/10.1111/j.1365-2605.2011.01171.x
Cycoń, M., & Piotrowska-Seget, Z. (2016). Pyrethroid-degrading microorganisms and their potential for the bioremediation of contaminated soils: A review. Frontiers in Microbiology, 7, 1463. https://doi.org/10.3389/fmicb.2016.01463
Damalas, C. A., & Koutroubas, S. D. (2015). Farmers’ exposure to pesticides: Toxicity types and ways of prevention. Toxics, 1, 1–10.
Dara, S. K. (2019). The new integrated pest management paradigm for the modern age. Journal of Integrated Pest Management, 10(1), 12. https://doi.org/10.1093/jipm/pmz010
Das, S. K. (2014). Recent development and future of botanical pesticides in India. Popular Kheti, 2(2), 93–99.
de Souza, R. M., Seibert, D., Quesada, H. B., de Jesus Bassetti, F., Fagundes-Klen, M. R., & Bergamasco, R. (2020). Occurrence, impacts and general aspects of pesticides in surface water: A review. Process Safety and Environmental Protection, 135, 22–37. https://doi.org/10.1016/j.psep.2019.12.035
Dewan, A., Patel, A. B., Pal, R. R., Jani, U. J., Singel, V. C., & Panchal, M. D. (2008). Mass ethion poisoning with high mortality. Clinical Toxicology, 46(1), 85–88. https://doi.org/10.1080/15563650701517251
Doi, H., Kikuchi, H., Murai, H., Kawano, Y., Shigeto, H., Ohyagi, Y., & Kira, J. (2006). Motor neuron disorder simulating ALS induced by chronic inhalation of pyrethroid insecticides. Neurology, 67(10), 1894–1895. https://doi.org/10.1212/01.wnl.0000244489.65670.9f
Dougoud, J., Toepfer, S., Bateman, M., & Jenner, W. H. (2019). Efficacy of homemade botanical insecticides based on traditional knowledge. A review. Agronomy for Sustainable Development, 39(4), 37. https://doi.org/10.1007/s13593-019-0583-1
Dudin, M. (2018). Renewable energy sources as an instrument to support the competitiveness of agro-industrial enterprises and reduce their costs.
Dudley, N., Attwood, S. J., Goulson, D., Jarvis, D., Bharucha, Z. P., & Pretty, J. (2017). How should conservationists respond to pesticides as a driver of biodiversity loss in agroecosystems? Biological Conservation, 209, 449–453. https://doi.org/10.1016/j.biocon.2017.03.012
Edwards, F. L., & Tchounwou, P. B. (2005). Environmental toxicology and health effects associated with methyl parathion exposure–a scientific review. International Journal of Environmental Research and Public Health, 2(3–4), 430–441. https://doi.org/10.3390/ijerph2005030007
Ekpo, P. B., Uno, U. U., Effiong, E. C., & Etta, S. E. (2017). Acute toxicity of Tephrosia vogelli on the early life stages of farmed clariid. (Clarias gariepinus) Asian J. Adv. Agricultural Research, 3(2), 1–5.
Elbeshehy, E. K. F., Metwali, E. M. R., & Almaghrabi, O. A. (2015). Antiviral activity of Thuja orientalis extracts against watermelon mosaic virus (WMV) on Citrullus lanatus. Saudi Journal of Biological Sciences, 22(2), 211–219. https://doi.org/10.1016/j.sjbs.2014.09.012
Evangelou, E., Ntritsos, G., Chondrogiorgi, M., Kavvoura, F. K., Hernández, A. F., Ntzani, E. E., & Tzoulaki, I. (2016). Exposure to pesticides and diabetes: A systematic review and meta-analysis. Environment International, 91, 60–68. https://doi.org/10.1016/j.envint.2016.02.013
Fent, G. M. (2014). Disulfoton. In P. Wexler (Ed.), Encyclopedia of toxicology (3rd ed., pp. 210–211). Academic Press.
