Access provided by Autonomous University of Puebla. Download to read the full chapter text
Chapter PDF
Keywords
- Sympathetic Nervous System
- Brown Adipose Tissue
- White Adipose Tissue
- Leukemia Inhibitory Factor
- Sympathetic Neuron
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
References
West JB (1990) Best and Taylor’s physiological basis of medical practice. Williams and Wilkins, Baltimore, MO, 741–753
Afzelius BA (1970) Brown adipose tissue: its gross anatomy, histology, and cytology. In: O Lindberg (ed.): Brown adipose tissue. American Elsevier Publishing Company, New York, 1–31
Crandall DL, Hausman GJ, Kral JG (1997) A review of the microcirculation of adipose tissue: anatomic, metabolic and angiogenic perspectives. Microcirculation 4(2): 211–232
Bamshad M, Aoki VT, Adkison MG, Warren WS, Bartness TJ (1998) Central nervous system origins of the sympathetic nervous system outflow to white adipose tissue. Am J Physiol (Regulatory Integrative Comp Physiol 37) 275(44): R291–R299
Minth CD, Bloom SR, Polak JM, Dixon JE (1984) Cloning, characterization, and DNA sequence of a human cDNA encoding neuropeptide tyrosine. Proc Natl Acad Sci USA 81: 4577–4581
Allen J, Novotny J, Martin J, Heinrich G (1987) Molecular structure of mammalian neuropeptide Y: analysis by molecular cloning and computer-aided comparison with crystal structure of avian homologue. Proc Natl Acad Sci USA 84: 2532–2536
Larhammer D, Ericsson A, Persson H (1987) Structure and expression of the rat neuropeptide Y gene. Proc Natl Acad Sci USA 84: 2068–2072
Lundberg JM, Terenius L, Hokfelt T, Goldstein M (1983) High levels of neuropeptide Y in peripheral noradrenergic neurons in various mammals including man. Neurosci Lett 42: 167–172
DeQuidt ME, Emson PC (1986) Distribution of neuropeptide Y-like immunoreactivity in the rat central nervous system. I. Radioimmunoassay and chromatographic characterization. Neuroscience 18: 527–543
O’Donohue TL, Chronwall BM, Pruss RM, Mezey E, Kiss JZ, Eiden LE, Massari VJ, Tessel RE, Pickel VM, Di Maggio DA et al. (1985) Neuropeptide Y and peptide YY neuronal and endocrine systems. Peptides 6: 755–768
Marek KL, Mains RE (1989) Biosynthesis, development, and regulation of neuropeptide Y in superior cervical ganglion culture. J Neurochem 52(6): 1807–1816
Lee Y (1985) Neuropeptide Y-like immunoreactive structures in the rat stomach with special reference to the noradrenaline neuron system. Gastroenterology 89: 118–126
Hassall CJS, Burnstock G (1987) Immunocytochemical localization of neuropeptide Y and 5-hydroxytryptamine in a subpopulation of amine-handling intracardiac neurons that do not contain dopamine β-hydroxylase in tissue culture. Brain Res 422: 74–82
Hokfelt T (1987) Distribution of neuropeptides with special reference to their coexistence with classical transmitters, in psychopharmacology: the third generation of progress. In: HY Meltzer (ed.): Psychopharmacology: the third generation. Raven Press, New York, 401–416
Franco-Cereceda A, Lundberg JM (1987) Potent effects of neuropeptide Y and calcitonin gene-related peptide on human coronary vascular tone in vitro. Acta Physiol Scand 131: 159–160
Zukowska-Grojec Z, Marks ES, Haass M (1987) Neuropeptide Y is a potent vasoconstrictor and a cardiodepressant in rat. Am J Physiol 253: H1234–H1239
Morris JL (1999) Cotransmission from sympathetic vasoconstrictor neurons to small cutaneous arteries in vivo. Am J Physiol 277(1 Part 2): H58–H64
Smyth L, Bobalova J, Ward SM, Mutafova-Yambolieva VN (2000) Neuropeptide Y is a cotransmitter with norepinephrine in guinea pig inferior mesenteric vein. Peptides 21(6): 835–843
Straub RH, Schaller T, Miller LE, von Horsten S, Jessop DS, Falk W, Scholmerich J (2000) Neuropeptide Y cotransmission with norepinephrine in the sympathetic nerve-macrophage interplay. J Neurochem 75: 2464–2471
Schwartz MW, Woods SC, Porte D, Seeley RJ, Baskin DG (2000) Central nervous system control of food intake. Nature 404: 661–671
Balasubramaniam A (1997) Neuropeptide Y family of hormones: receptor subtypes and antagonists. Peptides 18(3): 445–457
Erickson JC, Hollopeter G, Palmiter RD (1996) Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y. Science 274: 1704–1708
