Overview
- Provides an up-to-date overview of yeast cell surface engineering
- Explains the basic principles and practical strategies
- Discusses the latest medical and industrial applications
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About this book
This book provides a detailed and up-to-date overview of all aspects of yeast cell surface engineering, including fundamental principles, practical strategies for the construction of engineered yeasts, as well as medical and industrial applications. The technique makes it possible to add eukaryotic modifications to the surface-displayed proteins/peptides, which is of significant value in basic and applied research. Generally referred to as an arming (molecular display) technology, it allows yeast to be used as a whole-cell biocatalyst for a range of purposes, including bio-energy production, pollutant removal, recovery of rare metal ions, and preparation of functional cells, all of which are comprehensively covered in the book. Among the medical applications discussed are in vitro antibody preparation and the production of oral vaccines. In addition, it presents the latest advances in protein engineering and high-throughput screening for directed evolution of enzymes. The book enables graduate students and researchers to gain a deeper, comprehensive understanding of the technology, and offers further inspiration for researchers and industrial experts in this rapidly evolving field.
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Keywords
- Molecular display
- Arming technology
- Combinatorial engineering
- Surface displayed protein
- Protein
- Peptide
- Eukaryotic secretory pathways
- Whole-cell biocatalyst
- Biofuel production
- Pollutant removal
- Bioremediation
- Antibody
- Vaccine
- Cell factory
- Resource recovery
- Aquatic purification
- Enzyme evolution
- antibodies
Table of contents (13 chapters)
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Front Matter
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Part I
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Front Matter
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Part II
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Front Matter
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Part IV
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Front Matter
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Editors and Affiliations
About the editor
Prof. Mitsuyoshi Ueda
Laboratory of Biomacromolecular Chemistry, Division of Applied Life Sciences, Department of Applied Biochemistry, Graduate School of Agriculture, Kyoto University, Japan
Bibliographic Information
Book Title: Yeast Cell Surface Engineering
Book Subtitle: Biological Mechanisms and Practical Applications
Editors: Mitsuyoshi Ueda
DOI: https://doi.org/10.1007/978-981-13-5868-5
Publisher: Springer Singapore
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Nature Singapore Pte Ltd. 2019
Hardcover ISBN: 978-981-13-5867-8Published: 09 May 2019
eBook ISBN: 978-981-13-5868-5Published: 23 April 2019
Edition Number: 1
Number of Pages: VIII, 185
Number of Illustrations: 35 b/w illustrations, 41 illustrations in colour
Topics: Biomedical Engineering/Biotechnology, Eukaryotic Microbiology, Antibodies, Medical Microbiology, Environmental Engineering/Biotechnology, Cell Biology