Feyisa, B., Lencho, A., Selvaraj, T., & Getaneh, G. (2015). Evaluation of some botanicals and Trichoderma harzianum for the management of tomato root-knot nematode (meloidogyne incognita (Kofoid and white) chit wood). Advances in Crop Science and Technology, 1, 1–10.
Gupta, R. C., & Milatovic, D. (2014). Insecticides. In R. C. Gupta (Ed.), Biomarkers in toxicology (pp. 389–407). Academic Press.
Gupta, R. C. (1994). Carbofuran toxicity. Journal of Toxicology and Environmental Health, 43(4), 383–418. https://doi.org/10.1080/15287399409531931
Hallberg, G. R. (1987). The impacts of agricultural chemicals on ground water quality. GeoJournal, 15(3), 283–295. https://doi.org/10.1007/BF00213456
Harchegani, A. B., Rahmani, A., Tahmasbpour, E., Kabootaraki, H. B., Rostami, H., & Shahriary, A. (2018). Mechanisms of diazinon effects on impaired spermatogenesis and male infertility. Toxicology and Industrial Health, 34(9), 653–664. https://doi.org/10.1177/0748233718778665
Honeycutt, M., & Jones, L. (2014). Endrin. In P. Wexler (Ed.), Encyclopedia of toxicology (3rd ed., pp. 344–347). Academic Press.
Igbinosa, E. O., Odjadjare, E. E., Chigor, V. N., Igbinosa, I. H., Emoghene, A. O., Ekhaise, F. O., … Idemudia, O. G. (2013). Toxicological profile of chlorophenols and their derivatives in the environment: The public health perspective. The Scientific World Journal, 2013, 460215. https://doi.org/10.1155/2013/460215
Ingle, K. P., Deshmukh, A. G., Padole, D. A., Dudhare, M. S., Moharil, M. P., & Khelurkar, V. C. (2017). Bioefficacy of crude extracts from Jatropha curcas against Spodoptera litura. Journal of Entomology and Zoology Studies, 1, 36–38.
Islam, A., & Malik, M. F. (2018). Impact of pesticides on amphibians: A review. Journal of Analytical Toxicology, 1(2), 3.
Isman, M. B. (2017a). Bridging the gap: Moving botanical insecticides from the laboratory to the farm. Industrial Crops and Products, 110, 10–14. https://doi.org/10.1016/j.indcrop.2017.07.012
Isman, M. B., & Grieneisen, M. L. (2014). Botanical insecticide research: Many publications, limited useful data. Trends in Plant Science, 19(3), 140–145. https://doi.org/10.1016/j.tplants.2013.11.005
Isman, M. B. (2017b). Bridging the gap: Moving botanical insecticides from the laboratory to the farm. Industrial Crops and Products, 110, 10–14. https://doi.org/10.1016/j.indcrop.2017.07.012
Jantasorn, A., Boontida, M., & Tida, D. (2016). In vitro antifungal activity evaluation of five plant extracts against five plant pathogenic fungi causing rice and economic crop diseases. Journal of Biopesticides, 1, 1–7.
Jnaid, Y., Yacoub, R., & Al-Biski, F. (2016). Antioxidant and antimicrobial activities of Origanum vulgare essential oil. International Food Research Journal, 4, 1706–1710.
Joko, T., Anggoro, S., Sunoko, H. R., & Rachmawati, S. (2017). Pesticides usage in the soil quality degradation potential in wanasari subdistrict, Brebes, Indonesia. Applied and Environmental Soil Science, 2017, 1–7. https://doi.org/10.1155/2017/5896191
Kekuda, P. T. R., Akarsh, S., Nawaz, S. A. N., Ranjitha, M. C., Darshini, S. M., & Vidya, P. (2016). In vitro antifungal activity of some plants against Bipolaris sarokiniana (Sacc.) Shoem. International Journal of Current Microbiology and Applied Sciences, 6, 331–337.
Kepenekçi, I., & Erdo. (2016). ˘gu¸s D, Erdo ˘gan P. effects of some plant extracts on root-knot nematodes in vitro and in vivo conditions, Turk. Journal of Entomology, 40(1), 3–14.