Stephens TW, Basinski M, Bristow PK, Bue-Valleskey JM, Burgett SG, Craft L, Hale J, Hoffmann J, Hsiung HM, Kriauciunas A et al. (1995) The role of neuropeptide Y in the antiobesity action of the obese gene product. Nature 377: 530–532
Blomqvist AG, Herzog H (1997) Y-receptor subtypes — How many more? Trends Neurosci 20: 294–298
Williams G, Cai XJ, Elliott JC, Harrold JA (2004) Anabolic neuropeptides. Physiol Behav 81: 211–222
Hoyle CHV (1999) Neuropeptide families and their receptors: evolutionary perspectives. Brain Res (1999) 848: 1–25
Zukowska-Grojec Z (1998) Neuropeptide Y: an adrenergic cotransmitter, vasoconstrictor, and a nerve-derived vascular growth factor. Adv Pharmacol 42: 125–128
Pedrazzini T, Seydoux J, Kunstner P, Aubert JF, Grouzmann E, Beermann F, Brunner HR (1998) Cardiovascular response, feeding behavior and locomotor activity in mice lacking the NPY Y1 receptor. Nat Med 4(6): 722–726
Naveilhan P, Hassani H, Lucas G, Blakeman KH, Hao JX, Xu XJ, Wiesenfeld-Hallin Z, Thoren P, Ernfors P (2001) Reduced antinociception and plasma extravasation in mice lacking a neuropeptide Y receptor. Nature 409: 513–517
Westfall TC, Mccullough LA, Vickery L, Naes L, Yang CL, Han SP, Egan T, Chen X, Macarthur H (1998) Effects of neuropeptide Y at sympathetic neuroeffector junctions. Adv Pharmacol 42: 106–110
Zukowska-Grojec Z, Karwatowska-Prokopczuk E, Rose W, Rone J, Movafagh S, Ji H, Yeh Y, Chen WT, Kleinman HK, Grouzmann E et al. (1998) Neuropeptide Y: a novel angiogenic factor from the sympathetic nerves and endothelium. Circ Res 83(2): 187–195
Haynes AC, Arch JR, Wilson S, Mcclue S, Buckingham (1998) Characterisation of the neuropeptide Y receptor that mediates feeding in the rat: A role for the Y5 receptor? Regul Pept 75–76: 355–361
Marsh DJ, Hollopeter G, Kafer KE, Palmiter RD (1998) Role of the Y5 neuropeptide Y receptor in feeding and obesity. Nat Med 4(6): 718–721
Mullins DE, Guzzi M, Xia L, Parker EM (2000) Pharmacological characterization of the cloned neuropeptide Y Y6 receptor. Eur J Pharmacol 395: 87–93
Zarjevski N, Cusin I, Vettor R, Rohner-Jeanrenaud F, Jeanrenaud B (1993) Chronic intracerebroventricular neuropeptide-Y administration to normal rats mimics hormonal and metabolic changes of obesity. Endocrinol 133: 1753–1758
Billington CJ, Briggs JE, Grace M, Levine AS (1991) Effects of intracerebroventricular injection of neuropeptide Y on energy metabolism. Am J Physiol 266: R1765–R1770
Allen YS, Adrian TE, Allen JM, Tatemoto K, Crow TJ, Bloom SR, Polak JM (1983) Neuropeptide Y distribution in rat brain. Science 221: 877–879
Broberger C, Johansen J, Johansson C, Schalling M, Hokfelt T (1998) The neuropeptide Y/agouti gene-related protein (AGRP) brain circuitry in normal, anorectic and monosodium glutamate-treated mice. Proc Natl Acad Sci USA 95: 15043–15048
Frankish HM, Dryden S, Hopkins D, Wang Q, Williams G (1995) Neuropeptide Y. The hypothalamus and diabetes: insights into the central control of metabolism. Peptides 16: 757–771
Sahu A, Sninsky CA, Phelps CP, Dube MG, Kalra PS, Kalra SP (1992) Neuropeptide Y release from the paraventricular nucleus increases in association with hyperphagia in streptozotocin-induced diabetic rats. Endocrinology 131: 2979–2985
Dryden S, Wang Q, Frankish HM, Pickavance L, Williams G (1995) Increased neuropeptide Y secretion in the hypothalamic paraventricular nucleus of obese (fa/fa) zucker rats. Brain Res 690: 185–189
Barzilai N, Wang J, Massilon D, Vuguin P, Hawkins M, Rossetti L (1997) Leptin selectively decreases visceral adiposity and enhances insulin action. J Clin Invest 100(12): 3105–3110
Meier U, Gressner AM (2004) Endocrine regulation of energy metabolism: review of pathobiochemical and clinical chemical aspects of leptin, ghrelin, adiponectin, and resistin. Clin Chem 50(9): 1511–1525
Schwartz MW, Baskin DG, Bukoswki TR, Kuijper JL, Foster D, Lasser G, Prunkard DE, Porte D, Woods SC, Seeley RJ et al. (1996) Specificity of leptin action on elevated blood glucose levels and hypothalamic neuropeptide Y gene expression in ob/ob mice. Diabetes 44: 147–151
