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Towards NMR Spectroscopy In Vivo: II. Relationship between NMR Parameters and Histology

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NMR in the Life Sciences

Part of the book series: NATO ASI Series ((NSSA,volume 107))

Abstract

The future of NMR as an in vivo diagnostic tool, both for imaging techniques and for spectroscopic determinations, requires as a preliminary step a precise tissue characterization. In practice, sound relationships should be established between the histology of a tissue and the relevant NMR parameters.

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References

  1. D. G. Gadian, “Nuclear magnetic resonance and its applications to living systems,” Clarendon Press, Oxford (1982), Chapter 6.

    Google Scholar 

  2. P. A. Bottomley, T. H. Foster, R. E. Argensinger, and L. M. Pfeifer, A review of normal tissue hydrogen relaxation times and relaxation mechanisms from 1–100 MHz: dependence on tissue type, NMR frequency, temperature, excision and age. Med. Phys. 11:425 (1984).

    Article  PubMed  CAS  Google Scholar 

  3. P. A. Bottomley, C. J. Hardy, R. E. Argensinger, and G. R. Allen, Relaxation in pathology: are T1’s and T2’s diagnostic? IV Annual Meeting of the Society of Magnetic Resonance in Medicine, Vol. 1, (1985) P. 28.

    Google Scholar 

  4. K. Gersonde, L. Felsberg, T. Tolxdorff, D. Ratzel, and B. Strobel, Analysis of multiple T2 proton relaxation processes in human head and imaging on the basis of selective and assigned T2 values. Magn. Res. Med. 1:463 (1984).

    Article  CAS  Google Scholar 

  5. K. Gersonde, M. Staemmler, L. Felsberg, and T. Tolxdorff, Tissue characterization by parameter selective whole-body proton imaging, IV Annual Meeting of the Society of Magnetic Resonance in Medicine, Vol. 1 (1985) P. 50.

    Google Scholar 

  6. C. A. Boicelli and A. M. Baldassarri, Practical aspects of in vitro and in vivo T1 and T2 measurements, in “NMR in living systems,” T. Axenrod, Ed., Reidei Publ. Corp., in press.

    Google Scholar 

  7. P. T. Beali and C. F. Hazelwood, Distinction of normal, preneoplastic and neoplastic states by water proton NMR relaxation times, in “NMR imaging,” C. L. Partain, A. E. James Jr., R. D. Rollo, and R. R. Price, Eds., W. B. Saunders Co., Philadelphia (1983), PP. 312–338.

    Google Scholar 

  8. S. S. Ranade, S. Shah, G. V. Talwalker, and S. R. Kasturi, Significance of histopathology in pulsed NMR studies on cancer, in “NMR imaging,” C. L. Partain, A. E. James Jr., F. D. Rollo, and R. R. Price, Eds., W. B. Saunders Co., Philadelphia (1983) PP. 446–452.

    Google Scholar 

  9. S. S. Ranade, S. H. Bharade, G. V. Talwalker, G. K. Sujata, V. T. Shrinivasan, and B. B. Singh, Significance of histopathology in pulsed NMR studies on cancer, Magn. Res. Med. 2:128 (1985).

    Article  CAS  Google Scholar 

  10. P. T. Bealle, Practical methods for biological NMR sample handling, Magn. Res. Imaging 1:165 (1982).

    Article  Google Scholar 

  11. C. I. Chopper, G. Rona, T. Balazs, and R. Gaudry, Comparison of cardiotoxic actions of certain sympathomimetic amines, Can. J. Biochem. 37:35 (1959).

    Google Scholar 

  12. R. Toni, C. A. Boicelli, and A. Bondi. Characterization of human pathological papillary muscles by 1H-NMR spectroscopic and histologic analysis, Int. J. Cardiol., in press.

    Google Scholar 

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© 1986 Plenum Press, New York

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Boicelli, C.A., Baldassarri, A.M., Bondi, A., Giuliani, A.M., Toni, R. (1986). Towards NMR Spectroscopy In Vivo: II. Relationship between NMR Parameters and Histology. In: Bradbury, E.M., Nicolini, C. (eds) NMR in the Life Sciences. NATO ASI Series, vol 107. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-8178-5_13

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  • DOI: https://doi.org/10.1007/978-1-4684-8178-5_13

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-8180-8

  • Online ISBN: 978-1-4684-8178-5

  • eBook Packages: Springer Book Archive

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