Khanjani, N., Hoving, J. L., Forbes, A. B., & Sim, M. R. (2007). Systematic review and meta-analysis of cyclodiene insecticides and breast cancer. Journal of Environmental Science and Health. Part C, Environmental Carcinogenesis and Ecotoxicology Reviews, 25(1), 23–52. https://doi.org/10.1080/10590500701201711
Kim, K. H., Kabir, E., & Jahan, S. A. (2017). Exposure to pesticides and the associated human health effects. Science of the Total Environment, 575, 525–535. https://doi.org/10.1016/j.scitotenv.2016.09.009
Koshlukova, S., & Reed, N. (2014). Carbaryl. In: Richardson RJ (ed) Encyclopedia of toxicology, 3rd. Elsevier, Amsterdam, pp 668–672.
Koutros, S., Mahajan, R., Zheng, T., Hoppin, J. A., Ma, X., Lynch, C. F., … Alavanja, M. C. (2008). Dichlorvos exposure and human cancer risk: Results from the agricultural health study. Cancer Causes and Control, 19(1), 59–65. https://doi.org/10.1007/s10552-007-9070-0
Kumar, M. M., Kumar, S., Prasad, C. S., & Kumar, P. (2015). Management of gram pod borer, Helicoverpa armigera (Hubner) in chickpea with botanical and chemical insecticide. Journal of Experimental Zoology India, 18(2), 741.
Laxmishree, C., & Nandita, S. (2017). Botanical pesticides –a major alternative to chemical pesticides: A review. International Journal of Life Sciences, 4, 722–729.
Lengai, G. M. W., Muthomi, J. W., & Mbega, E. R. (2020). Phytochemical activity and role of botanical pesticides in pest management for sustainable agricultural crop production. Scientific African, 7, e00239. https://doi.org/10.1016/j.sciaf.2019.e00239
Lewis, K. A., Tzilivakis, J., Warner, D. J., & Green, A. (2016). An international database for pesticide risk assessments and management. Human and Ecological Risk Assessment: An International Journal, 22(4), 1050–1064. https://doi.org/10.1080/10807039.2015.1133242
Lim, J. E., Park, S. H., Jee, S. H., & Park, H. (2015). Body concentrations of persistent organic pollutants and prostate cancer: A meta-analysis. Environmental Science and Pollution Research International, 22(15), 11275–11284. https://doi.org/10.1007/s11356-015-4315-z
Liu, B., Chen, B., Zhang, J., Wang, P., & Feng, G. (2017). The environmental fate of thymol, a novel botanical pesticide, in tropical agricultural soil and water. Toxicological and Environmental Chemistry, 99(2), 223–232. https://doi.org/10.1080/02772248.2016.1198907
Loizou, E., Karelakis, C., Galanopoulos, K., & Mattas, K. (2019). The role of agriculture as a development tool for a regional economy. Agricultural Systems, 173(173), 482–490. https://doi.org/10.1016/j.agsy.2019.04.002
Loomis, D., Guyton, K., Grosse, Y., El Ghissasi, F., Bouvard, V., Benbrahim-Tallaa, L., … International Arctic Research Center, Monograph Working Group. Carcinogenicity of lindane. (2015). Carcinogenicity of lindane, DDT, and 2,4-dichlorophenoxyacetic acid. Lancet Oncology, 16(8), 891–892. https://doi.org/10.1016/S1470-2045(15)00081-9
Mahmood, I., Imadi, S. R., Shazadi, K., Gul, A., & Hakeem, K. R. (2016). Effects of pesticides on environment. In Plant, soil and microbes (pp. 253–269). Springer.
Majeed, M. T., & Mazhar, M. (2019). Environmental degradation and output volatility: A global perspective. Pakistan Journal of Commerce and Social Sciences (PJCSS), 13(1), 180–208.