Batterham RL, Cowley MA, Small CJ, Herzog H, Cohen MA, Dakin CL, Wren AM, Brynes AE, Low MJ, Ghatei MA et al. (2002) Gut hormone PYY(3–36) physiologically inhibits food intake. Nature 418(6898): 650–654
Sainsbury A, Schwarzer C, Couzens M, Herzog H (2002) Y2 receptor deletion attenuates the type 2 diabetic syndrome of ob/ob mice. Diabetes 51(12): 3420–3427
Strack AM, Sawyer WB, Hughes JH, Platt KB, Loewy AD (1989) A general pattern of CNS innervation of the sympathetic outflow demonstrated by transneuronal pseudorabies viral infections. Brain Res 491: 156–162
Turtzo LC, Lane MD (2002) Completing the loop: neuron-adipocyte interactions and the control of energy homeostasis. Horm Metab Res 34: 607–615
Lawrence VJ, Coppack SW (2000) The endocrine function of the fat cell-regulation by the sympathetic nervous system. Horm Metab Res 32: 453–467
Bartness TJ, Bamshad M (1998) Innervation of mammalian white adipose tissue: implications for the regulation of total body fat. Am J Physio (Regulatory Integrative Comp Physiol) 275(44): R1399–R1411
Bowers RR, Festuccia WT, Song CK, Shi H, Migliorini RH, Bartness TJ (2004) Sympathetic innervation of white adipose tissue and its regulation of fat cell number. Am J Physiol Regul Integr Comp Physiol 286(6): R1167–R1175
Trayhurn P, Ashwell M (1987) Control of white and brown adipose tissues by the autonomic nervous system. Proc Nutr Soc 46: 135–142
Järvi R, Helen P, Pelto-Huikko M, Hervonen A (1986) Neuropeptide Y (NPY)-like immunoreactivity in rat sympathetic neurons and small granule-containing cells. Neurosci Lett 67: 223–227
Mains RE, Patterson PH (1973) Primary cultures of dissociated sympathetic neurons: I. establishment of long-term growth in culture and studies of differentiated properties. J Cell Biol 59: 329–345
Freidin M, Dougherty M, Kessler JA (1993) Cell density regulates neuropeptide Y expression in cultured sympathetic neurons. Brain Res 615: 135–140
Allen JM, Martin JB, Heinrich G (1987) Neuropeptide Y gene expression in PC12 cells and its regulation by nerve growth factor: a model for developmental regulation. Mol Brain Res 3: 39–43
Nawa H, Nakanishi S, Patterson P (1991) Recombinant cholinergic differentiation factor (leukemia inhibitory factor) regulates sympathetic neuron phenotype by alterations in the size and amounts of neuropeptide mRNAs. J Neurochem 56: 2147–2150
Zigmond RE, Sun Y (1997) Regulation of neuropeptide expression in sympathetic neurons: paracrine and retrograde influences. Ann NY Acad Sci, 181–197
Turtzo LC, Marx R, Lane MD (2001) Cross-talk between sympathetic neurons and adipocytes in coculture. Proc Natl Acad Sci USA 98: 12385–12390
Schwartz MW, Sipols AJ, Marks JL, Sanacora G, White JD, Scheurink A, Kahn SE, Baskin DG, Woods SC, Figlewicz DP et al. (1992) Inhibition of hypothalamic neuropeptide Y gene expression by insulin. Endocrinology 130(6): 3608–3616
Beck B (2001) KO’s and organisation of peptidergic feeding behavior mechanisms. Neurosci Biobehav Rev 25: 143–158
Mercer JG, Speakman JR (2001) Hypothalamic neuropeptide mechanisms for regulating energy balance: from rodent models to human obesity. Neurosci Biobehav Rev 25: 101–116
Bray GA (2000) Reciprocal relation of food intake and sympathetic activity: experimental observations and clinical implications. Int J Obes Relat Metab Disord 24(Suppl 2): S8–17
Martinez JA, Aguado M, Fruhbeck G (2000) Interactions between leptin and NPY affecting lipid mobilization in adipose tissue. J Physiol Biochem 56(1): 1–8
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2006 Birkhäuser Verlag/Switzerland
About this chapter
Cite this chapter
Turtzo, L.C., Lane, M.D. (2006). NPY and neuron-adipocyte interactions in the regulation of metabolism. In: Zukowska, Z., Feuerstein, G.Z. (eds) NPY Family of Peptides in Neurobiology, Cardiovascular and Metabolic Disorders: from Genes to Therapeutics. Experientia Supplementum, vol 95. Birkhäuser Basel. https://doi.org/10.1007/3-7643-7417-9_10
Download citation
DOI: https://doi.org/10.1007/3-7643-7417-9_10
Publisher Name: Birkhäuser Basel
Print ISBN: 978-3-7643-7155-5
Online ISBN: 978-3-7643-7417-4
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)