Overview
- Introduces new therapies available for treating chronic hepatitis C
- Describes Direct Acting Antiviral Agents (DAA), which have an excellent anti-viral effect on virus replication
- Provides cutting-edge information not only for hepatologists, but also for researchers, clinical residents, and medical students
Buy print copy
About this book
This book introduces readers to Direct Acting Antiviral (DAAs) agents, newly developed drugs to treat chronic hepatitis C virus infection, which have an excellent anti-viral effect on virus replication. These drugs have been developed to enhance the effect of interferon and ribavirin, as the resistant strains against each drug have been described both in vitro and in vivo and the existences of naturally occurring variants have been reported. However, since the combination of different classes of DAAs is sufficient to completely eradicate the virus without the need for interferon or ribavirin, the current treatment regimen does not include interferon. Ribavirin is used in combination with sofosbuvir, a potent polymerase inhibitor, to enhance its antiviral effects.
Hepatitis C Virus Treatment offers readers a comprehensive guide to hepatitis C; describing the resistance profiles against these drugs and shedding light on the difficulties involved in DAA therapy and the direction of future treatments, it will equip doctors to understand the essentials of treating the disease. It also describes in detail new and innovative DAA treatments, the effects of the agents, and the characteristics of resistance, providing cutting-edge information not only for hepatologists, but also for researchers, clinical residents, and medical students.Similar content being viewed by others
Keywords
Table of contents (8 chapters)
-
Front Matter
Editors and Affiliations
About the editor
Prof. Kazuaki ChayamaDepartment of Gastroenterology and Metabolism, Applied Life Sciences, Graduate School of Biomedical and Health Sciences, Hiroshima University
Bibliographic Information
Book Title: Hepatitis C Virus Treatment
Book Subtitle: Highly Effective Therapy with Direct Acting Antivirals and Associated Viral Resistance
Editors: Kazuaki Chayama
DOI: https://doi.org/10.1007/978-981-10-2416-0
Publisher: Springer Singapore
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer Science+Business Media Singapore 2017
Hardcover ISBN: 978-981-10-2415-3Published: 14 November 2016
Softcover ISBN: 978-981-10-9610-5Published: 05 July 2018
eBook ISBN: 978-981-10-2416-0Published: 01 November 2016
Edition Number: 1
Number of Pages: VII, 75
Number of Illustrations: 9 b/w illustrations, 14 illustrations in colour
Topics: Hepatology, Virology, Drug Resistance