Maurya, P. K., Malik, D. S., & Sharma, A. (2019). Impacts of pesticide application on aquatic environments and fish diversity. Contaminants in Agriculture and Environment: Health Risks and Remediation, 1, 111.
McCoy, K. A., & Peralta, A. L. (2018). Pesticides could alter amphibian skin microbiomes and the effects of Batrachochytrium dendrobatidis. Frontiers in Microbiology, 9, 748. https://doi.org/10.3389/fmicb.2018.00748
McGregor, S. E. (1976). Insect pollination of cultivated crop plants. Agricultural Research Service.
Miller, G. (2002). Living in the environment (12th ed.). Thomson Learning.
Miller, G. T., & Spoolman, S. (1996). Living in the environment: Principles. Connections, and solutions. Wodsworth.
Mirajkar, N. S. (2014). Dimethoate. In P. Wexler (Ed.), Encyclopedia of toxicology (3rd ed., pp. 55–157). Academic Press.
Misra, H. P. (2014). Role of botanicals, biopesticides and bioagents in integrated pest management, Odisha. Rev, 62–67.
Mitra, J., & Raghu, K. (1998). Pesticides-non target plants interactions: An overview. Archives of Agronomy and Soil Science, 43(6), 445–500. https://doi.org/10.1080/03650349809366059
Mkenda, P. A., Stevenson, P. C., Ndakidemi, P., Farman, D. I., & Belmain, S. R. (2015). Contact and fumigant toxicity of five pesticidal plants against Callosobruchus maculatus (Coleoptera: Chrysomelidae) in stored cowpea (Vigna unguiculata). International Journal of Tropical Insect Science, 35(4), 172–184. https://doi.org/10.1017/S174275841500017X
Moriarty, F. (1972 November 1). The effects of pesticides on wildlife: Exposure and residues. Science of the Total Environment, 1(3), 267–288. https://doi.org/10.1016/0048-9697(72)90023-x
Moser, V. C. (2014). Fenthion. In P. Wexler (Ed.), Encyclopedia of toxicology (3rd ed., pp. 583–585). Academic Press.
Mougou, I., & Boughalleb-M’hamdi, N. (2018). Biocontrol of Pseudomonas syringae pv. Syringae affecting citrus orchards in Tunisia by using indigenous Bacillus spp. and garlic extract. Egyptian Journal of Biological Pest Control, 28(1), 60. https://doi.org/10.1186/s41938-018-0061-0
Mpumi, N., Mtei, K., Machunda, R., & Ndakidemi, P. A. (2016). The toxicity, persistence and mode of actions of selected botanical pesticides in Africa against insect pests in common beans, P. vulgaris: A review. American Journal of Plant Sciences, 7, 138–151.
Multigner, L., Kadhel, P., Rouget, F., Blanchet, P., & Cordier, S. (2016). Chlordecone exposure and adverse effects in French West Indies populations. Environmental Science and Pollution Research International, 23(1), 3–8. https://doi.org/10.1007/s11356-015-4621-5
Muthomi, J., Fulano, A. M., Wagacha, J. M., & Mwang’ombe, A. W. (2017). Management of snap bean insect pests and diseases by use of antagonistic fungi and plant extracts. Sustainable Agriculture Research, 6(3), 52. https://doi.org/10.5539/sar.v6n3p52
Naqvi, S. M., & Hasan, M. A. (1992). Acetylhomocysteine thiolactone protection against phosphamidon-induced alteration of regional superoxide dismutase activity in the central nervous system and its correlation with altered lipid peroxidation. Indian Journal of Experimental Biology, 30(9), 850–852.
Nawaz, M., Juma, M., & Hongxia, H. (2016). Current status and advancement of biopesticides: Microbial and botanical pesticides. Journal of Entomology and Zoology Studies, 2, 241–246.
Nawaz, M., Mabubu, J. I., & Hua, H. (2016). Current status and advancement of biopesticides: Microbial and botanical pesticides. Journal of Entomology and Zoology Studies, 4(2), 241–246.
