Overview
- A comprehensive review
- Written by leading experts
- Richly illustrated
- Includes supplementary material: sn.pub/extras
Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 369)
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About this book
Hepatitis C virus (HCV), a major causative agent of chronic liver disease, is spread throughout the world and around 170 million people are persistently infected. In this volume, world-leading experts in the field of HCV research have compiled the most recent scientific advances to provide a comprehensive and very timely overview of the various facets of HCV. The book starts with a discussion of the possible origin of HCV and its spread among the human population. The focus of the subsequent chapters is on available cell culture and in vivo models before shifting to the molecular and cellular principles underlying the viral replication cycle. These chapters are complemented by insightful descriptions of the innate and adaptive immune responses to HCV as well as the virus-associated pathogenesis. Finally, the development of antiviral therapies, which is closely linked with progress in basic research, and the implementation of those therapies into present and future daily clinical practice are highlighted.
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Table of contents (13 chapters)
Editors and Affiliations
Bibliographic Information
Book Title: Hepatitis C Virus: From Molecular Virology to Antiviral Therapy
Editors: Ralf Bartenschlager
Series Title: Current Topics in Microbiology and Immunology
DOI: https://doi.org/10.1007/978-3-642-27340-7
Publisher: Springer Berlin, Heidelberg
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 2013
Hardcover ISBN: 978-3-642-27339-1Published: 15 March 2013
Softcover ISBN: 978-3-642-42936-1Published: 09 April 2015
eBook ISBN: 978-3-642-27340-7Published: 12 March 2013
Series ISSN: 0070-217X
Series E-ISSN: 2196-9965
Edition Number: 1
Number of Pages: VIII, 346
Number of Illustrations: 14 b/w illustrations, 20 illustrations in colour
Topics: Virology, Immunology, Drug Resistance, Hepatology