Abstract
Dr. Harter demonstrated for us the structure of visna virus. I would like to elaborate this subject by pointing out the difference in size between the budding virus and the complete virus (Fig. 3A.1). The buds are almost twice the size of the complete virus. Serial sections reveal occasionally a cross-sectional view of the buds, which may falsely appear as detached virus. In reality, however, the majority of particles are not detached and we have hypothesized that the truly detached units have a very short life span and become quickly converted into the complete virus with its dense core. The development of a complete virus involves an intermediate stage during which the dense material appears in a crescent, but is later rearranged in its final form of dense core. Not all of these steps have become apparent and, somewhere in this process, a certain quantity of membrane material disappears.
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© 1977 Springer Science+Business Media New York
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Dubois-Dalcq, M. (1977). Comment/Chapter 3. In: ter Meulen, V., Katz, M. (eds) Slow Virus Infections of the Central Nervous System. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-9883-0_7
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DOI: https://doi.org/10.1007/978-1-4612-9883-0_7
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