Nearing, M. A., Xie, Y., Liu, B., & Ye, Y. (2017). Natural and anthropogenic rates of soil erosion. International Soil and Water Conservation Research, 5(2), 77–84. https://doi.org/10.1016/j.iswcr.2017.04.001
Neeraj, G. S., Kumar, A., Ram, S., & Kumar, V. (2017). Evaluation of nematicidal activity of ethanolic extracts of medicinal plants to meloidogyne incognita (kofoid and white) Chitwood under lab conditions. Indian Journal of Pure & Applied Biosciences, 1, 827–831.
Nefzi, A., Abdallah, B. A. R., Jabnoun-Khiareddine, H., Saidiana-Medimagh, H. R., & Danmi-Remadi. (2016). Antifungal activity of aqueous and organic extracts from Withania somnifera L. against Fusarium oxysporum f. sp. radicis-lycopersici. Journal of Microbial and Biochemical Technology, 3, 144–150.
Ekeh, F. N., Odo, G. E., Nzei, J. I., Ohanu, C. M., Ugwu, F., Ngwu, G., & Reginald, N. (2018). Effects of aqueous and oil leaf extracts of Pterocarpus santalinoides on the maize weevil, Sitophilus zeamais, pest of stored maize grains. African Journal of Agricultural Research, 13(13), 617–626. https://doi.org/10.5897/AJAR2018.13014
Ntalli, N., Bratidou Parlapani, A., Tzani, K., Samara, M., Boutsis, G., Dimou, M., … Monokrousos, N. (2020 February). Thymus citriodorus (Schreb) botanical products as ecofriendly nematicides with bio-fertilizing properties. Plants, 9(2), 202. https://doi.org/10.3390/plants9020202
Ogundele, R. A., Oyedele, D. J., & Adekunle, O. K. (2016). Management of Meloidogyne incognita and other phytonematodes infecting Amaranthus cruentus and Telfairia occidentalis with African marigold (Tagetes erecta) and Siam weed (Chromolaena odorata). Australasian Plant Pathology, 45(5), 537–545. https://doi.org/10.1007/s13313-016-0438-z
Okunlola, A. I., & Akinrinnola, O. (2014). Effectiveness of botanical formulations in vegetable production and bio-diversity preservation in Ondo state, Nigeria. Journal of Horticulture and Forestry, 1, 6–13.
O’Neil, M. J., Smith, A., Heckelman, P. E., & Budavari, S. (2001). The merck index-An encyclopedia of chemicals, drugs, and BioLogicals, 767 p. 4342. Whitehouse Station, NJ: Merck & Co., Inc.
Ortiz-Hernández, M. L., Sánchez-Salinas, E., Dantán-González, E., & Castrejón-Godínez, M. (2013). Pesticide biodegradation: Mechanisms, genetics and strategies to enhance the process. Biodegrad. Life Sciences, 251–287.
Peshin, R. et al. (2009). Integrated pest management: A global overview of history, programs and adoption. Integrated pest management: Innovation-development process (1st ed) (pp. 1–49). Dordrecht: Springer.
Peterson, R. K. D., Higley, L. G., & Pedigo, L. P. (2018). Whatever happened to IPM? American Entomologist, 64(3), 146–150. https://doi.org/10.1093/ae/tmy049
Pohanish, R. P.. D. (2015) R. P. Pohanish (Ed.). Sittig’s handbook of pesticides and agricultural chemicals (2nd ed) (pp. 196–133). William Andrew Publishing.
Porto, A. L. M., Melgar, G. Z., Kasemodel, M. C., & Nitschke, M. (2011). Biodegradation of pesticides. In M. Stoytcheva (Ed.), Pesticides in the Modern World–Pesti- cides Use and Management, 1, Tech (pp. 407–438).
Ranga Rao, G. V., Rupela, O. P., Rao, V. R., & Reddy, Y. V. (2007). Role of biopesticides in crop protection: Present status and future prospects. Indian Journal of Plant Protection, 35(1), 1–9.
