Overview
- Presents a state-of-the-art overview of biomechanical and mechanobiological modeling and simulation of soft biological tissues
- Particular attention is focused on microstructural and multi-scale modeling, finite element implementation and simulation of cells and tissues
- The essential ingredients of continuum mechanics are provided
- Includes supplementary material: sn.pub/extras
Part of the book series: Studies in Mechanobiology, Tissue Engineering and Biomaterials (SMTEB, volume 20)
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About this book
The mechanics of the whole cell and sub-cellular components as well as the extracellular matrix structure and mechanotransduction are described. In particular, the formation and remodeling of stress fibers, cytoskeletal contractility, cell adhesion and the mechanical regulation of fibroblast migration in healing myocardial infarcts are discussed. The essential ingredients of continuum mechanics are provided. Constitutive models of fiber-reinforced materials with anemphasis on arterial walls and the myocardium are discussed and the important influence of residual stresses on material response emphasized. The mechanics and function of the heart, the brain and adipose tissues are discussed as well. Particular attention is focused on microstructural and multi-scale modeling, finite element implementation and simulation of cells and tissues.
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Table of contents (7 chapters)
Editors and Affiliations
Bibliographic Information
Book Title: Biomechanics: Trends in Modeling and Simulation
Editors: Gerhard A. Holzapfel, Ray W. Ogden
Series Title: Studies in Mechanobiology, Tissue Engineering and Biomaterials
DOI: https://doi.org/10.1007/978-3-319-41475-1
Publisher: Springer Cham
eBook Packages: Engineering, Engineering (R0)
Copyright Information: Springer International Publishing Switzerland 2017
Hardcover ISBN: 978-3-319-41473-7Published: 23 September 2016
Softcover ISBN: 978-3-319-82364-5Published: 15 June 2018
eBook ISBN: 978-3-319-41475-1Published: 14 September 2016
Series ISSN: 1868-2006
Series E-ISSN: 1868-2014
Edition Number: 1
Number of Pages: IX, 316
Number of Illustrations: 66 b/w illustrations, 63 illustrations in colour
Topics: Biomedical Engineering and Bioengineering, Mathematical Modeling and Industrial Mathematics, Theoretical and Applied Mechanics, Biomaterials, Biological and Medical Physics, Biophysics