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Physical factors such as temperature, pressure, altitude, and humidity affect gases in particular and, thus, should be well understood by the critical care practitioner. A number of useful tables, formulas, and figures follow. Thermal injuries are commonly considered environmental events, and, thus, these formulas and figures are included in this chapter as well.

1 Temperature

Temperature conversion calculations are often done in the management of critically ill patients. Degrees Celsius (°C) and Fahrenheit (°F) are most commonly utilized:

°C to °F

$$ ^\circ {\bf F}=(^\circ{\rm C}\times 9/5)+32$$

°F to °C

$$ ^\circ {\bf C}=(^\circ{\rm F}-32)\times 5/9$$

Occasionally, the Kelvin (K) temperature scale is used, primarily in gas law calculations:

K to °C

$$ {\bf K}=^\circ{\rm C}+273$$

°C to K

$$ ^\circ {\bf C}={\rm K}-273$$

2 Humidity

Relative Humidity

Relative humidity (RH) is usually measured by hygrometers, thus eliminating the need of extracting and measuring the humidity content of the air samples:

$$ \mathbf{RH}=\frac{{\mathrm{Content}\;[\mathrm{mg}/\mathrm{L}\ \mathrm{or}\ \mathrm{mm}\ \mathrm{Hg}]}}{{\mathrm{Capacity}\;[\mathrm{mg}/\mathrm{L}\ \mathrm{or}\ \mathrm{mm}\ \mathrm{Hg}]}}=\% $$

Humidity Deficit

The humidity deficit (HD) represents the maximum humidity capacity at body temperature:

$$ {\bf HD}=\text{Capacity}-\text{content}=\text{mg}/\text{L}$$

where

  • capacity = amount of water the alveolar air can hold at body temperature (also known as absolute humidity)

  • content = humidity content of inspired air (see Table 3.1):

Table 3.1 Humidity capacity of saturated gases from 0 to 43 °C

3 Pressure

Pressure is defined as force per unit area, and there are various ways of measuring this force. One way is that force can be recorded in a form of the height of a column as in the mercury barometer; therefore, it can be recorded in milliliters of mercury (mmHg) pressure or centimeters of water pressure.

To Convert cmH2O to mmHg

$$ {\bf mmHg}={\text{cmH}}_{2}\text{O}\times 0.735$$

To Convert mmHg to cmH2O

$$ {\bf cm{H}_{2}O}=\text{mmHg}\times 1.36$$

Pressure Per Square Inch

A less commonly used conversion in clinical medicine includes converting Psi (pressure per square inch) to mmHg:

$$ {\bf mmHg}=\text{Psi}\times 51.7$$

Pressure-Related Formulas

Other useful pressure-related formulas/facts include:

$$ \mathbf{Total}\;\mathbf{pressure}={P_1} + {P_2} + {P_3}+\cdots\,(\mathrm{Dalton}\hbox{'}\mathrm{s}\ \mathrm{Law}) $$
$$ \begin{array}{ll} {\mathbf{1}\;\mathbf{atmosphere} = 760\ \mathrm{mmHg}} {= 29.921\ \mathrm{in}\ \mathrm{Hg}}{ = 33.93\ \mathrm{ft}\ {{\mathrm{H}}_2}\mathrm{O}} { = 1,034\ \mathrm{cm}\ {{\mathrm{H}}_2}\mathrm{O}} \\ \qquad\qquad\qquad\quad{ = 1,034\ \mathrm{g}/\mathrm{c}{{\mathrm{m}}^2}} { = 14.7\ \mathrm{lb}/\mathrm{in}{.^2}} \end{array} $$

Pressure/Volume Relationships

Useful pressure/volume relationships that can be used in the management of critically ill patients include:

$$ {\bf {Volume_{BTPS}}}={\text{Volume}}_{\text{ATPS}}\times \text{Factor}$$

where

  • VolumeBTPS = gas volume saturated with water at body temperature (37 °C) and ambient pressure [BTPS = barometric temperature pressure saturation]

  • VolumeATPS = gas volume saturated with water at ambient (room) temperature and pressure [ATPS = ambient temperature pressure saturation]

  • Factor represents the factors for converting gas volumes from ATPS to BTPS:

$$ \mathbf{Conversion}\;\mathbf{factor}=\frac{{{P_{\mathrm{B}}}-P{{\mathrm{H}}_2}\mathrm{O}}}{{{P_{\mathrm{B}}}-47}}\times \frac{310 }{{\left( {273+^{\circ}\mathrm{C}} \right)}} $$

See also Table 3.2:

Table 3.2 Factors for converting gas volumes from ATPS to BTPS

4 Altitude

As altitude varies, changes in atmospheric pressure produce alterations in gas density (see Table 3.3):

Table 3.3 Changes in density with altitude assuming a constant temperature

5 Burns

To estimate the extent of burn, the rule of nines for body surface area (BSA) is commonly used:

  • Adults: Arms 9 % each; legs 18 % each; head 9 %; trunk 18 % anterior, 18 % posterior; genitalia 1 %.

  • Children: Arms 9 % each; legs 16 % each; head 13 %; trunk 18 % anterior, 18 % posterior; genitalia 1 %.

  • Infants: Arms 9 % each; legs 14 % each; head 18 %; trunk 18 % anterior, 18 % posterior; genitalia 1 %.

  • In addition, the Lund and Browder chart (Fig. 3.1) can be used (more accurate in children).

    Fig. 3.1
    figure 00031

    Lund and Browder chart for estimation of burn extent