Rattner, B. A. (2009). History of wildlife toxicology. Ecotoxicology, 18(7), 773–783. https://doi.org/10.1007/s10646-009-0354-x
Reed, N. R., & Koshlukova, S. (2014a). Chlorfenvinphos. In P. Wexler (Ed.), Encyclopedia of toxicology (3rd ed., pp. 851–854). Academic Press.
Reed, N. R., & Koshlukova, S. (2014b). Heptachlor. In P. Wexler (Ed.), Encyclopedia of toxicology (3rd ed., pp. 840–844). Academic Press.
Riyaz, M., Aamir Iqbal, W. A., Sivasankaran, K., & Ignacimuthu, S. (2020). Impact on farmers’ health due to the pesticide exposure in the agrarian zones of Kashmir valley: A review. Acta Scientific Agriculture, 4(2), 01–07. https://doi.org/10.31080/ASAG.2020.04.impact-on-farmers-health-due-to-the-pesticide-exposure-in-the-agrarian-zones-of-kashmir-valley-a-review.
Riyaz, M., Mathew, P., Paulraj, G., & Ignacimuthu, S. (2018). Entomophily of apple ecosystem in Kashmir valley, India: A review. International Journal of Scientific Research in Biological Sciences (IJSRBS), 5(5), 46–154.
Roberts, D. P., & Mattoo, A. K. (2018). Sustainable agriculture—Enhancing environmental benefits, food nutritional quality and building crop resilience to abiotic and biotic stresses. Agriculture, 8(1), 8. https://doi.org/10.3390/agriculture8010008
Rodgers, K. E., Leung, N., Imamura, T., & Devens, B. H. (1986). Rapid in vitro screening assay for immunotoxic effects of organophosphorus and carbamate insecticides on the generation of cytotoxic T-lymphocyte responses. Pesticide Biochemistry and Physiology, 26(3), 292–301.
Roy, S., Handique, G., Muraleedharan, N., Dashora, K., Roy, S. M., Mukhopadhyay, A., & Babu, A. (2016). Use of plant extracts for tea pest management in India. Applied Microbiology and Biotechnology, 100(11), 4831–4844. https://doi.org/10.1007/s00253-016-7522-8
Saladin, G., & Clément, C. (2005). Physiological side effects of pesticides on non-target plants. Agriculture and Soil Pollution: New Research, 53–86.
Sales, M. D. C., Costa, H. B., Patrícia, M. B. F., Jose, A. V., & Debora, D. M. (2016). Antifungal activity of plant extracts with potential to control plant pathogens in pineapple. Asian Pacific Journal of Tropical Biomedicine, 1, 26–31.
Salhi, N., Mohammed Saghir, S. A., Terzi, V., Brahmi, I., Ghedairi, N., & Bissati, S. (2017). Antifungal activity of aqueous extracts of some dominant Algerian medicinal plants. BioMed Research International, 2017, 7526291. https://doi.org/10.1155/2017/7526291
Sánchez-Bayo, F., & Wyckhuys, K. A. G. (2019). Worldwide decline of the entomofauna: A review of its drivers. Biological Conservation, 232, 8–27. https://doi.org/10.1016/j.biocon.2019.01.020
Saquib, Q., Faisal, M., Ansari, S. M., & Wahab, R. (2019). Phorate triggers oxidative stress and mitochondrial dysfunction to enhance micronuclei generation and DNA damage in human lymphocytes. Saudi Journal of Biological Sciences, 26(7), 1411–1417. https://doi.org/10.1016/j.sjbs.2019.04.008
Sarkar, M., & Kshirsagar, R. (2014). Botanical pesticides: Current challenges and reverse pharmacological approach for future discoveries. Journal of Biofertilizers & Biopesticides, 5(e), 125.
