Overview
- Presents a comprehensive overview of the actin modifying actions of bacterial toxins
- Bridges the gap between common knowledge, new findings and new concepts for therapeutic approaches
- A valuable resource for microbiologists, cell biologists, and clinicians whose work involves infectious diseases
- Includes supplementary material: sn.pub/extras
Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 399)
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About this book
This volume describes the mechanisms which bacteria have created to secure their survival, proliferation and dissemination by subverting the actin cytoskeleton of host cells. Bacteria have developed a veritable arsenal of toxins, effector proteins and virulence factors that allow them to modify the properties of the intracellular actin cytoskeleton for their own purposes. Bacterial factors either modify actin directly as the main component of this part of the cytoskeleton or functionally subvert regulatory or signalling proteins terminating at the actin cytoskeleton.
In short, this volume provides an overview of the various tricks bacteria have evolved to “act on actin” in order to hijack this essential host cell component for their own needs. As such, it will be of interest to scientists from many fields, as well as clinicians whose work involves infectious diseases.
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Keywords
Table of contents (11 chapters)
Editors and Affiliations
About the editor
Institut für Anatomie
Abteilung für Anatomie und molekulare Embryologie
e-mail: Hans.Mannherz@ruhr-uni-bochum.de
Bibliographic Information
Book Title: The Actin Cytoskeleton and Bacterial Infection
Editors: Hans Georg Mannherz
Series Title: Current Topics in Microbiology and Immunology
DOI: https://doi.org/10.1007/978-3-319-50047-8
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2017
Hardcover ISBN: 978-3-319-50046-1Published: 13 February 2017
Softcover ISBN: 978-3-319-84305-6Published: 13 July 2018
eBook ISBN: 978-3-319-50047-8Published: 07 February 2017
Series ISSN: 0070-217X
Series E-ISSN: 2196-9965
Edition Number: 1
Number of Pages: X, 242