Abstract
The past decade has seen rapid advances in the development of techniques for the transplantation of central nervous tissue. Today, good survival of grafted tissue can be achieved, and the establishment of reciprocal connections between the grafted neurons and the host nervous system can be reliably established. This has now been demonstrated in several model systems, including the use of the anterior eye chamber as transplantation site (May 1930, Olson and Seiger 1972, Olson et al. 1979,1980), the development of reciprocal corticotectal and retinotectal connections in grafts to the tectum of the developing brain (Jaeger and Lund 1979, 1980a,b, Lund and Harvey 1981, Lund and Hauschka 1976), the development of reciprocal connections in grafts to the cerebellum (Hallas et al. 1980, Oblinger et al. 1980), and the reestablishment of afferent connections of the denervated hippocampus using grafts, both as a source of replacement neurons (Bjorklund and Stenevi 1977, 1979a, Bjorklund et al. 1976a,b, Kromer et al. 1979) and as tissue bridges (Kromer et al. 1980).
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Dunnett, S.B., Björklund, A., Stenevi, U. (1983). Transplant-Induced Recovery from Brain Lesions: A Review of the Nigrostriatal Model. In: Wallace, R.B., Das, G.D. (eds) Neural Tissue Transplantation Research. Proceedings in Life Sciences. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-5539-0_7
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