Saunders, M. E. (2018). Insect pollinators collect pollen from wind-pollinated plants: Implications for pollination ecology and sustainable agriculture. Insect Conservation and Diversity, 11(1), 13–31. https://doi.org/10.1111/icad.12243
Sebastian, R., & Raghavan, S. C. (2016). Induction of DNA damage and erroneous repair can explain genomic instability caused by endosulfan. Carcinogenesis, 37(10), 929–940. https://doi.org/10.1093/carcin/bgw081
Shabana, Y. M., Abdalla, M. E., Shahin, A. A., El-Sawy, M. M., Draz, I. S., & Youssif, A. W. (2017). Efficacy of plant extracts in controlling wheat leaf rust disease caused by Puccinia triticina. Egyptian Journal of Basic and Applied Sciences, 4(1), 67–73. https://doi.org/10.1016/j.ejbas.2016.09.002
Sharma, A., Yadav, B., Rohatgi, S., & Yadav, B. (2018). Cypermethrin toxicity: A review. Journal of Forensic Sciences & Criminal Investigation, 9(4) PubMed: 555767.
Sharma, S., Kooner, R., & Arora, R. (2017). Insect pests and crop losses. Inbreeding Insect Resistant Crops for Sustainable Agriculture, 45–66.
Sharoba, A. M., El Mansy, H. A., El Tanahy, H. H., El Waseif, K. H., & Ibrahim, M. A. (2015). Chemical composition, antioxidant and antimicrobial properties of the essential oils and extracts of some aromatic plants, Middle East. Journal of Applied Sciences, 2, 344–352.
Sherman, D. M. (2007 November 27). Tending animals in the global village: A guide to international veterinary medicine. John Wiley & Sons.
Singh, P., Volger, B., & Gordon, E. (2014). Endosulfan. In P. Wexler (Ed.), Encyclopedia of toxicology (3rd ed., pp. 341–343). Academic Press.
Slätmo, E., Fischer, K., & Röös, E. (2017). The framing of sustainability in sustainability assessment frameworks for agriculture. Sociologia Ruralis, 57(3), 378–395. https://doi.org/10.1111/soru.12156
Socorro, J., Durand, A., Temime-Roussel, B., Gligorovski, S., Wortham, H., & Quivet, E. (2016). The persistence of pesticides in atmospheric particulate phase: An emerging air quality issue. Scientific Reports, 6, 33456. https://doi.org/10.1038/srep33456
Srijita, D. (2015). Biopesticides: An ecofriendly approach for pest control. World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS), 4(6), 250–265.
Stevenson, P. C., & Belmain, S. R. (2017). Tephrosia Vogelii. In A pesticide of the future for African farming (pp. 19–22). Boletín SEEA.
Stevenson, P. C., Isman, M. B., & Belmain, S. R. (2017). Pesticidal plants in Africa: A global vision of new biological control products from local uses. Industrial Crops and Products, 110, 2–9. https://doi.org/10.1016/j.indcrop.2017.08.034
Sumitra, A., Kanojia, A. K., Kumar, A., Mogha, N., & Sahu, V. (2014). Biopesticide formulation to control tomato lepidopteran pest menace. Current Science, 7, 1051–1057.
Tang-Péronard, J. L., Andersen, H. R., Jensen, T. K., & Heitmann, B. L. (2011). Endocrine-disrupting chemicals and obesity development in humans: A review. Obesity Reviews, 12(8), 622–636. https://doi.org/10.1111/j.1467-789X.2011.00871.x
Taylor, D. (2011). The complete contented cat: Your ultimate guide to feline fulfilment. Google.co.uk/books?id=Cc5BM_aPegkC&dq=pest+cat+rats&source=gbs_navlinks_s. Retrieved from https://web.archive.org/web/20150615023812/https://books. David & Charles p. 9.
Tesfahunegny, W. (2016). Impact of pesticides on birds from DDT to current fatality: A literature review. Journal of Zoology Studies, 3(2), 44–55.
Thakur, M., & Pathania, D. (2020 January 1). Environmental fate of organic pollutants and effect on human health. In Inabatement of environmental pollutants (pp. 245–262). Elsevier.
Pflanzenschutz-Nachrichten. (1973). "Ancient and medieval plant pathology". The history of integrated pest management. which cites Orlob, G.B., 26 (pp. 65–294). NY: Cornell University.
