Abstract
Effects of pathophysiological conditions and pharmacological intervention on transmural propagation are computed for the virtual ventricular wall. ST depression during sub-endocardial ischaemia and unidirectional functional block in the vulnerable window during Class III drug action are explained by changes induced in the transmural dispersion of action potential duration.
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Aslanidi, O.V., Lambert, J.L., Srinivasan, N.T., Holden, A.V. (2005). Virtual Ventricular Wall: Effects of Pathophysiology and Pharmacology on Transmural Propagation. In: Frangi, A.F., Radeva, P.I., Santos, A., Hernandez, M. (eds) Functional Imaging and Modeling of the Heart. FIMH 2005. Lecture Notes in Computer Science, vol 3504. Springer, Berlin, Heidelberg. https://doi.org/10.1007/11494621_17
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DOI: https://doi.org/10.1007/11494621_17
Publisher Name: Springer, Berlin, Heidelberg
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