Abstract
Coronary angiography remains the standard modality for determining the presence or absence of significant coronary artery disease in 1996. However, in the preceding chapters, angiography has been shown to be limited in predicting the functional significance of a stenosis on coronary blood flow.(1,2) Additionally, visual estimates of percent diameter stenosis are plagued with significant interobserver and intraobserver variability. (3,4) This variability has improved with the development of computer-based quantitative and digital techniques; (5,6) yet, QCA and the physiologic assessment of stenosis severity are weakly correlated, particularly in patients with multivessel disease (7) and intermediate lesions.(8,9) The clinical correlation between functional significance and the best quantitative angiographic techniques in “borderline” coronary artery lesions is poor, secondary to wide 95% confidence intervals.(10)
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Bowers, T.R., Kaplan, B.M., O’Neill, W.W. (1997). Pitfalls and Practical Approach to the Use of Imaging Techniques in Developing Clinical Strategies. In: Klein, L.W. (eds) Coronary Stenosis Morphology: Analysis and Implication. Developments in Cardiovascular Medicine, vol 190. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-6287-0_14
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