Thuy, T. T. (2015). Effects of ddt on environment and human health. Journal of Education and Social Sciences, 2, 108–114.
Timoroğlu, İ., Yüzbaşıoğlu, D., Ünal, F., Yılmaz, S., Aksoy, H., & Çelik, M. (2014). Assessment of the genotoxic effects of organophosphorus insecticides phorate and trichlorfon in human lymphocytes. Environmental Toxicology, 29(5), 577–587. https://doi.org/10.1002/tox.21783
Todorov, D., Shishkova, K., Dragolova, D., Hinkov, A., Kapchina-Toteva, V., & Shishkov, S. (2015). Antiviral activity of medicinal plant Nepeta nuda. Biotechnology and Biotechnological Equipment, 1, 39–43.
US EPA (United States Environmental Protection Agency). (2003). Health effects support document for aldrin/dieldrin. EPA 822-R-03-001, 4304t. Office of Water. Health and Ecological Criteria Division.
Wallace, D. R. (2014). Toxaphene. In P. Wexler (Ed.), Encyclopedia of toxicology (3rd ed., pp. 606–609). Academic Press.
Wanzala, W., Wagacha, J. M., Dossaji, S. F., & Gakuubi, M. M. (2016). Bioactive properties of Tagetes minuta L. (Asteraceae) essential oils: A review.
Wegulo, S. N., Baenziger, P. S., Hernandez Nopsa, J. H., Bockus, W. W., & Hallen-Adams, H. (2015). Management of Fusarium head blight of wheat and barley. Crop Protection, 73, 100–107. https://doi.org/10.1016/j.cropro.2015.02.025
Weißhuhn, P., Reckling, M., Stachow, U., & Wiggering, H. (2017). Supporting agricultural ecosystem services through the integration of perennial polycultures into crop rotations. Sustainability, 9(12), 2267. https://doi.org/10.3390/su9122267
Wimalawansa, S. A., & Wimalawansa, S. J. (2014). Agrochemical-related environmental pollution: Effects on human health. Global Journal of Biology, Agriculture and Health Sciences, 3, 72–83.
Yan, Y., Feng, C. C., & Chang, K. T. T. (2017). Towards enhancing integrated pest management based on volunteered geographic information. ISPRS International Journal of Geo-Information, 6(7), 224. https://doi.org/10.3390/ijgi6070224
Yang, X., Huang, Q., Jiang, T., & Xu, H. (2017). Degradation dynamics of azadirachtin in cabbage and soil. Journal of South China Agricultural University, 38(4), 37–40.
Yasmin, S., & D’Souza, D. (2010). Effects of pesticides on the growth and reproduction of earthworm: A review. Applied and Environmental Soil Science, 2010, 1–9. https://doi.org/10.1155/2010/678360
Yue, Q., Xu, X., Hillier, J., Cheng, K., & Pan, G. (2017). Mitigating greenhouse gas emissions in agriculture: From farm production to food consumption. Journal of Cleaner Production, 149, 1011–1019. https://doi.org/10.1016/j.jclepro.2017.02.172
Zarubova, L., Lenka, K., Pavel, N., Miloslav, Z., Ondrej, D., & Skuhrovec, J. (2014). In Botanical pesticides and Their Human Health Safety on the Example of Citrus sinensis Essential oil and Oulema Melanopus Under Laboratory Conditions, Mendel Net (pp. 330–336).
Zhao, L., Feng, C., Hou, C., Hu, L., Wang, Q., & Wu, Y. (2015). First discovery of acetone extract from cottonseed oil sludge as a novel antiviral agent against plant viruses. PLoS One, 2, 1–13.
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Riyaz, M., Mathew, P., Zuber, S.M., Rather, G.A. (2022). Botanical Pesticides for an Eco-Friendly and Sustainable Agriculture: New Challenges and Prospects. In: Bandh, S.A. (eds) Sustainable Agriculture. Springer, Cham. https://doi.org/10.1007/978-3-030-83066-3_5
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